Non-Invasive Optical Spectroscopic Methods for Dehydration Identification in Marathon Trainees

Dehydration can result from exposure to harsh environments including hot and dry desert climates. Soldiers and non-military workers are frequently required to work in hot, dry conditions, and dehydration can be productivity limiting and life threatening if unrecognized.

Study Overview

• Status: Withdrawn
• Conditions: Dehydration
• Intervention / Treatment: Device: Non-Invasive Optical Spectroscopic

Detailed Description

The research can use low power laser technology to take measurements of muscle tissue water content in volunteers before and after marathon training runs to detect dehydration. Two slightly different devices can be used to detect dehydration. 1). diffuse optical spectroscopy and 2). spatial frequency domain imaging-modulated imaging The researchers can determined by use other methods to assess the level of dehydration status in runners. These methods will include taking weight and temperature before and after run, skin-fold measurements pre and post run, and obtaining saliva samples from before and after run. The researchers can determine the study use non-invasive, laser light technology measure tissue water concentrations, as an indicator of dehydration.

• Study Type: Observational

Contacts and Locations

Study Locations

• United States
  • California
    • Irvine, California, United States, 92612
      • Beckman Laser Institute University of California Irvine

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 60 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Study population are the volunteers who are training for a marathon individually or under the guidance of the Leukemia Society Team in Training, the American Heart Association, or similar groups. These organizations run programs that include providing group-training situations for individuals interested in preparing for a marathon while participating in fund raising efforts.

Description

Inclusion Criteria:

• male female ages of 18 and 60
• training for a marathon

Exclusion Criteria:

1. Poorly controlled diabetes mellitus
2. Diabetes insipidus (excessive urination of water) as diagnosed by your physician
3. disorder of the intestine
4. Irritable bowel syndrome with excessive diarrhea, as diagnosed by a physician
5. Congestive heart failure and subsequent use of a diuretic "water pill" to remove excess water from the body
6. Have poor kidney function
7. Have been diagnosed with hyperthyroidism/hypothyroidism by your physician

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Dehydration; Non-Invasive Optical Spectroscopic monitoring method for dehydration	Device: Non-Invasive Optical Spectroscopic; Non-Invasive Optical Spectroscopic

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Hydration	Marathon Trainees	up to 4 weeks

Collaborators and Investigators

• Sponsor: University of California, Irvine
• Collaborators: Beckman Laser Institute University of California Irvine
• Investigators: Principal Investigator: Matthew Brenner, MD, Beckman Laser Institute

Study record dates

Study Major Dates

• Study Start: August 1, 2013
• Primary Completion (Anticipated): August 1, 2018
• Study Completion (Anticipated): August 1, 2018

Study Registration Dates

• First Submitted: August 13, 2013
• First Submitted That Met QC Criteria: November 5, 2013
• First Posted (Estimate): November 13, 2013

Study Record Updates

• Last Update Posted (Actual): November 1, 2022
• Last Update Submitted That Met QC Criteria: October 28, 2022
• Last Verified: October 1, 2022

More Information

Terms related to this study

• Keywords: Dehydration
• Additional Relevant MeSH Terms: Pathologic Processes; Metabolic Diseases; Water-Electrolyte Imbalance; Dehydration
• Other Study ID Numbers: 20129075