Evaluation of the Vulnerable Carotid Atherosclerotic Plaque: A Clinical Multicenter Study

April 28, 2023 updated by: huang pintong
Evaluation of carotid plaque vulnerability based on ultrasound imaging features， proteomics and metabolomics: a clinical multicenter study

Study Overview

Status

Recruiting

Conditions

Detailed Description

Carotid artery plaque tissue specimen for proteomics. Blood were collect for metabolomics.

Study Type

Observational

Enrollment (Anticipated)

57

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • China
    • Zhejiang
      • Hangzhou, Zhejiang, China, 310000
        • Recruiting
        • Department of Ultrasound, Second Affiliated Hospital, School of Medicine, Zhejiang University
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Child
  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Probability Sample

Study Population

Patients undergoing carotid endarterectomy

Description

Inclusion Criteria:

  1. Patients who meet the CEA surgical indications;
  2. Age>18 years old;
  3. Patients who sign informed consent forms

Exclusion Criteria:

  1. Those with severe calcification of plaques and obvious acoustic shadows, and poor image quality;
  2. Contraindications to ultrasound contrast, such as those who are allergic to contrast agents;
  3. Intracardiac right to left shunt;

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Stable Carotid Atherosclerotic Plaques
Unstable Carotid Atherosclerotic Plaques

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
ultrasound
Time Frame: 2023.05
B mode
2023.05

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

huang pintong

Collaborators

Second Affiliated Hospital, School of Medicine, Zhejiang University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

April 18, 2023

Primary Completion (Actual)

April 20, 2023

Study Completion (Anticipated)

April 18, 2024

Study Registration Dates

First Submitted

April 28, 2023

First Submitted That Met QC Criteria

April 28, 2023

First Posted (Actual)

May 9, 2023

Study Record Updates

Last Update Posted (Actual)

May 9, 2023

Last Update Submitted That Met QC Criteria

April 28, 2023

Last Verified

April 1, 2023

More Information

Terms related to this study

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 2023-0402

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

UNDECIDED

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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