Prevention of Stroke and Dementia in Primary Care (INVADE)

February 16, 2012 updated by: Technical University of Munich

Intervention Project of Cerebrovascular Diseases and Dementia in the District of Ebersberg

In Western Countries, stroke and dementia are the main causes of long-term disability, dependency, and nursing home admission. Due to demographic trends a continuous increase of patient numbers can be expected.

There is growing evidence that vascular risk factors which are implicated in the etiology of stroke also play important etiologic roles in both vascular dementia and Alzheimer disease. The present project is aimed at the reduction of stroke and dementia by means of a systematic detection and subsequent treatment of vascular risk factors by the family doctor based on established guidelines.

Study Overview

Status

Terminated

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Actual)

3908

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
      • Munich, Germany, D-81675
        • Depts. of Psychiatry and Neurology, Technische Universität München

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

55 years and older (ADULT, OLDER_ADULT)

Accepts Healthy Volunteers

Yes

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Age 55 years or over
  • Member of a particular health insurance plan (AOK)
  • Resident of the district of Ebersberg

Exclusion Criteria:

  • None

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: PREVENTION
  • Allocation: NON_RANDOMIZED
  • Interventional Model: SINGLE_GROUP
  • Masking: NONE

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
EXPERIMENTAL: Evidence-based treatment, lifestyle counseling
Other: Systematic detection of vascular risk factors and subsequent evidence-based treatment

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
Incidence of long-term care disability
Time Frame: 8 years
8 years
Incidence of stroke
Time Frame: 8 Years
8 Years

Secondary Outcome Measures

Outcome Measure
Time Frame
Reduction of cardiovascular risk factors
Time Frame: 8 years
8 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Technical University of Munich

Collaborators

Bayer
Organon
Sanofi-Synthelabo
AOK Bayern
Ratiopharm GmbH
Berlin-Chemie Menarini
Teva Pharma GmbH
Stiftung Deutsche Schlaganfall-Hilfe

Investigators

  • Principal Investigator: Horst Bickel, PhD, Dept. of Psychiatry, Technical University of Munich

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Helpful Links

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2001

Primary Completion (ACTUAL)

December 1, 2008

Study Completion (ACTUAL)

March 1, 2010

Study Registration Dates

First Submitted

April 19, 2010

First Submitted That Met QC Criteria

April 19, 2010

First Posted (ESTIMATE)

April 21, 2010

Study Record Updates

Last Update Posted (ESTIMATE)

February 20, 2012

Last Update Submitted That Met QC Criteria

February 16, 2012

Last Verified

April 1, 2010

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 080250hb

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Stroke

Clinical Trials on Systematic detection of vascular risk factors and subsequent evidence-based treatment

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Turkmenistan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe