Effect of Exercise With or Without Breakfast, on Metabolism, Appetite and Cognition

The Interactive Effect of Breakfast Consumption and Exercise on Metabolism, Appetite and Cognitive Function

The purpose of this study is to assess the effect of eating breakfast in combination with exercise on fat usage, appetite and brain performance later in the day.

Study Overview

• Status: Completed
• Conditions: Energy Balance,; Appetite,; Cognitive Function.
• Intervention / Treatment: Drug: Breakfast & exercise

• Study Type: Interventional
• Enrollment (Actual): 12
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United Kingdom
  • Tyne and Wear
    • Newcastle Upon Tyne, Tyne and Wear, United Kingdom, NE1 8ST
      • Brain, Performance and Nutrition Centre, Northumbria University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 45 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Male
• Aged 18-45 years
• BMI 18.5-24.9 kg/m2
• Physically active: able to run for 1 h at a moderate pace
• Healthy

Exclusion Criteria:

• Smokers
• Food allergies
• Metabolic disorders
• Restrained eaters (equivalent of >7 for restrained on TFEQ)
• Consuming herbal/dietary supplements
• History of head trauma
• Learning difficulties
• ADHD
• Dyslexia
• History of migraines
• Gastric problems

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Prevention
• Allocation: Randomized
• Interventional Model: Crossover Assignment
• Masking: None (Open Label)

Number of Arms

4

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Breakfast & exercise	Drug: Breakfast & exercise; 1859 kJ breakfast vs fast, exercise at 60% maximum aerobic capacity to expend 1859 kJ.
Experimental: Breakfast & no exercise	Drug: Breakfast & exercise; 1859 kJ breakfast vs fast, exercise at 60% maximum aerobic capacity to expend 1859 kJ.
Experimental: No breakfast & exercise	Drug: Breakfast & exercise; 1859 kJ breakfast vs fast, exercise at 60% maximum aerobic capacity to expend 1859 kJ.
No Intervention: No breakfast & no exercise

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Energy balance	Energy balance (kJ/kcal) will be assessed by an ad libitum test meal provided at 5 h minus energy expenditure estimated by indirect calorimetry.	24 h

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Blood glucose		1.5 h area under the curve, post-consumption of a liquid snack
Serum insulin		1.5 h area under the curve, post-consumption of a liquid snack
Subjective appetite ratings	Participants will be asked to complete visual analogue scales (VAS).	1.5 h area under the curve, post-consumption of a liquid snack and following an ad libitum test meal
Cognitive function measurements	Reaction time, short-term memory, speed of processing, attention.	1.5 h area under the curve, post-consumption of a liquid snack and following an ad libitum test meal
Mood	Participants will be asked to complete visual analogue scales (VAS).	1.5 h area under the curve, post-consumption of a liquid snack and following an ad libitum test meal
Energy expenditure	Measured by indirect calorimetry	1.5 h mean following a liquid snack

Collaborators and Investigators

• Sponsor: Northumbria University
• Investigators: Principal Investigator: Emma J Stevenson, PhD, Northumbria University

Study record dates

Study Major Dates

• Study Start: October 1, 2010
• Primary Completion (Actual): July 1, 2011
• Study Completion (Actual): July 1, 2011

Study Registration Dates

• First Submitted: October 12, 2010
• First Submitted That Met QC Criteria: October 26, 2010
• First Posted (Estimate): October 27, 2010

Study Record Updates

• Last Update Posted (Estimate): May 4, 2012
• Last Update Submitted That Met QC Criteria: May 2, 2012
• Last Verified: May 1, 2012

More Information

Terms related to this study

• Other Study ID Numbers: 32W3