- ICH GCP
- US Clinical Trials Registry
- Clinical Trial NCT05578105
Prevalence and Genetic Alternation of Autoimmune Polyglandular Syndrome Type II in Taiwan
October 10, 2022 updated by: National Taiwan University Hospital
Autoimmune polyendocrine syndrome (APS) is an autoimmune disease involving at least two endocrine organ.
It is classified into type I and type II diseases.
Among them, APS type II is more common.
It is diagnosed when two of the three following diseases are diagnosed in the same patient, including type 1 diabetes mellitus, autoimmune thyroid disease, and primary adrenal insufficiency.
In this study, we will observe the epidemiology, clinical characteristics, and genetic variants of APS II in Taiwan.
Study Overview
Status
Recruiting
Conditions
Intervention / Treatment
Study Type
Observational
Enrollment (Anticipated)
650
Contacts and Locations
This section provides the contact details for those conducting the study, and information on where this study is being conducted.
Study Locations
-
-
-
Taipei, Taiwan, 100
- Recruiting
- National Taiwan University Hospital
-
Contact:
- Shyang-Rong Shih, MD. PhD
- Phone Number: +886-972653337
- Email: srshih@ntu.edu.tw
-
-
Participation Criteria
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
Eligibility Criteria
Ages Eligible for Study
20 years and older (Adult, Older Adult)
Accepts Healthy Volunteers
No
Genders Eligible for Study
All
Sampling Method
Non-Probability Sample
Study Population
We study patients with autoimmune polyendocrine syndrome type II
Description
Inclusion Criteria:
- Patients visited NTUH during 2006-2021, and had at least two of the three diseases: type 1 DM, primary adrenal insufficiency, and autoimmune thyroid disease.
Exclusion Criteria:
- Patients aged less than 20 years old
Study Plan
This section provides details of the study plan, including how the study is designed and what the study is measuring.
How is the study designed?
Design Details
- Observational Models: Case-Only
- Time Perspectives: Retrospective
Cohorts and Interventions
Group / Cohort |
Intervention / Treatment |
---|---|
Autoimmune polyendocrine syndrome type II
patients with autoimmune polyendocrine syndrome type II
|
No intervention, only observation
|
What is the study measuring?
Primary Outcome Measures
Outcome Measure |
Measure Description |
Time Frame |
---|---|---|
Rates of endocrine organs involved
Time Frame: 2022/1/1 ~ 2026/12/31
|
We will observe the rate of each endocrine organ involved, including adrenal gland, thyroid, and pancreas
|
2022/1/1 ~ 2026/12/31
|
Collaborators and Investigators
This is where you will find people and organizations involved with this study.
Study record dates
These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.
Study Major Dates
Study Start (Actual)
January 1, 2022
Primary Completion (Anticipated)
December 31, 2026
Study Completion (Anticipated)
December 31, 2026
Study Registration Dates
First Submitted
October 10, 2022
First Submitted That Met QC Criteria
October 10, 2022
First Posted (Actual)
October 13, 2022
Study Record Updates
Last Update Posted (Actual)
October 13, 2022
Last Update Submitted That Met QC Criteria
October 10, 2022
Last Verified
October 1, 2022
More Information
Terms related to this study
Additional Relevant MeSH Terms
Other Study ID Numbers
- 202112250RINC
Plan for Individual participant data (IPD)
Plan to Share Individual Participant Data (IPD)?
No
Drug and device information, study documents
Studies a U.S. FDA-regulated drug product
No
Studies a U.S. FDA-regulated device product
No
This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.
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