Postoperative Arrhythmia and Preoperative Cardiac Function

May 22, 2025 updated by: National Taiwan University Clinical Trial Center, National Taiwan University Hospital

A Prospective Study on the Association of Perioperative Echocardiographic Parameters and Other Risk Factors With Postoperative Atrial Fibrillation

This study aims to investigate the association between echocardiographic parameters-including preoperative cardiac echo, as well as postoperative follow-up echocardiography and other associated parameters-and the risk factors related to postoperative arrhythmia

Study Overview

Status

Not yet recruiting

Conditions

Intervention / Treatment

Detailed Description

Postoperative atrial fibrillation (POAF), defined as newly onset atrial fibrillation occurring during hospitalization, is a common complication following cardiac surgery, affecting approximately 20-30% of patients. Studies have shown that patients who develop POAF experience longer hospital stays, incur higher medical costs, and have increased rates of stroke- and heart failure-related complications, as well as higher risks of readmission and mortality.

POAF is generally believed to result from acute perioperative triggers acting on preexisting structural abnormalities of the atria or ventricles. However, the echocardiographic predictors of POAF remain poorly understood. While previous studies have examined the association between preoperative transthoracic echocardiography (TTE)-assessed left atrial and left ventricular function and the development of POAF, the detailed relationship between intraoperative transesophageal echocardiography (TEE)-assessed atrial and ventricular function, its intraoperative changes, and POAF remains insufficiently explored.

This study aims to investigate the association between echocardiographic parameters-including preoperative TTE and TEE, as well as postoperative follow-up parameters-and the risk factors related to POAF.

Study Type

Observational

Enrollment (Estimated)

200

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

patients undergoing cardiac surgery

Description

Inclusion Criteria:

  • patients receiving cardiac surgery

Exclusion Criteria:

  • preoperative arrhythmia

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
patients with postoperative arrhythmia
patients with postoperative arrhythmia after cardiac surgery
Other: No Interventions
this is an observational cohort study. There was no intervention.
patients without postoperative arrhythmia
patients without postoperative arrhythmia after cardiac surgery
Other: No interventions
No interventions in this study. This study is an observational study.

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
The occurrence of postoperative arrhythmia
Time Frame: postoperative 1 years
postoperative arrhythmia after cardiac surgery
postoperative 1 years

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

National Taiwan University Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

May 26, 2025

Primary Completion (Estimated)

December 31, 2030

Study Completion (Estimated)

December 31, 2031

Study Registration Dates

First Submitted

May 22, 2025

First Submitted That Met QC Criteria

May 22, 2025

First Posted (Actual)

May 31, 2025

Study Record Updates

Last Update Posted (Actual)

May 31, 2025

Last Update Submitted That Met QC Criteria

May 22, 2025

Last Verified

May 1, 2025

More Information

Terms related to this study

Keywords

Other Study ID Numbers

  • 202505037RINE

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

IPD Plan Description

Due to ethical issue

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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