Vitamin D Status Fluctuations Over One Academic Year in Students

Annual Fluctuation of Vitamin D Nutritional Status in Students and Its Association with the Occurrence of Inflammation, Depressive States, and Cognitive Abilities

The main objective of the study is to assess changes in the concentration of vitamin D metabolite in serum throughout the academic year and to examine its relationship with the occurrence of inflammation indicators, dietary habits, nutritional status, severity of depressive states, and cognitive abilities in a group of students. An additional objective will be to assess the relationship between the genotype in the CYP2R1 gene and the concentration of 25(OH) vitamin D.

Study Overview

• Status: Active, not recruiting
• Conditions: Vitamin D Deficiency
• Intervention / Treatment: Other: Observention of vitamin D

• Study Type: Observational
• Enrollment (Estimated): 70

Contacts and Locations

Study Locations

• Poland
  • Poznań, Poland, 60-637
    • Poznan University of Life Sciences
  • Wielkopolska
    • Poznan, Wielkopolska, Poland, 60-637
      • Poznan University of Life Sciences

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: Adult
• Accepts Healthy Volunteers: Yes

• Sampling Method: Probability Sample

Study Population

Study population includes students of both sexes at the age of 18-30 years who agree to participate and attend all four study meetings over one academic year. The participants should be in good health condition.

Description

Inclusion Criteria:

• no chronic diseases
• student status
• age 18-30 years

Exclusion Criteria:

• chronic diseases (related to malabsorption, kidney and liver diseases)
• not active student status
• age <18 and >30 years

Study Plan

How is the study designed?

Number of groups / cohorts

1

Cohorts and Interventions

Group / Cohort	Intervention / Treatment
University students	Other: Observention of vitamin D; It is an observational study

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Vitamin D concentration	Measurement of 25(OH) vitamin D in serum at four points over an academic year	01.10.2024-01.10.2025

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Inflammation status measured with CRP		01.10.2024-01.10.2025
Depressive symptoms	The magnitude of depressive symptoms over an academic year	01.10.2024-01.10.2025
Cognitive functions		01.10.2024-01.10.2025
Body composition		01.10.2024-01.10.2025
Dietary intake of vitamin D		01.10.2024-01.10.2025
CYP2R1 genotype		01.10.2024-01.10.2025

Collaborators and Investigators

• Sponsor: Poznan University of Life Sciences
• Investigators: Principal Investigator: Emilia Zawieja, PhD, Poznan University of Life Sciences

Study record dates

Study Major Dates

• Study Start (Actual): October 1, 2024
• Primary Completion (Estimated): July 31, 2025
• Study Completion (Estimated): August 31, 2025

Study Registration Dates

• First Submitted: September 3, 2024
• First Submitted That Met QC Criteria: November 5, 2024
• First Posted (Actual): November 6, 2024

Study Record Updates

• Last Update Posted (Actual): November 6, 2024
• Last Update Submitted That Met QC Criteria: November 5, 2024
• Last Verified: June 1, 2024

More Information

Terms related to this study

• Additional Relevant MeSH Terms: Nutrition Disorders; Avitaminosis; Deficiency Diseases; Malnutrition; Vitamin D Deficiency; Physiological Effects of Drugs; Bone Density Conservation Agents; Micronutrients; Vitamins; Vitamin D
• Other Study ID Numbers: VITDstud

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No
• product manufactured in and exported from the U.S.: No