- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00094315
Development of Human Laboratory Study Model of Cocaine Relapse Prevention II - 1
January 10, 2017 updated by: National Institute on Drug Abuse (NIDA)
Cocaine Relapse Prevention II
To study of classical conditioning mechanisms associated with arousal, craving and cocaine use.
Study Overview
Detailed Description
This is a single-site, double-blind, placebo-controlled crossover study of classical conditioning mechanisms associated with arousal, craving and cocaine use.
Study Type
Interventional
Enrollment
16
Phase
- Phase 1
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Texas
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San Antonio, Texas, United States, 78284
- University of Texas Health Science Center
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 55 years (Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Be English-speaking volunteers who are cocaine dependent
- Be non-treatment seeking at the time of the study
- Meet DSM-IV criteria for cocaine dependence
- Have ECG showing normal sinus rhythm, normal conductivity, and non clinically significant arrhythmias
- Females must provide a negative pregnancy test and agree to use birth control
- Have baseline laboratory tests within normal limits
Exclusion Criteria:
- Please contact site for more information
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
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Cocaine assessment
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Stimulated and non-stimulated craving
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Investigators
- Principal Investigator: John Roache, Ph.D., University of Texas
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
September 1, 2004
Study Completion
July 1, 2005
Study Registration Dates
First Submitted
October 15, 2004
First Submitted That Met QC Criteria
October 14, 2004
First Posted (Estimate)
October 15, 2004
Study Record Updates
Last Update Posted (Estimate)
January 11, 2017
Last Update Submitted That Met QC Criteria
January 10, 2017
Last Verified
September 1, 2005
More Information
Terms related to this study
Additional Relevant MeSH Terms
- Mental Disorders
- Chemically-Induced Disorders
- Substance-Related Disorders
- Cocaine-Related Disorders
- Physiological Effects of Drugs
- Neurotransmitter Agents
- Molecular Mechanisms of Pharmacological Action
- Central Nervous System Depressants
- Peripheral Nervous System Agents
- Sensory System Agents
- Anesthetics
- Neurotransmitter Uptake Inhibitors
- Membrane Transport Modulators
- Dopamine Agents
- Anesthetics, Local
- Dopamine Uptake Inhibitors
- Vasoconstrictor Agents
- Cocaine
Other Study ID Numbers
- NIDA-CTO-0014-1
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Cocaine-Related Disorders
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Baylor College of MedicineNational Institute on Drug Abuse (NIDA)CompletedSubstance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine AddictionUnited States
-
Baylor College of MedicineNational Institute on Drug Abuse (NIDA)CompletedSubstance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine AddictionUnited States
-
Baylor College of MedicineNational Institute on Drug Abuse (NIDA)CompletedSubstance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine AddictionUnited States
-
New York State Psychiatric InstituteNational Institute on Drug Abuse (NIDA); Columbia UniversityNot yet recruitingCocaine Use Disorder | Cocaine Dependence | Cocaine Use | Cocaine Use Disorder, Moderate | Cocaine Use Disorder, Severe
-
Tonix Pharmaceuticals, Inc.National Institute on Drug Abuse (NIDA); PremierNot yet recruitingCocaine Use | Cocaine Abuse | Cocaine Adverse Reaction | Cocaine Intoxication | Cocaine Toxicity
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Temple UniversityNational Institute on Drug Abuse (NIDA); University of PennsylvaniaCompletedCocaine-Related Disorders | Cocaine Dependence | Cocaine Abuse | Cocaine AddictionUnited States
-
Baylor College of MedicineNational Institute on Drug Abuse (NIDA)CompletedSubstance Abuse | Cocaine Dependence | Cocaine Abuse | Cocaine AddictionUnited States
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ITAB - Institute for Advanced Biomedical TechnologiesNot yet recruitingCocaine Dependence | Cocaine Use | Cocaine Abuse | NeurotropismItaly
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University of VirginiaRecruitingCocaine Use Disorder | Cocaine Dependence | Ultrasound | Cocaine AbuseUnited States
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University Hospital Center of MartiniqueUnknown
Clinical Trials on Cocaine (IV)
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Embera NeuroTherapeutics, Inc.National Institute on Drug Abuse (NIDA)CompletedCocaine Use DisorderUnited States
-
National Institute on Drug Abuse (NIDA)UnknownCocaine-Related DisordersUnited States
-
Virginia Commonwealth UniversityNational Institute on Drug Abuse (NIDA)CompletedCocaine Use DisorderUnited States
-
Istanbul Training and Research HospitalCompletedAcne Vulgaris | Atrophic Acne Scar | IsotretinoinTurkey
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Biotie Therapies Inc.National Institute on Drug Abuse (NIDA)CompletedCocaine DependenceUnited States
-
New York State Psychiatric InstituteNational Institute on Drug Abuse (NIDA)Completed
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Rigshospitalet, DenmarkCompleted
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Tel-Aviv Sourasky Medical CenterActive, not recruiting
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University of Sao Paulo General HospitalUnknownTreatment | Cocaine Addiction | Transcranial Magnetic StimilationBrazil
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University of Texas Southwestern Medical CenterCompleted