- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00319293
Efficacy of Metformin in Lean Women With Polycystic Ovary Syndrome
October 10, 2006 updated by: Aarhus University Hospital Skejby
Insulin resistance is an important feature of the polycystic ovary syndrome,and patiens are successfully treated with the insulin sensitizing agent metformin.
The insulin resistance of lean patients with the syndrome is debated.
In this study, we will study the change in insulin resistance, metabolic and hormonal factors after 3 months of metformin treatment in lean PCOS women.
Study Overview
Study Type
Interventional
Enrollment
20
Phase
- Not Applicable
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years to 35 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
Female
Description
Inclusion Criteria:
- PCOS (Rotterdam criteria)
- BMI < 27
- No medication for 3 months
Exclusion Criteria:
- Pregnancy
- Lactation
- Other endocrinologic disease
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Double
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
---|
Insulin resistance
|
Hormonal factors
|
Metabolic factors
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Collaborators
Investigators
- Principal Investigator: Birgitta Trolle, MD, Skejby University Hospital
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Registration Dates
First Submitted
April 26, 2006
First Submitted That Met QC Criteria
April 26, 2006
First Posted (Estimate)
April 27, 2006
Study Record Updates
Last Update Posted (Estimate)
October 11, 2006
Last Update Submitted That Met QC Criteria
October 10, 2006
Last Verified
October 1, 2006
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 160350-2
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Polycystic Ovary Syndrome
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Cairo UniversityCompleted
-
Alexandria UniversityRecruitingPolycystic Ovary Syndrome (PCOS)Egypt
-
Saudi German Hospital - MadinahCompletedPolycystic Ovary Syndrome (PCOS)Saudi Arabia
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Assaf-Harofeh Medical CenterUnknownInfertility | Polycystic OvariesIsrael
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Mansoura UniversityNot yet recruitingPCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
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Riphah International UniversityCompleted
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Dexa Medica GroupCompletedPolycystic Ovary Syndrome (PCOS)Indonesia
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Virginia Commonwealth UniversityEunice Kennedy Shriver National Institute of Child Health and Human Development...TerminatedPolycystic Ovary Syndrome (PCOS)United States
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University Magna GraeciaCompletedInfertility | Polycystic Ovary Syndrome (PCOS)Italy
-
University of CopenhagenCompletedPolycystic Ovary Syndrome (PCOS)Denmark
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