Uterocervical Angle in the Termination of Second Trimester Pregnancy

The Predictive Performance of Uterocervical Angle in the Termination of Second Trimester Pregnancy

To evaluate the performance of uterocervical angle (UCA) in the prediction of second trimester terminations.

Study Overview

• Status: Completed
• Conditions: Abortion, Second Trimester
• Intervention / Treatment: Other: uterocervical angle

Detailed Description

Medical termination of pregnancy is a common procedure in obstetrics. In recent years, uterocervical angle (UCA) emerged as a new ultrasound parameter in the prediction of labor. Dziadosz et al concluded that the performance of UCA was even better than the cervical length in their cohort. A wide UCA during second trimester shown to have an increased risk of preterm labor and narrow angle was less likely to have labor.

The investigators are aimed to investigate predictive role of both cervical length and UCA in the termination of second trimester pregnancy.The investigators focused on nulliparous women who are taking misoprostol for the cervical preparation and aim to measure their UCA.

• Study Type: Observational
• Enrollment (Actual): 120

Contacts and Locations

Study Locations

• Turkey
  • Istanbul, Turkey, 34303
    • Kanuni SSTRH

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 40 years (Adult)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Female

• Sampling Method: Non-Probability Sample

Study Population

Pregnant population undergoing medical induced second trimester abortion.

Description

Inclusion Criteria:

• Nulliparous singleton pregnancy
• no previous systemic illnesses

Exclusion Criteria:

• abnormal Pap smear
• previous cesarean section
• history of dilatation and curettage (D&C)
• history of LEEP and cervical conization

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
Medical induced abortion; 120 singleton nulliparous patients are planning to complete the study period. Study group constitute of second trimester pregnancies between 14-24 weeks of gestation. All participants were nulliparous and had no systemic illnesses. The uterocervical angle will be measured in all participants before the induction of labor.	Other: uterocervical angle; uterocervical angle is the angle between lower segment of uterus and cervix

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
uterocervical angle	the angle between the lower segment of uterus and cervix	once at the beginning of enrollment

Collaborators and Investigators

• Sponsor: Kanuni Sultan Suleyman Training and Research Hospital

Publications and helpful links

Helpful Links

• Uterocervical angle: a novel ultrasound screening tool to predict spontaneous preterm birth.

Study record dates

Study Major Dates

• Study Start (Actual): October 15, 2016
• Primary Completion (Actual): August 30, 2017
• Study Completion (Actual): September 1, 2017

Study Registration Dates

• First Submitted: July 14, 2017
• First Submitted That Met QC Criteria: July 14, 2017
• First Posted (Actual): July 18, 2017

Study Record Updates

• Last Update Posted (Actual): September 6, 2017
• Last Update Submitted That Met QC Criteria: September 2, 2017
• Last Verified: September 1, 2017

More Information

Terms related to this study

• Keywords: uterocervical angle, second trimester abortion
• Other Study ID Numbers: 2016/5

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No