Effect of Rehabilitation Programs Based on Eccentric Exercise of Knee Extensor Muscles in Isotonic and Isokinetic Conditions After Anterior Cruciate Ligament Reconstruction

A randomized clinical trial involving 30 individuals submitted to ACL reconstruction will be conducted.

Participants will be randomized into: Group I, submitted to a muscular rehabilitation program based on eccentric isokinetic exercise; and Group II, submitted to a muscular rehabilitation program based on eccentric isotonic exercise. Concomitantly with the muscular rehabilitation protocols, individuals will undergo the same physiotherapeutic protocol with analgesia, edema reduction, range of motion, proprioception and functionality goals. Muscle rehabilitation programs based on eccentric isotonic and isokinetic exercise will begin 45 days after ACL reconstruction. The programs will last six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.

Study Overview

• Status: Completed
• Conditions: Anterior Cruciate Ligament Injury
• Intervention / Treatment: Other: Isokinetic eccentric exercises; Other: Isotonic eccentric exercises

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• Brazil
  • RS
    • Porto Alegre, RS, Brazil, 90050170
      • Universidade Federal de Ciências da Saúde de Porto Alegre

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 40 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Young adults aged between 18 and 40 years;
• Recreational athletes;
• Unilateral ACL injury;
• Presence of total or partial rupture of unilateral ACL within 90 days after injury;
• Male subjects;
• Classification of body mass index up to pre-obese (25.0 - 29.9 kg / m2);
• Not undergoing any strength training program for the lower limbs in the six months prior to the study.
• Acceptance of individuals in participating in the procedures proposed by the research.

Exclusion Criteria:

• Recidivism in ligament injuries;
• Associated ligament and / or meniscal lesions;
• Previous history (<6 months) of musculoskeletal lesions in the thigh;
• Patellar tendinopathy;
• Patellofemoral pain syndrome;
• Respiratory or cardiovascular conditions that limit the performance of exercises;
• Users of dietary supplements or anabolic steroids

Study Plan

How is the study designed?

Design Details

• Primary Purpose: Treatment
• Allocation: Randomized
• Interventional Model: Parallel Assignment
• Masking: Double

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
Experimental: Group 1.; The participants randomly allocated to this arm will undergo a muscular rehabilitation program based on the isokinetic eccentric exercise for the extensor muscles of the operated knee. The contralateral non-operated lower limb will be used as control, so it will not undergo any muscular rehabilitation program.	Other: Isokinetic eccentric exercises; The individuals of both groups will be submitted to the same physiotherapeutic protocol with objectives of analgesia, reduction of edema, recovery of range of motion, proprioception and functionality. 45 days after ACL reconstruction, subjects randomly allocated to this arm will be submitted to a muscle rehabilitation program based on isokinetic eccentric exercise lasting six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.
Active Comparator: Group 2.; The participants randomly allocated to this arm will undergo a muscular rehabilitation program based on the isotonic eccentric exercise for the extensor muscles of the operated knee. The contralateral non-operated lower limb will be used as control, so it will not undergo any muscular rehabilitation program.	Other: Isotonic eccentric exercises; The individuals of both groups will be submitted to the same physiotherapeutic protocol with objectives of analgesia, reduction of edema, recovery of range of motion, proprioception and functionality. 45 days after ACL reconstruction, subjects randomly allocated to this arm will be submitted to a muscle rehabilitation program based on isotonic eccentric exercise lasting six weeks, with training frequency of two sessions per week, separated by a minimum interval of 72 hours.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Time Frame
The femoral quadriceps muscle mass through nuclear magnetic resonance imaging	Change from baseline and six weeks after intervention protocol

Secondary Outcome Measures

Outcome Measure	Time Frame
Performance of knee extensors through computerized dynamometry	Change from baseline and six weeks after intervention protocol
Functionality of the individuals through Lysholm score	Change from baseline and six weeks after intervention protocol
Functionality of the individuals through single and triple hop test	Change from baseline and six weeks after intervention protocol

Collaborators and Investigators

• Sponsor: Federal University of Health Science of Porto Alegre
• Investigators: Principal Investigator: Marlon F Vidmar, MSc, Federal University of Health Science of Porto Alegre

Study record dates

Study Major Dates

• Study Start: July 1, 2016
• Primary Completion (Actual): December 1, 2017
• Study Completion (Actual): December 1, 2017

Study Registration Dates

• First Submitted: November 9, 2016
• First Submitted That Met QC Criteria: November 9, 2016
• First Posted (Estimate): November 11, 2016

Study Record Updates

• Last Update Posted (Actual): February 9, 2018
• Last Update Submitted That Met QC Criteria: February 7, 2018
• Last Verified: February 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Wounds and Injuries; Leg Injuries; Knee Injuries; Anterior Cruciate Ligament Injuries
• Other Study ID Numbers: FUHSPortoAlegre_III