- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00245687
A Research Study to Test (2) Two Different Types of Feeding Tubes Used in the Intensive Care Unit
March 13, 2014 updated by: Thomas Jefferson University
A Comparative Study of the Tiger Tube Frictional Nasal Jejunal Feeding Tube and the Dubhoff Tube
The purpose of this study is to compare the success rates of two types of feeding tubes, specifically the standard gastric feeding tube to a small bowel feeding tube.
Study Overview
Status
Completed
Intervention / Treatment
Detailed Description
Enteral nutrition has many advantages for critically ill patients including lower incidence of infections and a reduced hospital stay, however it is controversial whether enteral feeding via small bowel feeding tubes offers an advantage over gastric feeding tubes in terms of reducing aspiration risk, improving feeding tolerance or ensuring quicker attainment of nutritional goals.
The advantages of a small bowel feeding tube over a gastric feeding tube is thought to be related to its post pyloric position, however the insertion of small bowel feeding tubes is technically challenging (most studies report a success rate of 15-30%), can take time and has complications not unlike those of the gastric feeding tube.
Our hypothesis is that the small bowel feeding tube offers an advantage to the gastric feeding tube due to its ability to achieve post pyloric placement.
Specifically we chose to compare the standard gastric feeding tube (Dubhoff) to a small bowel feeding tube which offers the advantage of having alternating flaps which allows the gut to drag this tube into the small bowel.
Study Type
Interventional
Enrollment (Anticipated)
60
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Pennsylvania
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Philadelphia, Pennsylvania, United States, 19107
- Thomas Jefferson University Hospital - MRICU
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- all ICU patients requiring enteral nutrition
Exclusion Criteria:
- coagulopathy, esophageal or gastric, surgery, varices, trauma, ulcer, structure, rupture
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
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success in placing feeding tube
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Secondary Outcome Measures
Outcome Measure |
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- rate of reaching nutritional goal, aspiration pneumonia, feeding tolerance, and pre-albumin
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Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: Paul Marik, MD, Thomas Jefferson University
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 2005
Study Completion (Actual)
June 1, 2007
Study Registration Dates
First Submitted
October 26, 2005
First Submitted That Met QC Criteria
October 27, 2005
First Posted (Estimate)
October 28, 2005
Study Record Updates
Last Update Posted (Estimate)
March 14, 2014
Last Update Submitted That Met QC Criteria
March 13, 2014
Last Verified
March 1, 2014
More Information
Terms related to this study
Other Study ID Numbers
- 05U.229
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on no Primary Disease; ICU Patient Who Require Enteral Nutrition
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C. R. BardTerminatedNo Specific Conditions Under Study. Primary Focus: Adult Subjects Who Require PICC PlacementUnited States
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Taipei Medical University WanFang HospitalUnknownICU Ill Patients | Enteral Nutrition FeedingTaiwan
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Second Affiliated Hospital, School of Medicine,...CompletedDevelopment and Validation of a Prediction Model for Refeeding Syndrome in ICU Patients Undergoing Enteral NutritionChina
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Azienda Sanitaria-Universitaria Integrata di UdineCompletedCritical Illness | Constipation | Diarrhea | ICU Acquired Weakness | Enteral Feeding Intolerance | Nutritional Deficiency | Nutritional and Metabolic DiseaseItaly
Clinical Trials on Tiger Tube
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Marcelo Alberto OLIVACompletedAcute Coronary SyndromeArgentina
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Medical University of ViennaCompleted
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University Hospital of PatrasCompleted
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University of OklahomaU.S. Department of EducationCompletedCerebral Palsy | Child, PreschoolUnited States
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Ruijin HospitalNot yet recruitingParkinson Disease | Speech DisordersChina
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Centre Hospitalier le MansNot yet recruitingIntubated Patient Requiring a Gastric TubeFrance
-
Andrew Hendifar, MDCompletedPancreatic Neoplasms | Pancreatic Cancer | Weight Loss | CachexiaUnited States
-
University of ManitobaCompleted
-
Rennes University HospitalCompletedPancreaticoduodenectomy | Digestive System Surgical ProcedureFrance
-
Wakayama Medical UniversityCompletedPancreatic Cancer | Bile Duct Cancer | Pancreatitis | Duodenal Cancer | Ampullary CancerJapan