Adaptation in Lower Extremity After 3 Running Days, With a Group Trained by Eccentric Overload

August 20, 2015 updated by: Universidad San Jorge

Differences in Muscle (Vastus Laterals and Gastrocnemius Medialis) and Tendon Adaptation (Patellar and Achilles) in Lower Extremity After 3 Running Days With a Group Trained by Eccentric Overload, Measured by Ultrasound and Thermography

This study evaluates the changes in muscles and tendons in the lower limb after an intervention of fatigue during 3 consecutive days between trained or not healthy subjects. One of the 2 groups received training by eccentric overload previously.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

Changes in muscle and tendon tissues, due to exercise, could determine in the future the possibility of an injury. Understand the changes in the mechanical tissues is a key tool for prevention.

The evaluation of the thickness and area in tendons, the existence of new vessels within the tendon, muscle pennation angle or thermography are tools that have been widely used to detect these changes.

Running is one of the activities that can cause more muscle-tendon injuries, specially overuse injuries. However, the eccentric exercise suggest to make some adaptations in different tissues that may be beneficial to prevent damage after exercise.

Study Type

Interventional

Enrollment (Actual)

19

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Spain
    • Zaragoza
      • Villanueva de Gallego, Zaragoza, Spain, 50830
        • Universidad San Jorge

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

Male

Description

Inclusion Criteria:

  • Healthy subjects that performs any sport usually
  • Subjects that never have made eccentric training will be included.
  • Subjects must be willing to perform the procedure
  • Sign informed consent

Exclusion Criteria:

  • Subjects enrolled with lower limb pathology in last 6 months
  • Subjects that don´t complete all the procedure will be excluded.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Screening
  • Allocation: Non-Randomized
  • Interventional Model: Parallel Assignment
  • Masking: Single

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Active Comparator: Eccentric
6 Weeks Training with eccentric Overload (Squat with Yoyo Technology) 3 Consecutive Days Running 1 hour at 80% of Maximus Heart Rate
Other: Control
3 Consecutive Days Running at 80% Maximus Heart Rate
Other: Eccentric Overload
Training with Eccentric Overload (Squat in Yoyo Technology) during 6 Weeks 3 Consecutive Days Running at 80% Maximus Heart Rate
Active Comparator: Control
3 Consecutive Days Running 1 hour at 80% of Maximus Heart Rate
Other: Control
3 Consecutive Days Running at 80% Maximus Heart Rate

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Composite Measure with Ultrasound in Tendons and Muscles
Time Frame: Change from Baseline in tendon structure, an expected average of 3 days of running

Ultrasound in Patellar and Achilles Tendon, to measure area, thickness and new blood vessels with Doppler.

Ultrasound in Vastus Lateralis and Gastrocnemius Medialis to measure pennation angle
Change from Baseline in tendon structure, an expected average of 3 days of running

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Temperature changes in Patellar and Achilles Tendon as assessed by thermography
Time Frame: Change from Baseline in tendon structure after 3 days of running. Just immediately and 10 minutes after intervention
Thermography in Patellar and Achilles Tendon in order to measure changes in temperature os these areas of interest
Change from Baseline in tendon structure after 3 days of running. Just immediately and 10 minutes after intervention

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Universidad San Jorge

Collaborators

University of Jaén

Investigators

  • Study Director: César Berzosa, Ph.D, Universidad San Jorge

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

June 1, 2015

Primary Completion (Actual)

June 1, 2015

Study Completion (Actual)

August 1, 2015

Study Registration Dates

First Submitted

May 27, 2015

First Submitted That Met QC Criteria

June 22, 2015

First Posted (Estimate)

June 25, 2015

Study Record Updates

Last Update Posted (Estimate)

August 21, 2015

Last Update Submitted That Met QC Criteria

August 20, 2015

Last Verified

June 1, 2015

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • TF_US20015

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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