- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT00988026
Safety and Efficacy Comparison of Minocycline Microgranules Versus Lymecycline in the Treatment of Mild to Moderate Acne (MXMIN-001)
September 30, 2009 updated by: Darier
Safety and Efficacy Comparison of Minocycline Microgranules vs Lymecycline in the Treatment of Mild to Moderate Acne. Randomized, Double Blind, Parallel and Prospective Clinical Trial for 8 Weeks
This is a clinical trial to compare the benefits and possible adverse events of two antibiotic treatments for mild to moderate acne.
It is expected that minocycline microgranules will be more effective than lymecycline with a better adverse events profile.
Study Overview
Status
Unknown
Conditions
Intervention / Treatment
Study Type
Interventional
Enrollment (Anticipated)
168
Phase
- Phase 4
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Contact
- Name: Luis Leobardo Velázquez-Arenas, MD
- Phone Number: (5281)83481465
- Email: leovel2002@yahoo.com.mx
Study Contact Backup
- Name: Jorge Ocampo-Candiani, MD
- Phone Number: (5281)83481465
- Email: jocampo2000@yahoo.com.mx
Study Locations
-
-
Nuevo León
-
Monterrey, Nuevo León, Mexico, 64460
- Recruiting
- Servicio de Dermatología. Hospital " Dr. José Eleuterio González" de la Universidad Autónoma de Nuevo León
-
Contact:
- Blanca Ojeda-Martínez, RN
- Phone Number: (5281)83481465
- Email: blanca_ojeda21@hotmail.com
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
14 years to 30 years (Child, Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- Both gender
- 14 to 30 years old
- Mild to moderate acne
- Face localization
- At least 20 non-inflammatory lesions OR
- At least 15 inflammatory lesions OR
- At least 30 total lesions AND
- Less than 5 nodular lesions
Exclusion Criteria:
- Patients younger than 14 or older than 30 years old
- Less than 20 non-inflammatory lesions OR
- Less than 15 inflammatory lesions OR
- Less than 30 total lesions
- Patients with severe acne
- More than 5 nodular lesions OR
- More than 50 inflammatory lesions OR
- More than 125 total lesions
- Pregnant women
- Lactating women
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Treatment
- Allocation: Randomized
- Interventional Model: Parallel Assignment
- Masking: Triple
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
Experimental: Minocycline 100 mg
Minocycline
|
Minocycline 100 mg OD per mouth for 8 weeks.
Lymecycline 300 mg OD per mouth for 8 weeks.
|
Active Comparator: Lymecycline 300 mg
Group B: Lymecycline
|
Minocycline 100 mg OD per mouth for 8 weeks.
Lymecycline 300 mg OD per mouth for 8 weeks.
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Number of inflammatory and non-inflammatory acne lesions
Time Frame: 8 weeks
|
8 weeks
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
Incidence of local and systemic adverse events
Time Frame: 8 weeks
|
8 weeks
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
June 1, 2009
Primary Completion (Anticipated)
February 1, 2010
Study Completion (Anticipated)
April 1, 2010
Study Registration Dates
First Submitted
September 30, 2009
First Submitted That Met QC Criteria
September 30, 2009
First Posted (Estimate)
October 1, 2009
Study Record Updates
Last Update Posted (Estimate)
October 1, 2009
Last Update Submitted That Met QC Criteria
September 30, 2009
Last Verified
September 1, 2009
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- MXMIN-001
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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