Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis.

Evaluation of Locomotor Activity Before and After Total Hip Replacement in Patients With Hip Osteoarthritis. Use of Ganglion and Neural Network Techniques to Identify Objective Criteria for the Success of Arthroplasty

The investigators believe that the application of non-linear methods of analysis using the ganglion and neural network technique will make it possible to analyse all of the complex data obtained in patients with hip osteoarthritis before and then after total hip replacement, and should allow us to identify a combination of objective variables to classify the surgery as " successful " or " unsuccessful ".

To this end, the study will take place as follows:

Step 1: Screening, and inclusion. Step 2: Evaluation of the hip osteoarthritis and analysis of locomotor activity Step 3: Total hip replacement Step 4: Clinical evaluation of locomotor activity carried out between 6 months and 1 year after the THR Step 5: Data analysis

Study Overview

• Status: Completed
• Conditions: Hip Osteoarthritis; Indication for Total Hip Replacement
• Intervention / Treatment: Other: Analysis of movement before total hip replacement; Other: Analysis of movement after total hip replacement

• Study Type: Observational
• Enrollment (Actual): 202

Contacts and Locations

Study Locations

• France
  • Dijon, France, 21079
    • CHU de Dijon

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 25 years to 85 years (Adult, Older Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

hip osteoarthritis indication for total hip replacement

Description

Inclusion Criteria:

Control group:

• Subjects who have provided written informed consent
• Subjects covered by the national health insurance scheme
• Men or women aged between 25 and 85 years
• able to understand simple instructions and packaging instructions and able to give informed consent

Patients group:

• Patients who have provided written informed consent
• Patients covered by the national health insurance scheme
• Men or women aged between 25 and 85 years
• able to understand simple instructions and packaging instructions and to give their informed consent
• Suffering from hip osteoarthritis defined according to ACR criteria
• Most recent radiography examination less than 6 months earlier
• Radiological stage II, III or IV hip osteoarthritis according to the Kellgren and Lawrence classification
• Presenting with an indication for total hip replacement, according to the surgeon's usual criteria

Exclusion Criteria:

Control group:

• Hip osteoarthritis or other arthrosis in the lower limbs
• Pregnant or breast-feeding women
• Disorders that may interfere with gait analysis
• Disorder that may be destabilized by gait analysis
• Neurological disease and/or motor neuron disease

Patients group:

• Contra-indication for total hip replacement
• Repeat surgery for total hip replacement
• Impossibility to use a standard implant
• Pregnant or breast-feeding women
• Inflammatory flare of the hip osteoarthritis
• Disorder that may interfere with gait analysis
• Disorder that may be destabilized by gait analysis
• Rapidly destructive hip osteoarthritis
• Neurological disease and/or motor neuron disease
• Hip dysplasia requiring THR to be completed using a graft

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Controls	Other: Analysis of movement before total hip replacement
Patients	Other: Analysis of movement before total hip replacement; Other: Analysis of movement after total hip replacement

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
Degree of patient statisfaction	Before and between 6 months and 1 year after total hip replacement

Collaborators and Investigators

• Sponsor: Centre Hospitalier Universitaire Dijon

Publications and helpful links

General Publications

• Moissenet F, Naaim A, Ornetti P, Bourredjem A, Binquet C, Morisset C, Gouteron A, Maillefert JF, Laroche D. Is the Pelvis-Thorax Coordination a Valuable Outcome Instrument to Assess Patients With Hip Osteoarthritis? Front Bioeng Biotechnol. 2020 Jan 23;7:457. doi: 10.3389/fbioe.2019.00457. eCollection 2019.

Study record dates

Study Major Dates

• Study Start (Actual): January 7, 2010
• Primary Completion (Actual): December 11, 2014

Study Registration Dates

• First Submitted: January 17, 2014
• First Submitted That Met QC Criteria: January 20, 2014
• First Posted (Estimate): January 23, 2014

Study Record Updates

• Last Update Posted (Actual): May 3, 2019
• Last Update Submitted That Met QC Criteria: May 2, 2019
• Last Verified: May 1, 2019

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Arthritis; Osteoarthritis; Osteoarthritis, Hip
• Other Study ID Numbers: TROUILLOUD AOI 2007