Impact of Dried Moringa Oleifera Leaves as Value Added Supplement in Enhancing Hemoglobin Status of Reproductive Aged Females of Low Socio-economic Group

Impact of Dried Moringa Oleifera Leaves in Enhancing Hemoglobin Status

Sponsors

Lead sponsor: Kinnaird College for Women

Source Kinnaird College for Women
Brief Summary

This research project is aimed at combating the nutritional deficiencies (Iron deficiency anemia) of reproductive aged females belonging to the underprivileged group of the society. Since anemia is one of the causes of still child-birth, preterm and low birth weight babies causing cognitive disabilities during the later years of life, So, it needs to be treated on priority bases.

Detailed Description

Mal-nutrition is a significant problem in the developing world, with serious consequences for human health and socio-economic development. It is estimated that over 43% women of reproductive age suffer from anemia. In Pakistan, about 35% non-pregnant and 51% pregnant women are suffering from anemia. Prevention and control against anemia rely on iron supplementation and food fortification on large scale. Both these methods are not affordable and feasible for poor people. Previous studies have shown that about 97% females do not meet their iron requirements. The possible reason to this can be iron losses from body including menstruation. To overcome these problems, culturally accepted, inexpensive and modified recipes were used to supply iron with addition of Moringa oleifera leaves (rich and cheap source of iron). In the study 34 of ages between 13-30 years were selected (excluding pregnant and lactating women) and were intervened with value added supplement " Moringa oleifera" for a period of three months. These recipes were made part of the diet by giving a dose of three meals per day on regular basis. Each recipe contained about 15 g of Dried Moringa powder. After the intervention, out of total 34, 3 females achieved normal Hb level of 12 g/dl. Overall, 94% cases of the study showed improvement of 1.8 g/dl (on average) in Hb level after intervention. There was a significant increase in blood Hb level (p<0.000) and both the var5iables were strongly and positively correlated (0.928). Variables of age and levels of education were weakly but significantly related to each other (p<0.001) in improving Hb after intervention.

Females with higher levels of education showed better response towards intervention.

After intervention with Moringa oleifera, an average increase of 1.5 g/dl in Hb was observed in the entire population whereas, members of Group B (ages above 18) showed more increase of 14.96% in their Hb level as compared to members of Group A (ages below 18) showing an increase of 12.96% in Hb level.

Overall Status Completed
Start Date January 2013
Completion Date April 2014
Primary Completion Date December 2013
Phase N/A
Study Type Interventional
Primary Outcome
Measure Time Frame
Improvement in Hemoglobin status 3 months
Secondary Outcome
Measure Time Frame
Changes in BMI 5 months
Enrollment 34
Condition
Intervention

Intervention type: Dietary Supplement

Intervention name: Dried Moringa oleifera leaves

Eligibility

Criteria:

Inclusion Criteria:

- Reproductive aged females (13-30 years)

Exclusion Criteria:

- pregnant and Lactating women

Gender: Female

Gender based: Yes

Gender description: Reproductive aged females ( those who are capable of bearing a child)

Minimum age: 13 Years

Maximum age: 30 Years

Healthy volunteers: No

Overall Official
Last Name Role Affiliation
Madeeha Munir, M.Phil Principal Investigator Kinnaird College for Women
Verification Date

May 2018

Responsible Party

Responsible party type: Principal Investigator

Investigator affiliation: Kinnaird College for Women

Investigator full name: Madeeha Munir

Investigator title: Former Lecturer Minhaj University

Keywords
Has Expanded Access No
Condition Browse
Number Of Arms 2
Arm Group

Arm group label: Group A (Below 18 years)

Arm group type: Active Comparator

Description: Dried Moringa oleifera leaves (15g/recipe)

Arm group label: Group B (Above 18)

Arm group type: Active Comparator

Description: Dried Moringa oleifera leaves (15g/recipe)

Patient Data No
Study Design Info

Allocation: Non-Randomized

Intervention model: Single Group Assignment

Intervention model description: In the study 34 of ages between 13-30 years divided into 2 age groups (below and above 18) were selected (excluding pregnant and lactating women) and were intervened with value added supplement " Moringa oleifera" for a period of three months.

Primary purpose: Supportive Care

Masking: None (Open Label)

Source: ClinicalTrials.gov