- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00237562
Feasibility of the Management of Severe Cervical Dysplasia in a Single Visit
May 4, 2006 updated by: University of California, Irvine
Single Visit Cervical Cancer Prevention Program
- Implement a single-visit program (SVP) for cervix cancer prevention in clinics serving a multi-ethnic population of women;
- Set up an efficient system for interpretation of Pap smears for patients in the SVP that will minimize waiting time;
- Determine the follow-up rates and compare them between women assigned to the SVP and a usual care program (UCP);
- Determine satisfaction and compare it between women assigned to the SVP and the UCP;
- Determine the cost-effectiveness and compare it between the SVP and UCP
Study Overview
Status
Completed
Conditions
Intervention / Treatment
Detailed Description
Women were recruited from underserved communities to participate in this single visit cervix cancer project.
Large loop electrosurgical excision procedure (LEEP) was performed on SVP subjects with either a diagnosis of HGSIL/AGUS or suspicion of carcinoma.
All other subjects with abnormal Papanicolaou smears were referred to our abnormal cytology clinics or received care in the community.
Study Type
Interventional
Phase
- Phase 3
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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California
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Orange, California, United States, 92868
- University of California, Irvine
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
Yes
Genders Eligible for Study
Female
Description
Inclusion Criteria:
- Older than 18 years
- No history of invasive cervical cancer
- Not pregnant
Exclusion Criteria:
- Absence of a cervix
- Abnormal vaginal bleeding
- Cervical cancer screening within the previous 12 months
- A known bleeding disorder
- Reluctance to be randomized
- Unwillingness to follow the study protocol
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Prevention
- Allocation: Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Collaborators
Investigators
- Principal Investigator: Alberto Manetta, MD, University of California, Irvine
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
July 1, 1999
Study Registration Dates
First Submitted
October 10, 2005
First Submitted That Met QC Criteria
October 10, 2005
First Posted (Estimate)
October 12, 2005
Study Record Updates
Last Update Posted (Estimate)
May 5, 2006
Last Update Submitted That Met QC Criteria
May 4, 2006
Last Verified
October 1, 2005
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- R01CA076501 (U.S. NIH Grant/Contract)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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National Cancer Institute (NCI)TerminatedCervical Cancer | Cervical Intraepithelial Neoplasia Grade 2 | Cervical Intraepithelial Neoplasia Grade 3United States
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Genexine, Inc.CompletedCervical Intraepithelial Neoplasia 3Korea, Republic of
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Nykode Therapeutics ASATheradex; Vaccibody ASCompletedHigh Grade Cervical Intraepithelial NeoplasiaGermany
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Brookdale University Hospital Medical CenterUnknownCarcinoma in Situ of Uterine Cervix | Cervical Intraepithelial Neoplasias | High Grade Cervical Intraepithelial NeoplasiaUnited States
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BioLeaders CorporationUnknownCervical Intraepithelial Neoplasia Grade 2/3Korea, Republic of
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University Medical Centre MariborRecruitingCervical Intraepithelial Neoplasia Grade 2 | DNA MethylationSlovenia
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Onconix, IncUnknownCervical Cancer | Cervical Intraepithelial Neoplasia III | Cervical Intraepithelial Neoplasia IIUnited States
Clinical Trials on Large loop electrosurgical excision
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Ruhr University of BochumRecruiting
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Oswaldo Cruz FoundationCompletedCervical Intraepithelial NeoplasiaBrazil
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Centre Hospitalier Universitaire, AmiensCompletedPregnancy Complications
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Ontario Clinical Oncology Group (OCOG)Canadian Institutes of Health Research (CIHR)CompletedCervical Intraepithelial NeoplasiaCanada, Brazil
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedCervical CancerUnited States, Canada
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AIDS Clinical Trials GroupNational Institute of Allergy and Infectious Diseases (NIAID)CompletedHIV-1 InfectionPeru, Malawi, South Africa, Zimbabwe, Haiti, Botswana, India
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Oswaldo Cruz FoundationCompletedCervical Intraepithelial NeoplasiaBrazil
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British Columbia Cancer AgencyNational Cancer Institute (NCI)CompletedCervical Cancer | Precancerous ConditionCanada