- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT01840514
Cardiac Functions in Living Donor Liver Transplant Recipients. An Echocardiographic Study.
October 4, 2013 updated by: Amr Mohamed Yassen, Mansoura University
The stress of orthotopic living donor liver transplantation in patients with cirrhosis could induce worsening of an already recorded myocardial dysfunction or may be associated with a new myocardial dysfunction in patients previously having normal myocardial functions, therefore this study will be designed for intra-operative detection of new onset ventricular dysfunction or worsening of already diagnosed ventricular dysfunction in living donor liver transplant recipient and the possible contribution of several hemodynamic and oxygenation parameters in the generation of any cardiovascular function impairment will be also investigated and to determine the impact of ventricular dysfunction on early (7 PO days) graft function, 28 days survival and patient outcomes.
Study Overview
Status
Unknown
Conditions
Study Type
Observational
Enrollment (Anticipated)
60
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
Dakahlia
-
Mansoura, Dakahlia, Egypt, 35511
- Recruiting
- Liver transplantation project - Gastroenterology surgical center - Mansoura university
-
Sub-Investigator:
- Amr M Yassen, MD
-
Mansoura, Dakahlia, Egypt, 35511
- Recruiting
- Liver transplantation program - Gastroenterology surgical center
-
Contact:
- Waleed R alsarraf, MD
- Phone Number: +201222322727
- Email: welsarraf@yahoo.com
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Principal Investigator:
- Amr Yassen, MD
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years to 60 years (Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
recipient of living donor liver
Description
Inclusion Criteria:
- all adult recipient
Exclusion Criteria:
- massive blood transfusion
- grade III esophageal varices
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
hemodynamic monitoring
Time Frame: intraoperative
|
intraoperative
|
Secondary Outcome Measures
Outcome Measure |
Time Frame |
---|---|
graft function
Time Frame: 7 days
|
7 days
|
Other Outcome Measures
Outcome Measure |
Time Frame |
---|---|
survival
Time Frame: 28 days
|
28 days
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Investigators
- Principal Investigator: amr yassen, MD, Liver transplant program, mansoura faculty of medicine
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
December 1, 2012
Primary Completion (Anticipated)
April 1, 2015
Study Completion (Anticipated)
September 1, 2015
Study Registration Dates
First Submitted
April 23, 2013
First Submitted That Met QC Criteria
April 24, 2013
First Posted (Estimate)
April 25, 2013
Study Record Updates
Last Update Posted (Estimate)
October 8, 2013
Last Update Submitted That Met QC Criteria
October 4, 2013
Last Verified
October 1, 2013
More Information
Terms related to this study
Keywords
Other Study ID Numbers
- 1982
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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