Interval Training in Young Healthy Individuals

May 26, 2015 updated by: Norwegian University of Science and Technology

Interval Training: Training, Detraining and Retraining; an Interventional Study

Individuals who participate in regular physical exercise possess a lower prevalence of cardiovascular risk factors such as hypertension, type 2 diabetes, obesity and hypercholesterolemia, and aerobic exercise is therefore considered an important adjuvant therapy in risk factor modification and to promote health.

The main focus of the present study is therefore to detect how rapid it is possible to increase aerobic capacity with interval running exercise.

The hypothesis is that it is possible to improve maximal oxygen uptake faster when increasing training frequency. The total gain in maximal oxygen uptake will however be the same between the two groups when they have performed the same amount of training

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

We will perform aerobic interval training at an intensity of 90-95% of maximum heart rate in healthy individuals. The subjects will be randomly assigned to carry out a total of 24 exercise-sessions, either at 3 times per week or 8 times per week.

The two groups will carry out 24 training sessions before 8 weeks of detraining will provide how rapidly aerobic capacity is lost due to inactivity. After the detraining period a retraining phase is introduced to detect if improvements in aerobic capacity occur more rapidly compared to before the first training period

The subjects will be tested for oxygen uptake, pumping capacity of the heart, blood volume, skeletal muscle enzyme activity, endothelial function.

Study Type

Interventional

Enrollment (Actual)

24

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Norway
      • Trondheim, Norway, 7489
        • NTNU
      • Trondheim, Norway, 7020
        • Norwegian University of Science and Technology

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years to 27 years (Adult)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • BMI<27, non-smokers, train less that 1-2 times per week, VO2max <60 for male and <50 for female.

Exclusion Criteria:

  • Hypertension, diabetes and cardiovascular disease.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: High frequency training
24 interval exercises performed 8 times per week
Behavioral: High frequency training
24 training sessions, 8x weekly, followed by detraining phase 8 weeks, and retraining
Experimental: Normal frequency training
24 interval exercises performed 3 times per week
Behavioral: normal frequence training
24 training sessions, 3x weekly, followed by detraining phase 8 weeks, and retraining

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Oxygen uptake
Time Frame: Before and after the training-, detraining- and retraining-phase
Before and after the training-, detraining- and retraining-phase

Secondary Outcome Measures

Outcome Measure
Time Frame
Cardiac function and skeletal muscle enzyme activity
Time Frame: After training, detraining and retraining
After training, detraining and retraining

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Norwegian University of Science and Technology

Investigators

  • Principal Investigator: Øivind Rognmo, PhD, Norwegian University of Science and Technology
  • Principal Investigator: Ulrik Wisløff, Professor, National Taiwan Normal University

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

September 1, 2008

Primary Completion (Actual)

June 1, 2009

Study Completion (Actual)

December 1, 2009

Study Registration Dates

First Submitted

August 12, 2008

First Submitted That Met QC Criteria

August 12, 2008

First Posted (Estimate)

August 13, 2008

Study Record Updates

Last Update Posted (Estimate)

May 27, 2015

Last Update Submitted That Met QC Criteria

May 26, 2015

Last Verified

May 1, 2015

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 4.2008.1755

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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