- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00419354
The Impact of Right Ventricular Pacing on Tricuspid Regurgitation
Study Overview
Status
Conditions
Detailed Description
"1" Traditionally, tricuspid regurgitation in the presence of pacemaker is attributed to the physical interference of the valve closure by the electrode.
"2" Right ventricular pacing may be associated with dyssynchrony in contraction of the right ventricular wall (i.e. septum and free wall.
"3" The tricuspid sub-valvar apparatus is anchored to the septum and free wall, thus may be sensitive to dyssynchrony in those wals contraction.
"4" The study hypothesis is that the dyssynchrony in right ventricular contraction, induced by pacing, may increase tricuspid regurgitation grade and that this is a mechanism is independent of the mechanical effect of the electrode on the valve closure.
Study Type
Enrollment (Anticipated)
Contacts and Locations
Study Contact
- Name: Mordehay Vaturi, MD
- Phone Number: 97239376176
- Email: mvaturi@clalit.org.il
Study Locations
-
-
-
Petach Tikva, Israel, 49100
- Recruiting
- Rabin Medical Center
-
Contact:
- Mordehay Vaturi, MD
- Phone Number: 97239376176
- Email: mvaturi@clalit.org.il
-
Principal Investigator:
- Mordehay Vaturi, MD
-
-
Participation Criteria
Eligibility Criteria
Ages Eligible for Study
Accepts Healthy Volunteers
Genders Eligible for Study
Sampling Method
Study Population
Description
Inclusion Criteria:
- Age >18 years
- Permanent pacemaker
Exclusion Criteria:
- Epicardial pacing
- Left ventricular dysfunction
- Organic tricuspid regurgitation
- Bi-ventricular pacemaker
- Atrial fibrillation
- Complete pacemaker dependence
Study Plan
How is the study designed?
Design Details
Collaborators and Investigators
Sponsor
Investigators
- Principal Investigator: Mordehay Vaturi, MD, Department of Cardiology, Rabin Medical Center
Study record dates
Study Major Dates
Study Start
Primary Completion (Anticipated)
Study Completion (Anticipated)
Study Registration Dates
First Submitted
First Submitted That Met QC Criteria
First Posted (Estimate)
Study Record Updates
Last Update Posted (Estimate)
Last Update Submitted That Met QC Criteria
Last Verified
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- 4134 (Other Identifier: Stanford IRB)
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
Clinical Trials on Tricuspid Regurgitation
-
Icahn School of Medicine at Mount SinaiNational Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaboratorsActive, not recruitingTricuspid Regurgitation | Mild Tricuspid Regurgitation | Moderate Tricuspid RegurgitationUnited States, Canada, Germany
-
IRCCS Policlinico S. DonatoRecruitingTricuspid Regurgitation CongenitalItaly
-
Heart Center Leipzig - University HospitalRecruitingFunctional Tricuspid RegurgitationGermany
-
University of ZurichRecruitingSevere Tricuspid RegurgitationSwitzerland
-
P+F Products + Features GmbHCompletedSevere Tricuspid RegurgitationLithuania
-
Innoventric LTDNot yet recruitingTricuspid Regurgitation | Tricuspid Regurgitation Functional
-
Charite University, Berlin, GermanyRecruitingFunctional Tricuspid RegurgitationGermany, Israel
-
Michele De BonisCompleted
-
P+F Products + Features GmbHCompletedSevere Tricuspid RegurgitationSpain, Austria
-
TriFlo Cardiovascular, Inc.Not yet recruitingSymptomatic Severe Tricuspid RegurgitationItaly