Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

July 19, 2016 updated by: Norwegian University of Science and Technology

The study investigates whether endurance training breathing 100% oxygen gives a additional improvement of maximal oxygen uptake in stable Angina Pectoris patients, compared to training without extra oxygen supplementation. In addition work economy, stroke volume and cardiac perfusion is measured.

The hypothesis of the study is that increased oxygenation of the air increases performance, stroke volume, work economy and cardiac perfusion.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

25

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Norway
      • Trondheim, Norway, 7489
        • Norwegian University of Science and Technology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 75 years (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • stable angina pectoris age 18-75

Exclusion Criteria:

  • unstable angina pectoris
  • Limitations to exercise other than coronary artery disease
  • Participants in other study interventions

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Hypoxic Interval training
4 x 4 minutes interval training with 100% oxygenated air
Behavioral: Hypoxic interval training
4 x 4 minutes interval training in hypoxic air, 3 times per week at 90-95% HR max
Experimental: Normoxic interval training
4 x 4 minutes interval training in normoxic air
Behavioral: Normoxic interval training
4 x 4 minutes normoxic interval training, 3 times per week at 90-95% HR max

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
maximal oxygen uptake
Time Frame: Baseline and post training
Baseline and post training

Secondary Outcome Measures

Outcome Measure
Time Frame
Cardiac perfusion
Time Frame: Baseline and post training
Baseline and post training
work economy
Time Frame: Baseline and post training
Baseline and post training
cardiac output
Time Frame: baseline and post training
baseline and post training

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Norwegian University of Science and Technology

Collaborators

Aarhus University Hospital

Investigators

  • Study Director: Asbjørn Støylen, MD, Norwegian university of sience and technology

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2004

Primary Completion (Actual)

July 1, 2007

Study Completion (Actual)

July 1, 2007

Study Registration Dates

First Submitted

September 15, 2005

First Submitted That Met QC Criteria

September 15, 2005

First Posted (Estimate)

September 16, 2005

Study Record Updates

Last Update Posted (Estimate)

July 20, 2016

Last Update Submitted That Met QC Criteria

July 19, 2016

Last Verified

July 1, 2016

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 094-2004

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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