- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00966745
Milrinone During Living Donor Hepatectomy
August 26, 2009 updated by: Seoul National University Hospital
Effect of Milrinone During Living Donor Hepatectomy Using a Low Central Venous Pressure Technique
Maintaining a low central venous pressure during living donor hepatectomy is routine practice.
The investigators tried to test the hypothesis that using milrinone to maintain a low central venous pressure (CVP) during is associated with a superior surgical field and less blood loss.
Study Overview
Study Type
Interventional
Enrollment (Actual)
38
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Seoul, Korea, Republic of, 110-744
- Seoul National University Hospital
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
19 years to 55 years (ADULT)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Living liver donors
Exclusion Criteria:
- Donors with concurrent cardiac, pulmonary, and urologic disease
- Hepatectomy performed laparoscopically
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: TREATMENT
- Allocation: RANDOMIZED
- Interventional Model: PARALLEL
- Masking: TRIPLE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Placebo Comparator: placebo
|
|
Active Comparator: milrinone
milrinone infusion
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
condition of surgical field
Time Frame: intraoperative period (from the start of surgery to end of living donor hepatectomy)
|
intraoperative period (from the start of surgery to end of living donor hepatectomy)
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
the use of vasopressor and diuretics to maintain hemodynamic stability and low CVP status, respectively
Time Frame: intraoperative period (from the start of surgery to end of living donor hepatectomy)
|
intraoperative period (from the start of surgery to end of living donor hepatectomy)
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
January 1, 2008
Primary Completion (Actual)
December 1, 2008
Study Completion (Actual)
December 1, 2008
Study Registration Dates
First Submitted
August 13, 2009
First Submitted That Met QC Criteria
August 26, 2009
First Posted (Estimate)
August 27, 2009
Study Record Updates
Last Update Posted (Estimate)
August 27, 2009
Last Update Submitted That Met QC Criteria
August 26, 2009
Last Verified
August 1, 2009
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
Other Study ID Numbers
- mil_living_liver_donor
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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