- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT02832089
Oral Carvedilol in Escalating Doses in the Acute Treatment of Atrial Fibrillation
July 11, 2016 updated by: Ravi Venkatachelam Chitrapu, Andhra Medical College
Oral carvedilol administered in escalating doses in patients with atrial fibrillation among patients with AF with fast ventricular rate.
Study Overview
Detailed Description
Patients with AF with FVR of any etiology were evaluated and given escalating doses of oral carvedilol in doses - 3.125mg OD, then 3.125 bid, then 6.25mg bid, then 12.5mg bid.
The ECG was recorded regularly and analysed for rate reduction or control.
Study Type
Interventional
Enrollment (Actual)
30
Phase
- Phase 3
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
18 years to 80 years (ADULT, OLDER_ADULT)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Description
Inclusion Criteria:
- AF with fast ventricular rate
Exclusion Criteria:
-
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Primary Purpose: TREATMENT
- Allocation: NA
- Interventional Model: SINGLE_GROUP
- Masking: NONE
Arms and Interventions
Participant Group / Arm |
Intervention / Treatment |
---|---|
EXPERIMENTAL: active arm
single arm study with one group given oral carvedilol.
|
oral carvedilol in escalating doses for reducing ventricular rate in AF patients
Other Names:
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
reduction in ventricular rate in AF patients
Time Frame: 24 hours
|
reduction in ventricular rate in patients with AF and fast ventricular rate.
|
24 hours
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start
December 1, 2000
Primary Completion (ACTUAL)
March 1, 2002
Study Completion (ACTUAL)
March 1, 2002
Study Registration Dates
First Submitted
December 28, 2015
First Submitted That Met QC Criteria
July 11, 2016
First Posted (ESTIMATE)
July 14, 2016
Study Record Updates
Last Update Posted (ESTIMATE)
July 14, 2016
Last Update Submitted That Met QC Criteria
July 11, 2016
Last Verified
July 1, 2016
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Pathologic Processes
- Heart Diseases
- Cardiovascular Diseases
- Arrhythmias, Cardiac
- Atrial Fibrillation
- Physiological Effects of Drugs
- Adrenergic beta-Antagonists
- Adrenergic Antagonists
- Adrenergic Agents
- Neurotransmitter Agents
- Molecular Mechanisms of Pharmacological Action
- Antihypertensive Agents
- Vasodilator Agents
- Protective Agents
- Membrane Transport Modulators
- Calcium-Regulating Hormones and Agents
- Calcium Channel Blockers
- Antioxidants
- Adrenergic alpha-1 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Carvedilol
Other Study ID Numbers
- 01AMCRVC
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
NO
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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