- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01177631
Proteomic Analysis of Human Hepatocellular Carcinoma
February 4, 2016 updated by: Meng-Tzu Weng, Far Eastern Memorial Hospital
Proteomic Analysis of Human Hepatocellular Carcinoma Associated With Portal Vein Thrombosis
This is a pilot study to evaluate the difference between the protein expression between hepatocellular carcinoma and tumor with vessel invasion in Asian patients with hepatocellular carcinoma.
Study Overview
Study Type
Interventional
Enrollment (Actual)
5
Phase
- Not Applicable
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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Taipei, Taiwan, 220
- Far Eastern Memorial Hospital
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 75 years (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
Arm A: Hepatocellular carcinoma with vessel invasion:
- hepatocellular carcionoma, pathologic diagnosed.
- image documented vessel invasion, including portal vein thrombosis
- eligible for surgical intervension.
Arm B: hepatocellular carcinoma without vessel invasion:
- hepatocellular carcinoma, pathologic diagnosed or clinical diagnosed according to EASL criteria.
- no vessel invasion on image.
Arm C: Healthy hepatitis carrier:
- patients age >18 years old with hepatitis B or C
- normal liver function.
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: Basic Science
- Allocation: Non-Randomized
- Interventional Model: Single Group Assignment
- Masking: None (Open Label)
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Recurrence
Time Frame: one year
|
Evidence of clinically definite vascular invasion of hepatocellular carcinoma.
Confirmed by operation.
Compare the proteomic expression of tumor, non-tumor ans tumor tissue in vascular part.
|
one year
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
February 1, 2009
Primary Completion (Actual)
January 1, 2010
Study Completion (Actual)
January 1, 2010
Study Registration Dates
First Submitted
June 2, 2009
First Submitted That Met QC Criteria
August 5, 2010
First Posted (Estimate)
August 9, 2010
Study Record Updates
Last Update Posted (Estimate)
February 5, 2016
Last Update Submitted That Met QC Criteria
February 4, 2016
Last Verified
February 1, 2016
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 97068
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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