A Retrospective Chart Review of Thirty Three Children Who Have Received Clinical Treatment With Either Romiplostim or Eltrombopag From 2009-2013

A Retrospective Chart Review of Thirty Three Children Who Have Received Clinical Treatment With Either Romiplostim or Eltrombopag From 2009-2013

Sponsors

Lead Sponsor: Weill Medical College of Cornell University

Collaborator: Children’s Hospital of Orange County

Source Weill Medical College of Cornell University
Brief Summary

This is a retrospective analysis of children (≤21years old) who received clinical treatment with either Romiplostim or Eltrombopag at 2 medical centers from 2009-2013. The children included in this study were from Weill Medical College of Cornell University, New York, New York and Children's Hospital Orange County, Orange, California

Overall Status Completed
Start Date January 2012
Completion Date June 2013
Primary Completion Date June 2013
Study Type Observational
Primary Outcome
Measure Time Frame
Platelet count greater than or = to 50,000 on two consecutive weeks
Secondary Outcome
Measure Time Frame
An increase in platelets greater than or = to 20,000 over baseline. On two consecutive weeks
Enrollment 33
Condition
Eligibility

Sampling Method: Probability Sample

Criteria:

Inclusion Criteria:

1. All patients in this study had received prior treatments before the start of TPO treatment including corticosteroids, IVIG, IV anti-D, and/or Rituximab.

Exclusion Criteria:

1. Children who do not have ITP

Gender: All

Minimum Age: 19 Months

Maximum Age: 21 Years

Healthy Volunteers: No

Overall Official
Last Name Role Affiliation
James B Bussel, M.D Principal Investigator Weill Cornell Medicine
Location
Facility: Weill Cornell Medical College
Location Countries

United States

Verification Date

January 2017

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Condition Browse
Arm Group

Label: Romiplostim group

Label: Eltrombopag group

Patient Data No
Study Design Info

Observational Model: Case-Only

Time Perspective: Retrospective

Source: ClinicalTrials.gov