Downhill Walking Training in COPD

April 11, 2014 updated by: Thierry Troosters, KU Leuven

Downhill Walking to Enhance Training Effects in Patients With COPD

This randomized control trial will investigate whether a modality that generates more contractile muscle fatigue with lower ventilatory requirements render better results after a 12-week exercise training program in subjects with COPD.

Subjects will be randomized to either exercise in a training program including downhill walking or to exercise in a training program including conventional walking.

Study Overview

Status

Unknown

Conditions

Intervention / Treatment

Study Type

Interventional

Enrollment (Anticipated)

42

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Belgium
    • Vl-Brabant
      • Leuven, Vl-Brabant, Belgium, 3000
        • Recruiting
        • University Hospitals Leuven
        • Principal Investigator:
          • Thierry Troosters, PhD
        • Sub-Investigator:
          • Carlos Augusto Camillo, MSc
        • Principal Investigator:
          • Wim Janssens, MD, PhD

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Description

Inclusion Criteria:

  • Patients with a primary diagnosis of COPD according to internationally accepted guidelines
  • Patients referred to the outpatient PR program of Gasthuisberg University Hospital(Leuven, Belgium)

Exclusion Criteria:

  • Any underlying disease or musculoskeletal limitation that could impair the ability to perform any of the exercise training modalities
  • Absence of exacerbations in the previous month before entering the present study
  • Patients included on the waiting list for lung transplantation

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: Randomized
  • Interventional Model: Parallel Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Downhill walking training
Exercise training including treadmill walking with a negative inclination.
Other: Downhill walking training
Walk on a treadmill with a negative inclination.
Active Comparator: Conventional walking training
Exercise training including treadmill walking without inclination. Possible to progress training intensity with positive inclinations.
Other: Conventional walking training
Walk on a treadmill without inclination. Possible to progress training intensity with positive inclinations

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Time Frame
changes in 6-minute walking distance
Time Frame: changes from baseline to Week 12
changes from baseline to Week 12

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

KU Leuven

Collaborators

Conselho Nacional de Desenvolvimento Científico e Tecnológico
Research Foundation Flanders

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

April 1, 2014

Primary Completion (Anticipated)

April 1, 2015

Study Registration Dates

First Submitted

April 8, 2014

First Submitted That Met QC Criteria

April 11, 2014

First Posted (Estimate)

April 15, 2014

Study Record Updates

Last Update Posted (Estimate)

April 15, 2014

Last Update Submitted That Met QC Criteria

April 11, 2014

Last Verified

April 1, 2014

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ML10278

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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