- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT04507230
COVID-19 Associated Coagulopathy in Egypt
March 10, 2021 updated by: Azza Abdelaal, Assiut University
Assessment of COVID-19 Associated Coagulopathy and Hypercoagulable State in Upper Egypt
Coagulopathy is one of the most significant prognostic factors in patients with COVID-19 and is associated with increased mortality and admission to critical care.
Most commonly observed coagulopathy in patients hospitalized with COVID-19 (COVID-19-associated coagulopathy) is characterized by increased D-dimer and fibrinogen levels.
71% of patients who did not survive hospitalization reported to have developed disseminated intravascular coagulation (DIC) compared to 0.6% of survivors.
Study Overview
Status
Completed
Conditions
Detailed Description
studying the detailed coagulation screen and second line coagulation parameters including both thrombophilia screen and other acute phase coagulation factors.
Study Type
Observational
Enrollment (Actual)
106
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
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-
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Assiut, Egypt, 71515
- Assiut university hospitals
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Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
- Child
- Adult
- Older Adult
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Probability Sample
Study Population
COVID 19 positive by RT- PCR who are admitted to Assiut University hospitals, Egypt.
Age and sex matched controls
Description
Inclusion Criteria:
- patients with COVID 19 positive by RT- PCR
Exclusion Criteria:
- no exclusions
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Coagulation screen
Time Frame: 1 month
|
Full coagulation screen
|
1 month
|
Thrombophilia screen
Time Frame: 1 month
|
Full thrombophilia screen
|
1 month
|
VWF, FVIII
Time Frame: 1 month
|
VWFAg, FVIII
|
1 month
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Sponsor
Publications and helpful links
The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.
Helpful Links
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
August 7, 2020
Primary Completion (Actual)
October 31, 2020
Study Completion (Actual)
October 31, 2020
Study Registration Dates
First Submitted
August 7, 2020
First Submitted That Met QC Criteria
August 7, 2020
First Posted (Actual)
August 11, 2020
Study Record Updates
Last Update Posted (Actual)
March 11, 2021
Last Update Submitted That Met QC Criteria
March 10, 2021
Last Verified
March 1, 2021
More Information
Terms related to this study
Keywords
Additional Relevant MeSH Terms
- Cardiovascular Diseases
- Vascular Diseases
- Coronavirus Infections
- Coronaviridae Infections
- Nidovirales Infections
- RNA Virus Infections
- Virus Diseases
- Infections
- Respiratory Tract Infections
- Respiratory Tract Diseases
- Pneumonia, Viral
- Pneumonia
- Lung Diseases
- Hematologic Diseases
- Hemorrhagic Disorders
- COVID-19
- Hemostatic Disorders
- Blood Coagulation Disorders
Other Study ID Numbers
- 17300413
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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