Perception of Smell and Taste During Antibiotic Treatment (OGUSTA)

Antibiotic use may be associated with effects on the perception of smell and taste. These effects are poorly known. The mechanisms can be very diverse, and the effect can be very variable depending on the type of antibiotic used, the dose, and the duration.

The aim of this study is to analyze the perception of the taste and olfactory capacities of patients, during an antibiotic treatment.

Study Overview

• Status: Completed
• Conditions: Infectious Disease
• Intervention / Treatment: Behavioral: Smell and Taste and questionnaire

• Study Type: Observational
• Enrollment (Actual): 3

Contacts and Locations

Study Locations

• France
  • Lyon, France, 69004
    • Department of Infectious and Tropical Diseases of the Croix Rousse Hospital of the Civil Hospitals of Lyon

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years and older (Adult, Older Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Patient meeting the eligibility criteria followed in the department of Infectious and Tropical Diseases of the Croix Rousse Hospital of the Civil Hospitals of Lyon

Description

Inclusion Criteria:

• Major patient
• Patient with bacterial infectious disease requiring antibiotic treatment.
• Having been informed about the study and not having opposed to participate

Exclusion Criteria:

• Patient under legal protection
• Patient refusing to participate

Study Plan

How is the study designed?

Design Details

• Observational Models: Cohort
• Time Perspectives: Prospective

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Questionnaire on Perception of taste	Collection of scores on perception of taste, during questionnaires to be completed before, during, and after taking antibiotics. Qualitative analysis.	Time of antibiotic treatment (maximum 6 months)
Questionnaire on Perception of smell	Collection of scores on perception of smell, during questionnaires to be completed before, during, and after taking antibiotics. Qualitative analysis.	Time of antibiotic treatment (maximum 6 months)

Collaborators and Investigators

• Sponsor: Hospices Civils de Lyon

Study record dates

Study Major Dates

• Study Start (Actual): October 4, 2019
• Primary Completion (Actual): May 28, 2020
• Study Completion (Actual): May 28, 2020

Study Registration Dates

• First Submitted: March 26, 2019
• First Submitted That Met QC Criteria: March 26, 2019
• First Posted (Actual): March 28, 2019

Study Record Updates

• Last Update Posted (Estimated): October 9, 2023
• Last Update Submitted That Met QC Criteria: October 6, 2023
• Last Verified: October 1, 2023

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Pathologic Processes; Disease Attributes; Infections; Communicable Diseases
• Other Study ID Numbers: 69HCL19_0117

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No