Evaluation of the French Version of the PEERS Social Skills Training Program for Adolescents With Rare Neurodevelopmental Disorders (PEERS-MRND)

Evaluation of the French Version of the PEERS Social Skills Training Program for Adolescents With Rare Neurodevelopmental Disorders / PEERS-MRND

Adolescents and young adults with rare neurodevelopmental disorders are at risk of developing psychiatric pathologies during the transition to adulthood. Loneliness and lack of social relationships can lead to anxiety and depression in adolescents and young adults with rare neurodevelopmental disorders. Anxiety and depression are major risk factors for the transition to psychiatric symptoms in adulthood. The improvement of social skills and the positive evolution of social relationships in adolescents and young adults with rare neurodevelopmental disorders can lead to a reduction in the risk factors for anxiety and depression. It therefore seems essential to evaluate the evolution of social skills in this population of young adults under the care of the social skills program, PEERS, in France to assess the overall benefit of the program, particularly in this population of young people with rare neurodevelopmental disorders.

Study Overview

• Status: Completed
• Conditions: Neurodevelopmental Disorders; Rare Diseases

• Study Type: Observational
• Enrollment (Actual): 64

Contacts and Locations

Study Locations

• France
  • Île-de-France Region
    • Paris, Île-de-France Region, France, 75015
      • Necker - Enfants Malades Hospital

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Child; Adult
• Accepts Healthy Volunteers: No

• Sampling Method: Non-Probability Sample

Study Population

The study will focus on data from 40 patients with rare neurodevelopmental disorders and their 40 relatives/friends.

Description

Inclusion criteria:

• Aged between 12 and 30 years, included at the start of the social skills program.
• Patients with rare neurodevelopmental diseases
• Patients benefiting from the social skills program
• Appropriate level of verbal elaboration
• Patient with a family member or a friend also participating in the social skills program

Non-inclusion criteria :

• Opposition of the patient or, if a minor, of his/her parents to participation in the study
• Patient not psychiatrically stabilized: acute symptoms of anxiety, depression, psychotic disorders.
• Severe intellectual disability

Study Plan

How is the study designed?

Number of groups / cohorts

2

Cohorts and Interventions

Group / Cohort
Patient; Inclusion criteria: Aged between 12 and 30 years, included at the start of the social skills program.; Patients with rare neurodevelopmental diseases; Patients benefiting from the social skills program; Appropriate level of verbal elaboration; Patient with a family member or a friend also participating in the social skills program Non-inclusion criteria : Opposition of the patient or, if a minor, of his/her parents to participation in the study; Patient not psychiatrically stabilized: acute symptoms of anxiety, depression, psychotic disorders.; Severe intellectual disability
Family member or friend; Inclusion criteria: be over 18 years; be a close relative or friend of a patient and share in his or her daily life; have taken or are taking the social skills program Non-inclusion criteria : - Opposition to participation in the study

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases participating in the social skills program	Quality of Play Questionnaire-Adolescent (QPQ-A) (QSQP in French)	2023 - 2025
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases	Friendship Quality Scale (FQS)	2023 - 2025
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases	Social Anxiety Scale for Adolescent (SAS-A)	2023 - 2025
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases	Loneliness and Social Dissatisfaction Scale (L&SD)	2023 - 2025
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases	Test of Adolescent Social Skills Knowledge (TASSK)	2023 - 2025
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases	Self-Assessment of Conversational Skills (AHC)	2023 - 2025
Assessment of social skills in adolescents and young adults with rare neurodevelopmental diseases	Beck Youth Inventories (BYI)	2023 - 2025

Collaborators and Investigators

• Sponsor: Imagine Institute

Study record dates

Study Major Dates

• Study Start (Actual): May 1, 2024
• Primary Completion (Actual): October 17, 2025
• Study Completion (Actual): October 17, 2025

Study Registration Dates

• First Submitted: April 26, 2024
• First Submitted That Met QC Criteria: September 24, 2024
• First Posted (Actual): September 25, 2024

Study Record Updates

• Last Update Posted (Actual): November 19, 2025
• Last Update Submitted That Met QC Criteria: November 18, 2025
• Last Verified: November 1, 2025

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Mental Disorders; Pathologic Processes; Disease Attributes; Pathological Conditions, Signs and Symptoms; Neurodevelopmental Disorders; Rare Diseases
• Other Study ID Numbers: HJ-23-PEERS-MRND

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No