Effects of Community-center Based Dietary Intervention on Frailty Prevention and Regression in the Elderly.
Associations Between Various Geriatric Syndromes and Nutrition Status and Dietary Pattern in Elderly
研究概览
研究类型
注册 (实际的)
阶段
- 不适用
联系人和位置
学习地点
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Taipei、台湾、115
- Institute of Biomedical Sciences, Academia Sinica
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参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Aged 65 years or older
- Able to walk independently for 14 meters within 1 minute
- Willing to sign the informed consent
Exclusion Criteria:
- Under dietary control by doctors' instructions
- With mental illness, mental disorders, or unable to communicate
- With severe diseases such as under treatments for cancer
学习计划
研究是如何设计的?
设计细节
- 主要用途:治疗
- 分配:随机化
- 介入模型:并行分配
- 屏蔽:单身的
武器和干预
参与者组/臂 |
干预/治疗 |
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安慰剂比较:Exercise
The control group received weekly one-hour group exercise training for 3 months.
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The group exercise training was held in each community center.
The group exercise training contained aerobic exercise, complex physical fitness exercise, muscle training, and balance and coordination training.
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实验性的:Exercise and nutrition
The intervention group had weekly one-hour group exercise training the same as the control and an additional weekly one-hour group nutrition session for 3 months.
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The group exercise training was held in each community center.
The group exercise training contained aerobic exercise, complex physical fitness exercise, muscle training, and balance and coordination training.
The intervention programs included: (a) training on-site staffs to use motivational interview techniques to communicate, to estimate participant's energy requirements, and to learn how to provide proper amounts of foods to individual elderlies, (b) nutrition grouped activities on ①know my plate, ②wholegrains, ③ drinking teas with dairy, and nuts, ④novel ways to eat fruit and vegetables, ⑤healthy breakfast ideas.
In the first month, participants were intervened with the activities laid out above; in the second month, participants were intervened with qualitative discussion on elders' dietary changes; in the third month, participants were intervened with designed activities that helped break down barriers in order to establish a long-term change in dietary habits.
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研究衡量的是什么?
主要结果指标
结果测量 |
措施说明 |
大体时间 |
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Change from baseline in intake frequency (portion per day) on the six food groups at months 3 and 6.
大体时间:Baseline, Month 3 and Month 6
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The six food groups include:
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Baseline, Month 3 and Month 6
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Change from baseline in the ratios of concentration on urinary nutritional biomarkers at months 3 and 6.
大体时间:Baseline, Month 3 and Month 6
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The concentrations of the following urinary nutritional biomarkers were determined: urinary urea nitrogen (mg/dL), urinary calcium (mg/dl), urinary potassium (mmol/L), urinary magnesium (mg/dL), and urinary creatinine (mg/dL). The urinary urea nitrogen to creatinine ratios, urinary calcium to creatinine ratios, urinary potassium to creatinine ratios, and urinary magnesium to creatinine ratios was estimated at baseline, moths 3 and 6. |
Baseline, Month 3 and Month 6
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Change from baseline in frailty status at months 3 and 6.
大体时间:Baseline, Month 3 and Month 6
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Frailty status was defined using modified Linda Fried criteria with cutoff points from the investigators' previous intervention studies. Five frail phenotypes were assigned: (1) unintentional weight loss, (2) self-reported exhaustion, (3) weak grip strength, (4) slow gait speed, and (5) low level of physical activity. To estimate frailty, participants scored 1 point from each phenotype if any of these were satisfied; a maximum score of five was possible. Participants were classified by their point scores as follows: 'robust' for 0 point; 'pre-frail' for 1 or 2 points; and 'frail' for ≥3. |
Baseline, Month 3 and Month 6
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次要结果测量
结果测量 |
措施说明 |
大体时间 |
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Change from baseline in the score of digit span at months 3 and 6.
大体时间:Baseline, Month 3 and Month 6
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A digit span task is used to measure working memory's number storage capacity.
Subjects are read a sequence of numbers and asked to repeat the same sequence back to the examiner in order (forward span) or in reverse order (backward span).
The score is the length of the longest correctly repeated sequence.
The maximum number of digits in a sequence is 9 and the minimum number of digits in a sequence is 2. The higher scores mean a better outcome.
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Baseline, Month 3 and Month 6
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Change from baseline in the scores on the Geriatric Depression Scale at months 3 and 6.
大体时间:Baseline, Month 3 and Month 6
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The Geriatric Depression Scale (GDS) is a self-report measure of depression in older adults.
Scores of 0-4 are considered normal, depending on age, education, and complaints; 5-8 indicate mild depression; 9-11 indicate moderate depression; and 12-15 indicate severe depression.
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Baseline, Month 3 and Month 6
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合作者和调查者
调查人员
- 首席研究员:Wen-Harn Pan, PhD、Academia Sinica, Taiwan
出版物和有用的链接
一般刊物
- Hsieh TJ, Su SC, Chen CW, Kang YW, Hu MH, Hsu LL, Wu SY, Chen L, Chang HY, Chuang SY, Pan WH, Hsu CC. Individualized home-based exercise and nutrition interventions improve frailty in older adults: a randomized controlled trial. Int J Behav Nutr Phys Act. 2019 Dec 2;16(1):119. doi: 10.1186/s12966-019-0855-9. Erratum In: Int J Behav Nutr Phys Act. 2019 Dec 23;16(1):136.
- Wu SY, Hsu LL, Hsu CC, Hsieh TJ, Su SC, Peng YW, Guo TM, Kang YW, Pan WH. Dietary education with customised dishware and food supplements can reduce frailty and improve mental well-being in elderly people: A single-blind randomized controlled study. Asia Pac J Clin Nutr. 2018;27(5):1018-1030. doi: 10.6133/apjcn.032018.02.
研究记录日期
研究主要日期
学习开始 (实际的)
初级完成 (实际的)
研究完成 (实际的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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Exercise的临床试验
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University of Maryland, BaltimoreNational Institute on Aging (NIA)完全的