Acute Pancreatitis: Study of Possible Etiologies and Risk Factors Affecting Outcome

Acute Pancreatitis: Study of Possible Etiologies and Risk Factors Affecting Outcome (Hospital Based Study)

This study is to assess the frequency of different etiologies of acute pancreatitis in our locality & assess the effect of different risk factors on outcome of the patients.

Study Overview

• Status: Completed
• Conditions: Pancreatitis

• Study Type: Observational
• Enrollment (Actual): 300

Contacts and Locations

Study Locations

• Egypt
  • Assiut, Egypt, 71515
    • Ahmed Mohammed Abu-Elfatth

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Probability Sample

Study Population

All patients admitted in assuit university hospital during the period of the study and diagnosed as acute pancreatitis

Description

Inclusion Criteria:

-

Diagnosis of acute pancreatitis according to the following: the presence of two of the three following criteria:

• abdominal pain consistent with the disease
• serum amylase and or lipase greater than three times the upper limit of normal
• characteristic findings from abdominal imaging Contrast-enhanced computed tomographic (CECT) and or magnetic resonance imaging (MRI) of the pancreas

Exclusion Criteria:

• No exclusion criteria .

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
The frequency of different etiologies of AP in our locality	At the end of study, total number of patients of each etiology of acute pancreatitis will be calculated as (Gallstones, Alcohol, triglyceridemia, Idiopathic, ERCP,..)	1 year

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Outcome of the patients according to the Atlanta Classification 2012 revision	Effect of each risk factor on outcome as progression to mild, moderate severe and severe pancreatitis "according to the Atlanta Classification 2012 revision",	1 year
Hospital duration of stay	Effect of each risk factor on hospital duration of stay	1 year
Rate of transfer to ICU	Effect of each risk factor on rate of transfer to ICU	1 year
Mortality	Effect of each risk factor on mortality	1 year

Collaborators and Investigators

• Sponsor: Assiut University
• Investigators: Study Director: Ashraf Osman, MD, Assiut University

Study record dates

Study Major Dates

• Study Start (Actual): October 1, 2018
• Primary Completion (Actual): October 1, 2022
• Study Completion (Actual): October 30, 2022

Study Registration Dates

• First Submitted: May 21, 2018
• First Submitted That Met QC Criteria: July 24, 2018
• First Posted (Actual): July 26, 2018

Study Record Updates

• Last Update Posted (Actual): August 9, 2023
• Last Update Submitted That Met QC Criteria: August 7, 2023
• Last Verified: August 1, 2023

More Information

Terms related to this study

• Keywords: pancreatitis
• Additional Relevant MeSH Terms: Digestive System Diseases; Pancreatic Diseases; Pancreatitis
• Other Study ID Numbers: Acute pancreatitis

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No