Neuroplasticity-oriented Cognitive Intervention in Early Onset and First Admission Schizophrenia

December 15, 2014 updated by: Prof. Dr. Brigitte Rockstroh, University of Konstanz
The purpose of this study is to reveal the specific effects of computer-aided cognitive training on course and rehabilitation in early onset schizophrenia

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Impairment in cognitive functions is one of the main symptoms in schizophrenia and is currently one of the challenges in the treatment of the disease. We examine the beneficial effect of computer-aided training program on course and rehabilitation of young psychotic patients with early onset psychosis. In addition we develop predictors for the course of disorder from neuroimaging data.

Study Type

Interventional

Enrollment (Actual)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Germany
    • Baden Wuerttemberg
      • Konstanz, Baden Wuerttemberg, Germany, 78464
        • University Konstanz

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

17 years to 37 years (Child, Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Early Onset Psychosis

Exclusion Criteria:

  • Chronicity
  • Insufficient German skills

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Prevention
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Cognitive Training
Brain Fitness Training, Posit Science SF
Behavioral: Brain Fitness Training, Posit Science SF
Computer aided cognitive training based on principles of neuroplasticity

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
change from baseline at post-training and at 3-months and at 7-months follow-up in each of the following outcome measures: neuropsychological test performance (MCCCB), GAF, PANSS, MEG event-related potentials (M50), alpha activity
Time Frame: baseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up
baseline, post-training (training duration 4 weeks), 3-month follow-up, 7-month follow-up

Secondary Outcome Measures

Outcome Measure
Time Frame
change from baseline in GAF score at 3-months and 7-moths follow-up
Time Frame: baseline, 3-months follow-up, 7-months follow-up
baseline, 3-months follow-up, 7-months follow-up

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

University of Konstanz

Investigators

  • Study Director: Brigitte S Rockstroh, Prof. Dr., University of Konstanz

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

January 1, 2012

Primary Completion (Actual)

December 1, 2014

Study Completion (Actual)

December 1, 2014

Study Registration Dates

First Submitted

January 22, 2013

First Submitted That Met QC Criteria

January 30, 2013

First Posted (Estimate)

February 1, 2013

Study Record Updates

Last Update Posted (Estimate)

December 16, 2014

Last Update Submitted That Met QC Criteria

December 15, 2014

Last Verified

December 1, 2014

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • FP16963311

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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