The Relation Between Constitutional Types and Indices of Tongue, Pulse,and Ausculative Diagnosis

This study aims to evaluate indices of tongue diagnosis, ausculative diagnosis, and pulse diagnosis in the determination of institutions.

Study Overview

• Status: Completed
• Conditions: Non-disease State
• Intervention / Treatment: Diagnostic test: Pulse, tongue image, and voice sound

Detailed Description

Constitution differentiation is important for the prescription of Chinese medicines. In previous studies, researchers usually used constitutional questionnaires to determine constitutions.However, the importance of tongue diagnosis and pulse diagnosis remained unclear. The specific aim of this study is to evaluation indices of tongue diagnosis, auscultative diagnosis, and pulse diagnosis in the determination of constitutions. Meeting of specialists will determine the characteristics for each constitution first. This study plans to recruit 200 volunteers and determine their constitutions by constitutional questionnaires. Tongue manifestations and pulse pressure waveforms will be taken at the same time by standardized instruments. Relations between the indices and each constitution will be determined by multiple linear regression and logistic regression analysis. Then the percentage of importance of a specific index in a specific constitutional type could be determine.

• Study Type: Observational
• Enrollment (Actual): 281

Contacts and Locations

Study Locations

• Taiwan
  • Taichung, Taiwan, 404
    • CMUH

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 20 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No
• Genders Eligible for Study: All

• Sampling Method: Probability Sample

Study Population

aged older than 20 years old

Description

Inclusion Criteria:

• Volunteers without aged older than 20 years old

Exclusion Criteria:

• Pregnant
• taking any medicine currently
• suffering for acute disease currently

Study Plan

How is the study designed?

Design Details

• Observational Models: Case-Only
• Time Perspectives: Cross-Sectional

Number of groups / cohorts

9

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
normal; A normal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Qi deficiency; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Damp heat; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Yang deficiency; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Yin deficiency; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Phlagm; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Blood stasis; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Qi stagnation; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM
Special; One of an abnormal constitution condition in TCM.	Diagnostic test: Pulse, tongue image, and voice sound; They are four diagnosis methods of TCM

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Tongue image	A photograph of tongue will be taken and the RGB color values of the tongue will be analyzed using Photoshop software	The photograph will be taken only at the first day the subject has been recruited

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Acoustic sound	Voice wave analysis of an one-second /a/ sound (in only one time point)	The voice waves will be taken only once at the first day the subject has been recruited
Pulse image	Time-domained pulse waveform of the radial artery will be recorded for about 1 minute	The pulse waveforms will be recorded at the first day the subject has been recruited

Collaborators and Investigators

• Sponsor: China Medical University Hospital
• Collaborators: Committee on Chinese Medicine and Pharmacy

Study record dates

Study Major Dates

• Study Start (Actual): December 15, 2010
• Primary Completion (Actual): December 14, 2011
• Study Completion (Actual): December 14, 2011

Study Registration Dates

• First Submitted: July 9, 2018
• First Submitted That Met QC Criteria: August 28, 2018
• First Posted (Actual): August 31, 2018

Study Record Updates

• Last Update Posted (Actual): August 31, 2018
• Last Update Submitted That Met QC Criteria: August 28, 2018
• Last Verified: August 1, 2018

More Information

Terms related to this study

• Other Study ID Numbers: DMR99-IRB-271