G-CREDIT (Gangnam-Cohort for Risk Evaluation of Diabetes and Impaired Glucose Tolerance)

The prevalence of type 2 diabetes has consistently increased and type 2 diabetes can cause many types of vascular complications. Diabetes develops due to glucose intolerance. Early detection and intervention in the stage of glucose intolerance makes it afford to prevent overt diabetes and its complications. This study was designed to make a cohort of korean patients with glucose intolerance to construct a long term database about clinical characteristics of these patients.

Study Overview

• Status: Not yet recruiting
• Conditions: Type 2 Diabetes; Impaired Glucose Intolerance

• Study Type: Observational
• Enrollment (Anticipated): 500

Contacts and Locations

• Study Contact: Name: Chul Woo Ahn, MD; Phone Number: 82-02-2019-3339; Email: acw@yuhs.ac

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years to 100 years (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Non-Probability Sample

Study Population

Patients with either type 2 diabetes or impaired glucose toloerance who are older than 20 years old and have attended Gangnam Severance hospital for regular follow up.

Description

Inclusion Criteria:

1. Patients older than 20 years old who has visited Gangnam severance hospital since January 2007.
2. Patients with either diabetes or impaired glucose tolerance
3. Patients with at least 6 months of follow-up period

Exclusion Criteria:

1. Patients with gestational diabetes, any active stage of cancer and severe disability

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort
Diabetes and Impaired glucose Tolerance (G-CREDIT); Patients with either type 2 diabetes or impaired glucose tolerance who are older than 20 years old and have attended Gangnam Severance hospital for regular follow up.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Life style assessment - Past medical history - Smoking, alcohol history - Sleep, exercise, daily activity check - Diet - Reproductive status (Women only) - Socioeconomic status	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Past medical history	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Smoking, alcohol history	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Sleep, exercise, daily activity check	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Diet	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Reproductive status (Women only)	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Socioeconomic status	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Anthropometric measurements : Height, weight, waist circumference, pulse rate, blood pressure	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
SMA, TG, HDL, LDLM apoA, apoB	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
PC2hrs, HbA1C, Insulin, C-peptide (AC, PC2hr), hs-CRP	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Urine protein, albumin, creatinine	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
EKG, Neurometer, Chest PA, Abdominal sonography	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
Fundus photography, fat computed tomography	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks
HOMA-IR, HOMA-β	Measuring above all, investigators plan to investigate how clinical parameters help to predict and prevent diabetic vascular complications	an expected average of 12 weeks

Collaborators and Investigators

• Sponsor: Yonsei University

Study record dates

Study Major Dates

• Study Start: January 1, 2007
• Primary Completion (Anticipated): February 1, 2026
• Study Completion (Anticipated): February 1, 2026

Study Registration Dates

• First Submitted: March 27, 2016
• First Submitted That Met QC Criteria: March 27, 2016
• First Posted (Estimate): April 1, 2016

Study Record Updates

• Last Update Posted (Estimate): April 18, 2016
• Last Update Submitted That Met QC Criteria: April 15, 2016
• Last Verified: April 1, 2016

More Information

Terms related to this study

• Keywords: Diabetes; DM complication
• Additional Relevant MeSH Terms: Glucose Metabolism Disorders; Metabolic Diseases; Hyperglycemia; Glucose Intolerance
• Other Study ID Numbers: 3-2010-0195

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: YES
• IPD Plan Description: This study has a plan to share data