Patient Preferences of a Resect and Discard Paradigm
研究概览
详细说明
The American Society of Gastrointestinal Endoscopy (ASGE) published a review article on a new paradigm in colorectal cancer screening termed "resect and discard". This new paradigm challenges the current practice of sending all colorectal polyps, regardless of appearance or size, to pathology for analysis. "Resect and Discard" describes a new approach in which small polyps could be removed, but be discarded instead of sent for pathology analysis. This is based on data showing that gastroenterologists can predict the pathology of small colorectal polyps with 80-90% accuracy, and that discarding small polyps would not alter surveillance recommendations.
Neither the ASGE document nor published research, however, assessed patient attitudes toward this approach. This study surveyed patients prior to first time screening colonoscopy, in order to determine their preferences about the resect and discard approach; specifically would patients be willing to pay for pathology analysis of small colorectal polyps with their own money, and what factors influence their decision. We also inquired about factors that would influence their decision to pay/not pay pathology costs themselves.
研究类型
注册 (实际的)
联系人和位置
学习地点
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Missouri
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Saint Louis、Missouri、美国、63110
- Washington University in St. Louis
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
取样方法
研究人群
描述
Inclusion Criteria:
• Indication for colonoscopy is screening or routine polyp surveillance
Exclusion Criteria:
- Indication for colonoscopy other than screening or surveillance
- Colon cancer identified at time of colonoscopy
- Known polyposis syndrome, or polyposis identified at colonoscopy
学习计划
研究是如何设计的?
设计细节
研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
---|---|---|
Number of participants willing to pay out of pocket for pathology costs when a diminutive polyp is found.
大体时间:June, 2012 to March, 2014: up to 2 years
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This outcome is measured in percentage.
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June, 2012 to March, 2014: up to 2 years
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
---|---|---|
The factors that influence patients' decisions to pay or not pay for pathology costs with their own money.
大体时间:June, 2012 to March, 2014: up to 2 years
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These factors were measured using univariate analysis with generation of odds ratios and 95% confidence intervals.
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June, 2012 to March, 2014: up to 2 years
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合作者和调查者
调查人员
- 首席研究员:Dayna S Early, MD、Washington University School of Medicine
出版物和有用的链接
一般刊物
- Rex DK. Narrow-band imaging without optical magnification for histologic analysis of colorectal polyps. Gastroenterology. 2009 Apr;136(4):1174-81. doi: 10.1053/j.gastro.2008.12.009. Epub 2008 Dec 10.
- Hassan C, Pickhardt PJ, Rex DK. A resect and discard strategy would improve cost-effectiveness of colorectal cancer screening. Clin Gastroenterol Hepatol. 2010 Oct;8(10):865-9, 869.e1-3. doi: 10.1016/j.cgh.2010.05.018. Epub 2010 Jun 1.
- Vu HT, Sayuk GS, Gupta N, Hollander T, Kim A, Early DS. Patient preferences of a resect and discard paradigm. Gastrointest Endosc. 2015 Aug;82(2):381-384.e1. doi: 10.1016/j.gie.2015.01.042. Epub 2015 Apr 22.
研究记录日期
研究主要日期
学习开始
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (估计)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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