A Cross-sectional Survey of Colorectal Cancer Patients in Different Age Groups

A Cross-sectional Survey of Symptomatic Characteristics, Family History and Pathologic Features of Colorectal Cancer Patients in Different Age Groups

This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

Study Overview

• Status: Recruiting
• Conditions: Colorectal Cancer; Age Problem
• Intervention / Treatment: Other

Detailed Description

Colorectal cancer is one of the common and highly prevalent malignant tumors of the gastrointestinal system. Previous studies have found that there may be some differences in disease characteristics and prognosis of colorectal cancer patients at different ages, such as patients with early-onset colorectal cancer (age <50 years) tend to have a worse prognosis than patients with late-onset colorectal cancer (age ≥50 years). However, existing studies on the characteristics of colorectal cancer patients at different ages are not well studied to answer the differences between these patients and develop targeted diagnostic and treatment strategies. Cross-sectional survey research, which uses survey research to collect data on a characteristic group over a certain period of time and statistically analyzes the data to obtain the characteristics of a certain disease or a certain treatment strategy, is a more mature approach that is particularly suitable for the questions that need to be answered in this study. Investigators found that no similar studies have been registered and conducted by searching the official websites of the China Clinical Research Registry and Clinical Trial, and there is a lack of research data on the Chinese population. Therefore, investigators believe there is an urgent need for a cross-sectional survey to study the symptomatic characteristics, family history, and pathologic features of colorectal cancer patients. This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

• Study Type: Observational
• Enrollment (Estimated): 430

Contacts and Locations

• Study Contact: Name: Yuliuming Wang, Dr.; Phone Number: +86-15765191796; Email: wylm3141@163.com

Study Locations

• China
  • Heilongjiang
    • Harbin, Heilongjiang, China, 150086
      • Recruiting
      • The 2nd Affiliated Hospital of Harbin Medical University
      • Contact: Guiyu Wang; Email: guiywang@163.com

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult; Older Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

Colorectal cancer patients in different age groups

Description

Inclusion Criteria:

1. Adults aged 18 years and older with a pathologic diagnosis of colorectal cancer;
2. Undergoing surgical treatment of the primary lesion;
3. Voluntary participation of patients.

Exclusion Criteria:

1. Do not agree to participate in the survey or withdraw informed consent
2. Patients did not receive surgical treatment or did not undergo pathologic examination

Study Plan

How is the study designed?

Number of groups / cohorts

4

Cohorts and Interventions

Group / Cohort
Under 60 group; Colorectal cancer paitents aged under 60 years old ( do not include 60 years old)
60-69 group; Colorectal cancer paitents aged 60-69 years old
70-79 group; Colorectal cancer paitents aged 70-79 years old
80 and over group; Colorectal cancer paitents aged 80 and over 80 years old

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Characteristics of clinical symptoms	Comparison of the characteristics of clinical symptoms in patients of different ages;	2023.12-2024.10
Family history	Comparison of the probability of having a family history in patients of different age stages;	2023.12-2024.10
Pathological characteristics	Comparison of pathological characteristics of patients at different age stages;	2023.12-2024.10

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Risk factors	Analysis of risk factors for stage progression in colorectal cancer patients	2024.09-2024.10

Collaborators and Investigators

• Sponsor: Wang Guiyu
• Investigators: Study Chair: Ye Tian, Prof., Second Affiliated Hospital of Harbin Medical University Ethics Committee

Study record dates

Study Major Dates

• Study Start (Actual): December 12, 2023
• Primary Completion (Estimated): October 1, 2024
• Study Completion (Estimated): December 1, 2024

Study Registration Dates

• First Submitted: October 9, 2023
• First Submitted That Met QC Criteria: November 21, 2023
• First Posted (Actual): November 24, 2023

Study Record Updates

• Last Update Posted (Actual): January 5, 2024
• Last Update Submitted That Met QC Criteria: January 4, 2024
• Last Verified: January 1, 2024

More Information

Terms related to this study

• Keywords: Family history; Colorectal caner; Age group; Symptomatic characteristics; Pathologic features
• Additional Relevant MeSH Terms: Digestive System Diseases; Neoplasms; Neoplasms by Site; Gastrointestinal Neoplasms; Digestive System Neoplasms; Gastrointestinal Diseases; Colonic Diseases; Intestinal Diseases; Intestinal Neoplasms; Rectal Diseases; Colorectal Neoplasms
• Other Study ID Numbers: 2ndHarbinMUSUV

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No