Adaptation in Lower Extremity After 3 Running Days, With a Group Trained by Eccentric Overload

Differences in Muscle (Vastus Laterals and Gastrocnemius Medialis) and Tendon Adaptation (Patellar and Achilles) in Lower Extremity After 3 Running Days With a Group Trained by Eccentric Overload, Measured by Ultrasound and Thermography

This study evaluates the changes in muscles and tendons in the lower limb after an intervention of fatigue during 3 consecutive days between trained or not healthy subjects. One of the 2 groups received training by eccentric overload previously.

Study Overview

• Status: Completed
• Conditions: Sports Injuries
• Intervention / Treatment: Other: Control; Other: Eccentric Overload

Detailed Description

Changes in muscle and tendon tissues, due to exercise, could determine in the future the possibility of an injury. Understand the changes in the mechanical tissues is a key tool for prevention.

The evaluation of the thickness and area in tendons, the existence of new vessels within the tendon, muscle pennation angle or thermography are tools that have been widely used to detect these changes.

Running is one of the activities that can cause more muscle-tendon injuries, specially overuse injuries. However, the eccentric exercise suggest to make some adaptations in different tissues that may be beneficial to prevent damage after exercise.

• Study Type: Interventional
• Enrollment (Actual): 19
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Spain
  • Zaragoza
    • Villanueva de Gallego, Zaragoza, Spain, 50830
      • Universidad San Jorge

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Healthy subjects that performs any sport usually
• Subjects that never have made eccentric training will be included.
• Subjects must be willing to perform the procedure
• Sign informed consent

Exclusion Criteria:

• Subjects enrolled with lower limb pathology in last 6 months
• Subjects that don´t complete all the procedure will be excluded.

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Screening
• Allocation: Non-Randomized
• Interventional Model: Parallel Assignment
• Masking: Single

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Active Comparator: Eccentric; 6 Weeks Training with eccentric Overload (Squat with Yoyo Technology) 3 Consecutive Days Running 1 hour at 80% of Maximus Heart Rate	Other: Control; 3 Consecutive Days Running at 80% Maximus Heart Rate; Other: Eccentric Overload; Training with Eccentric Overload (Squat in Yoyo Technology) during 6 Weeks 3 Consecutive Days Running at 80% Maximus Heart Rate
Active Comparator: Control; 3 Consecutive Days Running 1 hour at 80% of Maximus Heart Rate	Other: Control; 3 Consecutive Days Running at 80% Maximus Heart Rate

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Composite Measure with Ultrasound in Tendons and Muscles	Ultrasound in Patellar and Achilles Tendon, to measure area, thickness and new blood vessels with Doppler. Ultrasound in Vastus Lateralis and Gastrocnemius Medialis to measure pennation angle	Change from Baseline in tendon structure, an expected average of 3 days of running

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Temperature changes in Patellar and Achilles Tendon as assessed by thermography	Thermography in Patellar and Achilles Tendon in order to measure changes in temperature os these areas of interest	Change from Baseline in tendon structure after 3 days of running. Just immediately and 10 minutes after intervention

Collaborators and Investigators

• Sponsor: Universidad San Jorge
• Collaborators: University of Jaen
• Investigators: Study Director: César Berzosa, Ph.D, Universidad San Jorge

Study record dates

Study Major Dates

• Study Start: June 1, 2015
• Primary Completion (Actual): June 1, 2015
• Study Completion (Actual): August 1, 2015

Study Registration Dates

• First Submitted: May 27, 2015
• First Submitted That Met QC Criteria: June 22, 2015
• First Posted (Estimate): June 25, 2015

Study Record Updates

• Last Update Posted (Estimate): August 21, 2015
• Last Update Submitted That Met QC Criteria: August 20, 2015
• Last Verified: June 1, 2015

More Information

Terms related to this study

• Keywords: Ultrasound; Running; Muscle; Thermography; Eccentric; Tendon
• Additional Relevant MeSH Terms: Wounds and Injuries; Athletic Injuries
• Other Study ID Numbers: TF_US20015