Evaluation Study: Obsessive-compulsive Disorders in Childhood and Young Adulthood

Obsessive-compulsive disorders are very damaging illnesses that can already manifest in childhood and adolescence. With an average prevalence from 1 - 3%, they are one of the most frequently diagnosed psychiatric illness in these age groups. With the further use of data, the treatment success can be significantly improved; causal variables/predictors can be recognized, understood and taken carefully into account. The anticipated incremental knowledge will ultimately help children and young people with obsessive-compulsive disorders to receive faster and more effective treatment.

Study Overview

• Status: Recruiting
• Conditions: Obsessive-compulsive Disorder

• Study Type: Observational
• Enrollment (Estimated): 625

Contacts and Locations

• Study Contact: Name: Juliane Ball, Dr. rer. Nat. Dipl. Psych; Phone Number: +41 43 499 26 26; Email: juliane.ball@puk.zh.ch
• Study Contact Backup: Name: Susanne Walitza, Prof. Dr. med. Dipl.-Psych.; Phone Number: +41 (0)43 499 26 26; Email: susanne.walitza@puk.zh.ch

Study Locations

• Switzerland
  • ZH
    • Zurich, ZH, Switzerland, 8032
      • Recruiting
      • Psychiatric University Clinics, Department of Child and Adolescent Psychiatry
      • Contact: Siebke Melfsen, Dr.; Phone Number: +49 45 42 98 69 77 4; Email: siebke.melfsen@online.de
      • Contact: Susanne Walitza, Prof. Dr. med. Dipl.-Psych.; Phone Number: +41 43 499 26 26; Email: susanne.walitza@puk.zh.ch

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 4 years to 18 years (Child, Adult)
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

The sample consist of pupils with obsessive-compulsive disorder 4 to 18 years

Description

Inclusion Criteria:

• Children and young people from 8-18 years of age who fulfill the international classification of diseases tenth edition (ICD-10) , obsessive-compulsive disorder handled in our clinic.
• Good German language speaking skills
• IQ > 75
• All study participants or their legal representative have given written permission for their experiences to be documented in the study.

Exclusion Criteria:

• Schizophrenia-related disorders (psychoses)
• Missing data
• Data sets without confirmed diagnosis
• Purely consultaive patient interview (no therapy intervention prescribed)

Study Plan

How is the study designed?

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Symptoms severity of obsessive and compulsive symptoms in children and adolescents	The clinician report questionnaire (BY-BOCS) contains 19 items designed to assess severity of obsessive and compulsive symptoms in children and adolescents.The test uses a four point scale to rate the severity of their obsessive compulsive behaviors. Higher score means a worse outcome.	24 months

Collaborators and Investigators

• Sponsor: Susanne Walitza
• Investigators: Principal Investigator: Susanne Walitza, Prof. Dr. med. Dipl.-Psych., Sponsor-Investigator

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2020
• Primary Completion (Estimated): March 1, 2026
• Study Completion (Estimated): March 1, 2026

Study Registration Dates

• First Submitted: January 21, 2021
• First Submitted That Met QC Criteria: January 21, 2021
• First Posted (Actual): January 25, 2021

Study Record Updates

• Last Update Posted (Actual): May 13, 2025
• Last Update Submitted That Met QC Criteria: May 12, 2025
• Last Verified: May 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Personality Disorders; Anxiety Disorders; Compulsive Personality Disorder; Obsessive-Compulsive Disorder
• Other Study ID Numbers: KJPP 2019-00230

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: UNDECIDED

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No