Dietary Supplementation and Hydration
This study will examine the effects of protein drinks on markers of hydration in healthy young males and females.
研究概览
研究类型
注册 (估计的)
阶段
- 不适用
联系人和位置
学习地点
-
-
Leicestershire
-
Loughborough、Leicestershire、英国
- Loughborough University
-
-
参与标准
资格标准
适合学习的年龄
接受健康志愿者
有资格学习的性别
描述
Inclusion Criteria:
- Healthy, physically active
Exclusion Criteria:
Are not between the ages of 18-40. If you are not considered at least recreationally physically active (at least meeting the WHO criteria) - Tier 1 or Tier 2 on the Participant Classification Framework (https://pubmed.ncbi.nlm.nih.gov/34965513/).
Have metabolic, inflammatory, vascular, renal disease or any other complication that would contradict the study procedures or risk your health.
Currently taking medication or supplements that may interfere with the study outcomes.
- Do not satisfactorily complete the health history survey
- You have any allergies to the ingredients in the supplements
学习计划
研究是如何设计的？
设计细节
- 主要用途：治疗
- 分配：随机化
- 介入模型：交叉作业
- 屏蔽：三倍
武器和干预
参与者组/臂 |
干预/治疗 |
|---|---|
|
实验性的：Protein
Protein (10 g of protein powder and 500 ml of water) |
10 g of protein powder in 500 ml water 10 g of protein powder, plus sodium chloride (20 mmol/L) in 500 ml of water |
|
实验性的：Protein+
Protein (10 g of protein powder, 500 ml of water, sodium chloride, 20 mmol/L) |
10 g of protein powder in 500 ml water 10 g of protein powder, plus sodium chloride (20 mmol/L) in 500 ml of water |
|
安慰剂比较：Placebo control
Water (500 ml) |
Water (500 ml) |
研究衡量的是什么？
主要结果指标
结果测量 |
大体时间 |
|---|---|
|
Urine output (mass in grams over 180 min collection period)
大体时间：180 minutes
|
180 minutes
|
次要结果测量
结果测量 |
措施说明 |
大体时间 |
|---|---|---|
|
Subjective measures of thirst (Likert scale, 0-10; 0 = low, 10 = high)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Urine specific gravity (AU)
大体时间：Pre - then 60, 120, 180 mins post
|
Pre - then 60, 120, 180 mins post
|
|
|
Blood sodium concentrations (mmol)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Blood chloride concentrations (mmol)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Blood potassium (mmol)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Urine sodium (mmol)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Urine chloride (mmol)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Urine potassium (mmol)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Plasma volume change (% change)
大体时间：Pre - then 60, 180 minutes
|
Pre - then 60, 180 minutes
|
|
|
Plasma albumin concentrations
大体时间：Pre - then 60, 180 minutes
|
ELISA measurement |
Pre - then 60, 180 minutes
|
|
Plasma aldosterone concentrations
大体时间：Pre - then 60, 180 minutes
|
ELISA measurement |
Pre - then 60, 180 minutes
|
|
Subjective measure of hunger (Likert scale, 0-10; 0 = low, 10 = high)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Subjective measure of gastrointestinal stress (Likert scale, 0-10; 0 = low, 10 = high)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Plasma insulin concentrations
大体时间：Pre - then 60, 180 minutes
|
ELISA measurement |
Pre - then 60, 180 minutes
|
|
Subjective measures of hunger (Likert scale, 0-10; 0 = low, 10 = high)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Subjective measures of stomach fullness (Likert scale, 0-10; 0 = low, 10 = high)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Subjective measures of nausea (Likert scale, 0-10; 0 = low, 10 = high)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
|
|
Beverage hydration index (AU)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Calculated as the ratio of cumulative urine mass for water/cumulative urine mass of the test beverages |
Pre - then 30, 60, 120, 180 mins post
|
|
Plasma osmolality (mOsm/L)
大体时间：Pre - 60, 180 mins post
|
Pre - 60, 180 mins post
|
|
|
Blood glucose (mmol/L)
大体时间：Pre - then 30, 60, 120, 180 mins post
|
Pre - then 30, 60, 120, 180 mins post
|
合作者和调查者
研究记录日期
研究主要日期
学习开始 (估计的)
初级完成 (估计的)
研究完成 (估计的)
研究注册日期
首次提交
首先提交符合 QC 标准的
首次发布 (实际的)
研究记录更新
最后更新发布 (实际的)
上次提交的符合 QC 标准的更新
最后验证
更多信息
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