The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores

May 6, 2026 updated by: Antalya Training and Research Hospital

The Effect of Paravertebral Block, Intertransverse Block, and Erector Spinae Plane Block on Postoperative Opioid Consumption and Pain Scores in Video-assisted Thoracic Surgery: a Prospective Observational Study

This present study aims is to compare the effects of ultrasound-guided paravertebral block, intertransverse process block, and erector spinae plane block on postoperative opioid consumption, and pain scores in patients undergoing VATS.

Study Overview

Status

Recruiting

Conditions

Intervention / Treatment

Detailed Description

Video-assisted thoracic surgery (VATS) has become increasingly popular in Thoracic Surgery due to faster recovery and less postoperative pain compared to thoracotomy. However, although VATS has been reported to cause less postoperative pain than thoracotomy, it has also been shown to significantly increase the risk of acute and chronic postoperative pain, which negatively impacts postoperative pain recovery. Inadequate postoperative pain management can reduce the quality of a patient's recovery and increase the risk of postoperative pulmonary complication. Therefore, controlling pain in patients undergoing VATS is key to ensuring early mobilisation, and minimising the risk of pulmonary complications. Regional anaesthesia techniques are an important part of multimodal analgesia approach in patients undergoing VATS. The aim of the present study is to compare the effects of ultrasound-guided regional anaesthesia techniques on postoperative opioid consumption, and pain scores in patients undergoing VATS.

Study Type

Observational

Enrollment (Estimated)

96

Contacts and Locations

This section provides the contact details for those conducting the study, and information on where this study is being conducted.

Study Contact

Study Contact Backup

  • Name: Batuhan Kilic
  • Phone Number: +905319001549

Study Locations

  • Turkey (Türkiye)
    • Muratpaşa
      • Antalya, Muratpaşa, Turkey (Türkiye)
        • Recruiting
        • University of Health Sciences, Antalya Training and Research Hospital

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

  • Adult
  • Older Adult

Accepts Healthy Volunteers

No

Sampling Method

Non-Probability Sample

Study Population

It is planned to include ASA score I-III adult patients who are planned to undergo elective VATS

Description

Inclusion Criteria:

  • aged 18-75 years
  • American Society of Anaesthesiology (ASA) score I-III
  • body mass index (BMI) <35kg/m2
  • scheduled for elective VATS

Exclusion Criteria:

  • ASA score ≥4
  • BMI ≥35 kg/m2
  • declining to give written informed consent
  • controendications for block application
  • inability to undergo block application
  • history neurological disease or peripheral nerve disease
  • history of chronic opioid use
  • history of severe liver or kidney failure
  • patients admitted to the intensive care unit postoperatively intubated

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Erector spinae plane block group
Before the surgery, ultrasoud-guided erector spinae plane block will be performed
Other: Erector spinae plane block group
Before the surgery, ultrasoud-guided erector spinae plane block will be performed before the surgery under standart anaesthesia monitoring
Paravertebral block group
Before the surgery, ultrasoud-guided paravertebral block will be performed
Other: Paravertebral block group
Before the surgery, ultrasoud-guided paravertebral block will be performed before the surgery under standart anaesthesia monitoring
İntertransverse process block group
Before the surgery, ultrasoud-guided intertransverse process block will be performed
Other: İntertransverse process block group
Before the surgery, ultrasoud-guided intertransverse process block will be performed before the surgery under standart anaesthesia monitoring

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative opioid consumption
Time Frame: 24 hours
All patients will receive a standard patient analgesia (PCA) protocol after operation. The postoperative opioid consumption will only be recorded.
24 hours

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Postoperative Numerical Rating Scale (NRS) pain scores
Time Frame: postoperative 24 hours
The postoperative pain intensity will be assessed with the Numerical Rating Scale (NRS) score (0=no pain; 10=most severe pain).
postoperative 24 hours
Chronic pain
Time Frame: 3 months
Patients will be telephoned 3 months after the surgery and the presence, localization, intensity of the pain , its character, and its relation with rest and/or activity will be recorded by asking only verbally.
3 months

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Antalya Training and Research Hospital

Investigators

  • Principal Investigator: Sadik Ozmen, University of Health Sciences, Antalya Training and Research Hospital
  • Principal Investigator: Batuhan Kılıc, University of Health Sciences, Antalya Training and Research Hospital
  • Principal Investigator: Hacer Boztepe Yesilcay, University of Health Sciences, Antalya Training and Research Hospital

Publications and helpful links

The person responsible for entering information about the study voluntarily provides these publications. These may be about anything related to the study.

General Publications

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start (Actual)

May 4, 2026

Primary Completion (Estimated)

October 4, 2026

Study Completion (Estimated)

November 4, 2026

Study Registration Dates

First Submitted

April 21, 2026

First Submitted That Met QC Criteria

May 6, 2026

First Posted (Actual)

May 11, 2026

Study Record Updates

Last Update Posted (Actual)

May 11, 2026

Last Update Submitted That Met QC Criteria

May 6, 2026

Last Verified

April 1, 2026

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • 7/24

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

NO

Drug and device information, study documents

Studies a U.S. FDA-regulated drug product

No

Studies a U.S. FDA-regulated device product

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

Clinical Trials on Thoracic Surgery

Clinical Trials on Erector spinae plane block group

Search Similar Trials

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mali

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations

Subscribe