Social Behavior in Depression (HLGDep)

In the project, investigators basically plan to test the difference in social behavior and social cognition between depressive patients and healthy individuals. To test this, investigators plan to use traditional or novel behavioral experiment paradigms to target various behaviors.

Study Overview

• Status: Unknown
• Conditions: Depression

• Study Type: Observational
• Enrollment (Anticipated): 25

Contacts and Locations

• Study Contact: Name: Yina Ma, Doctor; Phone Number: +8613810258647; Email: yma@bnu.edu.cn

Study Locations

• China
  • Beijing, China
    • Recruiting
    • HuiLongGuan Hospital
    • Contact: Yina Ma, Doctor
    • Principal Investigator: Yina Ma, Doctor

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 60 years (Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

Individuals diagnosed with depression and healthy control

Description

Inclusion Criteria:

• Age range between 18 and 60
• Education experience above high school
• Score for Hamilton's Depression Scale >=17
• Diagnosis of depression through Scid

Exclusion Criteria:

• Undergoing electric shock treatment in 3 months
• Excluding those who with bipolar disorder
• Excluding those who with postpartum depression
• Excluding those who with hysteria

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Control
• Time Perspectives: Cross-Sectional

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Prosocial behavior	The prosocial behavior will be assessed by conventional economic games, including dictator game, message game, and ultimatum game.	Baseline
Cognitive flexibility	Cognitive flexibility will be assessed by psychological cognitive paradigm, i.e. reversal learning paradigm. The participants will be asked to choose the item with high probability to win reward.	Baseline
Valuation of social information	The valuation of social information was measured by psychological paradigm, developed from animal studies, called "pay-per-view". The participants will be asked make decision about more social information or more monetary reward.	Baseline
Optimism bias	Participants will complete two sessions of life event estimation, i.e. estimating their likelihood of experiencing each event on a self-paced basis.	Baseline
Emotion recognition	After viewing a video, participants will be asked to judge the person's attitude in the video. Through this paradigm, investigators could test emotional bias in social interaction in depressive patients.	Baseline
Model-free & model-based tendency	Participants will be asked to complete a two-stage task, by choosing the stimuli with high probability to obtain reward.	Baseline

Collaborators and Investigators

• Sponsor: Beijing Normal University
• Collaborators: Huilongguan Hospital
• Investigators: Study Chair: Yina Ma, Doctor, Beijing Normal University

Study record dates

Study Major Dates

• Study Start (Actual): February 1, 2017
• Primary Completion (Anticipated): February 16, 2018
• Study Completion (Anticipated): March 1, 2018

Study Registration Dates

• First Submitted: January 22, 2018
• First Submitted That Met QC Criteria: January 26, 2018
• First Posted (Actual): January 30, 2018

Study Record Updates

• Last Update Posted (Actual): February 6, 2018
• Last Update Submitted That Met QC Criteria: February 4, 2018
• Last Verified: February 1, 2018

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Behavioral Symptoms; Mental Disorders; Mood Disorders; Depression; Depressive Disorder
• Other Study ID Numbers: HLGdepression

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No