Cerebral Oximetry and Anesthetic Technique

Evaluation of the Effects of Spinal Versus General Anesthesia on Transcranial Cerebral Oxygen Saturation in Geriatric Patients Undergoing Total Hip Arthroplasty

Sponsors

Lead Sponsor: Antalya Training and Research Hospital

Source Antalya Training and Research Hospital
Brief Summary

The purpose of the study is to compare the effects of spinal and general anesthesia on transcranial regional cerebral oxygen saturation in geriatric patients undergoing total hip arthroplasty.

Detailed Description

Geriatric patients who received anesthesia undergoing total hip arthroplasty were randomized by means of a computer-generated randomization order into two groups; general anesthesia group (Group 1) and spinal anesthesia group (Group 2). Before and after induction of the general or spinal anesthesia, patients were monitorized with near infrared spectroscopy for regional cerebral oxygen saturation. Findings were compared statistically.

Overall Status Completed
Start Date January 2017
Completion Date August 2017
Primary Completion Date June 2017
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Change in transcranial regional cerebral oxygenation (rSO2) 60 minutes
Secondary Outcome
Measure Time Frame
Post anesthetic complications 1 day
Enrollment 82
Condition
Intervention

Intervention Type: Other

Intervention Name: general anesthesia

Description: effect of general anesthesia on transcranial regional cerebral oxygen saturation

Arm Group Label: general anesthesia

Intervention Type: Other

Intervention Name: spinal anesthesia

Description: effect of spinal anesthesia on transcranial regional cerebral oxygen saturation

Arm Group Label: spinal anesthesia

Eligibility

Criteria:

Inclusion Criteria:

- patients who undergo elective total hip arthroplasty

- American Society of Anesthesiologists class 1 to 3

- Ability to consent

Exclusion Criteria:

- Pulmonary disease

- History of allergic reaction to local anaesthetics

- Peripheral neuropathy

- Neurologic disease

- Coagulation disorders

Gender: All

Minimum Age: 65 Years

Maximum Age: 90 Years

Healthy Volunteers: No

Overall Official
Verification Date

November 2017

Responsible Party

Type: Sponsor

Keywords
Has Expanded Access No
Number Of Arms 2
Arm Group

Label: general anesthesia

Type: Active Comparator

Description: Patients in this group were randomized to receive general anesthesia.

Label: spinal anesthesia

Type: Active Comparator

Description: Patients in this group were randomized to receive spinal anesthesia.

Study Design Info

Allocation: Randomized

Intervention Model: Parallel Assignment

Primary Purpose: Prevention

Masking: Triple (Participant, Care Provider, Outcomes Assessor)

Source: ClinicalTrials.gov