Modified Trabeculectomy After Failure of Combined Phaco With GATT

March 3, 2026 updated by: Hassan Lotfy Fahmy, Assiut University

Modified Trabeculectomy for Management of Early Failure of Combined Phaco With GATT or With Goinopuncture

These procedures include deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Since the advent of GATT or phacogoinotomy as MIGS, ab-externo canaloplasty and NPDS have become essentially obsolete. The ab-interno techniques to vasodilate Schlemm's canal and goniotomy have largely replaced ab-externo canaloplasty.

. Although the GATT procedure and phacogoinotomy is, minimally invasive methods, yet it needs normal functional collector orifice and not respect physiological function of trabecular meshwork,8 as these procedures depend mainly on incision and damage of trabecular meshwork360 degree in GATT 120 in goniotomy, the main disadvantage of these procedures it is not so suitable for narrow angle glaucoma and have many complications as post operative hyphemia with IOP spike, PAS, corneal injury and create cyclodialysis Moreover trabecular meshwork and Schlemm's canal are vital structures can repair themselves through limbal stem cells or even peripheral iris can cover the incision as the part of repair. The main disadvantage is that the trabeculectomy should not be relied upon when the target IOP is in the low teens. Also, these procedures are expensive and need a long learning curve, hyphemia can prevent completion of the operation.

Study Type

Interventional

Enrollment (Estimated)

20

Phase

  • Not Applicable

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Locations

  • Egypt
      • Asyut, Egypt, 71111
        • Recruiting
        • Assiut univercity
        • Contact:

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Description

Inclusion Criteria:

  • All patients had combined phaco surgery with GATT.
  • All patients had phaco with goinopuncture.

Exclusion Criteria:

  • Healthy patient.
  • No history of phaco surgery with GATT or goinopuncture.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Primary Purpose: Treatment
  • Allocation: N/A
  • Interventional Model: Single Group Assignment
  • Masking: None (Open Label)

Arms and Interventions

Participant Group / Arm
Intervention / Treatment
Experimental: Modified Trabeculectomy
failure of combined phaco with GATT
Procedure: Modified trabeculectomy
deep non-penetrating sclerectomy, viscocanalostomy, and small incision trabeculectomy, avoiding Tenon's capsule

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
IOP
Time Frame: 24 hours
Intraocular pressure measurement
24 hours

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Assiut University

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Estimated)

April 1, 2026

Primary Completion (Estimated)

April 1, 2027

Study Completion (Estimated)

April 1, 2027

Study Registration Dates

First Submitted

March 3, 2026

First Submitted That Met QC Criteria

March 3, 2026

First Posted (Actual)

March 6, 2026

Study Record Updates

Last Update Posted (Actual)

March 6, 2026

Last Update Submitted That Met QC Criteria

March 3, 2026

Last Verified

March 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 17203288

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Glaucoma

Clinical Trials on Modified trabeculectomy

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Chile

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe