Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[InterventionSearch] Nelfinavir mesylate
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NCTID/Status
Study
Last Changed
1
NCT03077451
Recruiting
Recruiting
Nelfinavir Mesylate in Treating Patients With Kaposi Sarcoma
Conditions: Recurrent Kaposi Sarcoma; Skin Kaposi Sarcoma
Intervention: Laboratory Biomarker Analysis, Nelfinavir Mesylate
Conditions: Recurrent Kaposi Sarcoma; Skin Kaposi Sarcoma
Intervention: Laboratory Biomarker Analysis, Nelfinavir Mesylate
July 1, 2019
2
NCT02080416
Terminated
Terminated
Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors
Conditions: Non-Hodgkin Lymphoma; Hodgkin Lymphoma; Kaposi Sarcoma; Gastric Cancer; Nasopharyngeal Cancer; EBV; Castleman Disease
Intervention: Nelfinavir
Conditions: Non-Hodgkin Lymphoma; Hodgkin Lymphoma; Kaposi Sarcoma; Gastric Cancer; Nasopharyngeal Cancer; EBV; Castleman Disease
Intervention: Nelfinavir
June 8, 2016
3
NCT02066311
Completed
Completed
Nelfinavir in Systemic Lupus Erythematosus
Conditions: Systemic Lupus Erythematosus
Intervention: Nelfinavir
Conditions: Systemic Lupus Erythematosus
Intervention: Nelfinavir
July 25, 2018
4
NCT01925378
Recruiting
Recruiting
A Phase II Single-arm Intervention Trial of Nelfinavir in Patients With Grade 2/3 or 3 Cervical Intraepithelial Neoplasia
Conditions: Cervical Dysplasia
Intervention: Nelfinavir
Conditions: Cervical Dysplasia
Intervention: Nelfinavir
February 22, 2017
5
NCT00704600
Completed
Completed
Nelfinavir, a Phase I/Phase II Rectal Cancer Study
Conditions: Colorectal Cancer; Colorectal Carcinoma; Colorectal Tumors; Neoplasms, Colorectal
Intervention: Nelfinavir
Conditions: Colorectal Cancer; Colorectal Carcinoma; Colorectal Tumors; Neoplasms, Colorectal
Intervention: Nelfinavir
December 5, 2014
6
NCT01065844
Completed
Completed
Nelfinavir in Recurrent Adenoid Cystic Cancer of the Head and Neck
Conditions: Carcinoma, Adenoid Cystic; Head and Neck Neoplasms
Intervention: Nelfinavir
Conditions: Carcinoma, Adenoid Cystic; Head and Neck Neoplasms
Intervention: Nelfinavir
September 24, 2019
7
NCT01447589
Withdrawn
Withdrawn
Radical Lung Radiotherapy Plus Nelfinavir
Conditions: Lung Cancer
Intervention: Nelfinavir, Radical Radiotherapy
Conditions: Lung Cancer
Intervention: Nelfinavir, Radical Radiotherapy
June 22, 2016
8
NCT00246610
Completed
Completed
Safety Of VIRACEPT® 625mg Administered To HIV-Infected Women During Pregnancy
Conditions: HIV Infection
Intervention: Nelfinavir Mesylate, 625 Mg
Conditions: HIV Infection
Intervention: Nelfinavir Mesylate, 625 Mg
April 26, 2011
9
NCT03422874
Withdrawn
Withdrawn
Dose Escalation Study of Nelfinavir Plus MLN9708 in Patients With Advanced Solid Tumors or Lymphoma
Conditions: Neoplasms; Lymphoma
Intervention: MLN9708, Nelfinavir
Conditions: Neoplasms; Lymphoma
Intervention: MLN9708, Nelfinavir
January 30, 2018
10
NCT01728779
Active, not recruiting
Active, not recruiting
Stereotactic Body Radiation With Nelfinavir for Oligometastases
Conditions: Oligometastases
Intervention: Nelfinavir, Stereotactic Body Radiation (SBRT)
Conditions: Oligometastases
Intervention: Nelfinavir, Stereotactic Body Radiation (SBRT)
November 22, 2019
11
NCT00791336
Terminated
Terminated
Study to Evaluate Using Nelfinavir With Chemoradiation for Non-small Cell Lung Cancer
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Nelfinavir
Conditions: Carcinoma, Non-Small-Cell Lung
Intervention: Nelfinavir
June 29, 2017
12
NCT01164709
Completed
Completed
Nelfinavir Mesylate and Bortezomib in Treating Patients With Relapsed or Progressive Advanced Hematologic Cancer
Conditions: Leukemia; Lymphoma; Mature T-cell and Nk-cell Neoplasms; Multiple Myeloma and Plasma Cell Neoplasm
Intervention: Bortezomib, Nelfinavir Mesylate
Conditions: Leukemia; Lymphoma; Mature T-cell and Nk-cell Neoplasms; Multiple Myeloma and Plasma Cell Neoplasm
Intervention: Bortezomib, Nelfinavir Mesylate
May 14, 2019
13
NCT01079286
Completed
Completed
Study of Nelfinavir and Temsirolimus in Patients With Advanced Cancers
Conditions: Renal Cell Cancer; Cancer
Intervention: Nelfinavir And Temsirolimus
Conditions: Renal Cell Cancer; Cancer
Intervention: Nelfinavir And Temsirolimus
July 12, 2013
14
NCT03829020
Recruiting
Recruiting
Metformin and Nelfinavir in Treating Patients With Relapsed and/or Refractory Multiple Myeloma
Conditions: Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
Intervention: Bortezomib, Metformin Hydrochloride, Nelfinavir Mesylate
Conditions: Recurrent Plasma Cell Myeloma; Refractory Plasma Cell Myeloma
Intervention: Bortezomib, Metformin Hydrochloride, Nelfinavir Mesylate
December 4, 2019
15
NCT01086332
Terminated
Terminated
Evaluation of Nelfinavir and Chemoradiation for Pancreatic Cancer
Conditions: Pancreatic Neoplasms
Intervention: Nelfinavir, Gemcitabine
Conditions: Pancreatic Neoplasms
Intervention: Nelfinavir, Gemcitabine
November 8, 2018
16
NCT01555281
Active, not recruiting
Active, not recruiting
Nelfinavir and Lenalidomide/Dexamethasone in Progressive Multiple Myeloma
Conditions: Multiple Myeloma
Intervention: Nelfinavir, Lenalidomide, Dexamethasone
Conditions: Multiple Myeloma
Intervention: Nelfinavir, Lenalidomide, Dexamethasone
May 20, 2019
17
NCT02188537
Completed
Completed
Nelfinavir as Bortezomib-sensitizing Drug in Patients With Proteasome Inhibitor-nonresponsive Myeloma
Conditions: Myeloma
Intervention: Nelfinavir, Bortezomib, Dexamethasone
Conditions: Myeloma
Intervention: Nelfinavir, Bortezomib, Dexamethasone
June 24, 2019
18
NCT01108666
Terminated
Terminated
Proton Beam Radiation With Concurrent Chemotherapy and Nelfinavir for Inoperable Stage III Non Small Cell Lung Cancer (NSCLC)
Conditions: Non Small Cell Lung Cancer
Intervention: Nelfinavir
Conditions: Non Small Cell Lung Cancer
Intervention: Nelfinavir
May 30, 2019
19
NCT00002165
Completed
Completed
June 23, 2005
20
NCT00002164
Completed
Completed
Phase I Study of Safety, Tolerability, and Pharmacokinetics of Viracept in HIV-1 Infected Children and Exposed Infants
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate
June 23, 2005
21
NCT00694837
Completed
Completed
Study With Nelfinavir and Combined Radiochemotherapy for Glioblastoma
Conditions: Glioblastoma
Intervention: Nelfinavir
Conditions: Glioblastoma
Intervention: Nelfinavir
April 9, 2015
22
NCT00002169
Completed
Completed
A Study of Viracept in AIDS Patients With Cytomegalovirus Retinitis
Conditions: Cytomegalovirus Retinitis; HIV Infections
Intervention: Nelfinavir Mesylate
Conditions: Cytomegalovirus Retinitis; HIV Infections
Intervention: Nelfinavir Mesylate
June 23, 2005
23
NCT00002171
Completed
Completed
A Study of Viracept in HIV-Positive Women
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate
June 23, 2005
24
NCT00002170
Completed
Completed
A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)
Conditions: Mycobacterium Avium-Intracellulare Infection; HIV Infections
Intervention: Nelfinavir Mesylate
Conditions: Mycobacterium Avium-Intracellulare Infection; HIV Infections
Intervention: Nelfinavir Mesylate
June 23, 2005
25
NCT00002185
Completed
Completed
A Pilot, Open-Label, Phase II, Randomized Study to Determine the Effects of Viracept on the Outcome of Cutaneous and Mucosal KS in AIDS Patients With CD4 <= 500 Cells/mm3
Conditions: Sarcoma, Kaposi; HIV Infections
Intervention: Nelfinavir Mesylate
Conditions: Sarcoma, Kaposi; HIV Infections
Intervention: Nelfinavir Mesylate
June 23, 2005
26
NCT01445106
Completed
Completed
A Phase I Trial of Nelfinavir (Viracept ) in Adults With Solid Tumors
Conditions: Solid Tumors
Intervention: Nelfinavir, Nelfinavir Mesylate
Conditions: Solid Tumors
Intervention: Nelfinavir, Nelfinavir Mesylate
December 4, 2019
27
NCT03256916
Recruiting
Recruiting
Radiosensitizing Effect of Nelfinavir in Locally Advanced Carcinoma of Cervix
Conditions: Carcinoma Cervix, Stage III
Intervention: Nelfinavir, Cisplatin, Pelvic EBRT And Brachytherapy
Conditions: Carcinoma Cervix, Stage III
Intervention: Nelfinavir, Cisplatin, Pelvic EBRT And Brachytherapy
June 22, 2019
28
NCT04169763
Not yet recruiting
Not yet recruiting
Nelfinavir, Cisplatin, and External Beam Radiation Therapy for the Treatment of Locally Advanced Vulvar Cancer That Cannot Be Removed by Surgery
Conditions: Stage II Vulvar Cancer AJCC v8; Stage III Vulvar Cancer AJCC v8; Stage IIIA Vulvar Cancer AJCC v8; Stage IIIB Vulvar Cancer AJCC v8; Stage IIIC Vulvar Cancer AJCC v8; Stage IVA Vulvar Cancer AJCC v8
Intervention: Cisplatin, External Beam Radiation Therapy, Nelfinavir
Conditions: Stage II Vulvar Cancer AJCC v8; Stage III Vulvar Cancer AJCC v8; Stage IIIA Vulvar Cancer AJCC v8; Stage IIIB Vulvar Cancer AJCC v8; Stage IIIC Vulvar Cancer AJCC v8; Stage IVA Vulvar Cancer AJCC v8
Intervention: Cisplatin, External Beam Radiation Therapy, Nelfinavir
November 18, 2019
29
NCT03050060
Suspended
Suspended
Image Guided Hypofractionated Radiation Therapy, Nelfinavir Mesylate, Pembrolizumab, Nivolumab and Atezolizumab in Treating Patients With Advanced Melanoma, Lung, or Kidney Cancer
Conditions: Metastatic Kidney Carcinoma; Recurrent Melanoma; Recurrent Lung Non-Small Cell Carcinoma; Recurrent Renal Cell Carcinoma; Stage IV Cutaneous Melanoma AJCC v6 and v7; Stage IV Non-Small Cell Lung Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7
Intervention: Atezolizumab, Hypofractionated Radiation Therapy, Laboratory Biomarker Analysis, Nelfinavir Mesylate, Nivolumab, Pembrolizumab, Nelfinavir
Conditions: Metastatic Kidney Carcinoma; Recurrent Melanoma; Recurrent Lung Non-Small Cell Carcinoma; Recurrent Renal Cell Carcinoma; Stage IV Cutaneous Melanoma AJCC v6 and v7; Stage IV Non-Small Cell Lung Cancer AJCC v7; Stage IV Renal Cell Cancer AJCC v7
Intervention: Atezolizumab, Hypofractionated Radiation Therapy, Laboratory Biomarker Analysis, Nelfinavir Mesylate, Nivolumab, Pembrolizumab, Nelfinavir
May 15, 2019
30
NCT00205283
Completed
Completed
Nelfinavir and M8 Drug-level Monitoring in HIV-1 Infection
Conditions: HIV Infections
Intervention: Nelfinavir
Conditions: HIV Infections
Intervention: Nelfinavir
March 20, 2019
31
NCT00002201
Completed
Completed
A Study of Ritonavir (ABT-538) When Used With Nelfinavir in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Ritonavir, Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Ritonavir, Nelfinavir Mesylate
February 19, 2009
32
NCT00002375
Completed
Completed
Safety and Effectiveness of Giving Indinavir and Nelfinavir to HIV-Infected Patients
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Indinavir Sulfate, Nelfinavir Mesylate
June 23, 2005
33
NCT00233948
Terminated
Terminated
Nelfinavir Mesylate in Treating Patients With Recurrent, Metastatic, or Unresectable Liposarcoma
Conditions: Adult Liposarcoma; Recurrent Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma
Conditions: Adult Liposarcoma; Recurrent Adult Soft Tissue Sarcoma; Stage III Adult Soft Tissue Sarcoma; Stage IV Adult Soft Tissue Sarcoma
March 30, 2015
34
NCT00312182
Completed
Completed
April 9, 2009
35
NCT00000893
Completed
Completed
Safety, Tolerability, and Anti-HIV Activity of DMP 266 (Efavirenz) in Combination With Nelfinavir in HIV-Positive Children
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate, Efavirenz
Conditions: HIV Infections
Intervention: Nelfinavir Mesylate, Efavirenz
June 2, 2015
36
NCT00346619
Completed
Completed
Determining the Amount of Time Needed for Nelfinavir to Boost the Immune System in Adults
Conditions: Immune Response
Intervention: Nelfinavir
Conditions: Immune Response
Intervention: Nelfinavir
January 19, 2010
37
NCT01020292
Completed
Completed
A Trial of the Protease Inhibitor Nelfinavir and Concurrent Radiation and Temozolomide in Patients With WHO Grade IV Glioma
Conditions: Glioma
Intervention: Nelfinavir
Conditions: Glioma
Intervention: Nelfinavir
April 10, 2019
38
NCT01485731
Completed
Completed
Safety Study of Nelfinavir + Cisplatin + Pelvic Radiation Therapy to Treat Cervical Cancer
Conditions: Cervical Cancer
Intervention: Nelfinavir, Cisplatin, Pelvic External Beam Radiation Therapy, Brachytherapy, Pharmacokinetic Sampling, Cervical Biopsy, Pelvic Examination, Pap Smear, Audiogram, Proctoscopy, Cytoscopy, Renal Ultrasound, CT Scan, Whole Body PET/CT Scan
Conditions: Cervical Cancer
Intervention: Nelfinavir, Cisplatin, Pelvic External Beam Radiation Therapy, Brachytherapy, Pharmacokinetic Sampling, Cervical Biopsy, Pelvic Examination, Pap Smear, Audiogram, Proctoscopy, Cytoscopy, Renal Ultrasound, CT Scan, Whole Body PET/CT Scan
June 1, 2015
39
NCT00006211
Completed
Completed
A Study of Capravirine Plus VIRACEPT Plus Two Nucleoside Reverse Transcriptase Inhibitors in HIV-Infected Patients Who Failed Previous Anti-HIV Treatments
Conditions: HIV Infections
Intervention: Capravirine, Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Capravirine, Nelfinavir Mesylate
June 23, 2005
40
NCT00004985
Completed
Completed
Combination Treatment Using Capravirine (AG1549), Nelfinavir, and Two Nucleoside Reverse Transcriptase Inhibitors in HIV Patients Who Failed Initial Combination Therapy
Conditions: HIV Infections
Conditions: HIV Infections
June 23, 2005
41
NCT00457665
Completed
Completed
Mechanisms of Lipodystrophy in HIV-Infected Pateints
Conditions: HIV Infections
Intervention: Nelfinavir, Efavirenz
Conditions: HIV Infections
Intervention: Nelfinavir, Efavirenz
May 8, 2019
42
NCT00251030
Completed
Completed
A Study To Estimate The Effect Of Omeprazole On The Pharmacokinetics Of Nelfinavir In Healthy Subjects
Conditions: Healthy Volunteers
Intervention: Nelfinavir And Omeprazole
Conditions: Healthy Volunteers
Intervention: Nelfinavir And Omeprazole
February 13, 2009
43
NCT00028067
Terminated
Terminated
A Comparison of Atazanavir and Nelfinavir, Each in Combination With 2 NRTIs, in Patients Who Have Failed Treatments Without a Protease Inhibitor
Conditions: HIV Infections
Intervention: Atazanavir, Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Atazanavir, Nelfinavir Mesylate
April 28, 2011
44
NCT02363829
Recruiting
Recruiting
A Study of Nelfinavir Added to Cisplatin Chemotherapy Concurrent With Pelvic Radiation for Locally Advanced Cervical Cancer (II-IVA)
Conditions: Uterine Cervix Cancer
Intervention: Nelfinavir, Cisplatin
Conditions: Uterine Cervix Cancer
Intervention: Nelfinavir, Cisplatin
September 26, 2018
45
NCT00002215
Completed
Completed
A Randomized, Double-Blind Study of MKC-442 Combined With Viracept in Patients Who Are Epivir + Retrovir Experienced and Are Protease Inhibitor- and Non-Nucleoside Reverse Transcriptase Inhibitor-Naive
Conditions: HIV Infections
Conditions: HIV Infections
June 23, 2005
46
NCT00915694
Terminated
Terminated
Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme
Conditions: Brain and Central Nervous System Tumors
Conditions: Brain and Central Nervous System Tumors
April 22, 2019
47
NCT00650637
Terminated
Terminated
A Study to Determine Effective Prophylaxis and Treatment of Nelfinavir-Associated Diarrhea
Conditions: Diarrhea
Intervention: Calcium Carbonate, Nelfinavir, Lamivudine, Loperamide, Calcium Carbonate Not Administered, Nelfinavir, Lamivudine + Zidovudine
Conditions: Diarrhea
Intervention: Calcium Carbonate, Nelfinavir, Lamivudine, Loperamide, Calcium Carbonate Not Administered, Nelfinavir, Lamivudine + Zidovudine
June 3, 2011
48
NCT00541463
Completed
Completed
A Study of Indinavir Plus Ritonavir Plus Two NRTIs vs. Nelfinavir Plus Two NRTIs in HIV Positive Patients (0639-112)(COMPLETED)
Conditions: HIV Infections
Intervention: MK0639, Indinavir Sulfate / Duration Of Treatment: 48 Weeks, Comparator: Nelfinavir Mesylate / Duration Of Treatment: 48 Weeks
Conditions: HIV Infections
Intervention: MK0639, Indinavir Sulfate / Duration Of Treatment: 48 Weeks, Comparator: Nelfinavir Mesylate / Duration Of Treatment: 48 Weeks
February 16, 2017
49
NCT00004999
Suspended
Suspended
Effectiveness of a New Anti-HIV Drug (AG1549) Plus Viracept (Nelfinavir) Plus Combivir (Zidovudine/Lamivudine) in HIV-Infected Patients
Conditions: HIV Infections
Intervention: Lamivudine/Zidovudine, Capravirine, Nelfinavir Mesylate
Conditions: HIV Infections
Intervention: Lamivudine/Zidovudine, Capravirine, Nelfinavir Mesylate
June 23, 2005
50
NCT01959672
Completed
Completed
Combination Chemotherapy With or Without Oregovomab Followed by Stereotactic Body Radiation Therapy and Nelfinavir Mesylate in Treating Patients With Locally Advanced Pancreatic Cancer
Conditions: Pancreatic Adenocarcinoma; Resectable Pancreatic Carcinoma; Stage I Pancreatic Cancer; Stage IA Pancreatic Cancer; Stage IB Pancreatic Cancer; Stage II Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer
Intervention: 4-Dimensional Computed Tomography, Fluorouracil, Gemcitabine Hydrochloride, Laboratory Biomarker Analysis, Leucovorin Calcium, Nelfinavir Mesylate, Oregovomab, Stereotactic Body Radiation Therapy, Therapeutic Conventional Surgery
Conditions: Pancreatic Adenocarcinoma; Resectable Pancreatic Carcinoma; Stage I Pancreatic Cancer; Stage IA Pancreatic Cancer; Stage IB Pancreatic Cancer; Stage II Pancreatic Cancer; Stage IIA Pancreatic Cancer; Stage IIB Pancreatic Cancer; Stage III Pancreatic Cancer
Intervention: 4-Dimensional Computed Tomography, Fluorouracil, Gemcitabine Hydrochloride, Laboratory Biomarker Analysis, Leucovorin Calcium, Nelfinavir Mesylate, Oregovomab, Stereotactic Body Radiation Therapy, Therapeutic Conventional Surgery
October 27, 2019
Last Updated
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Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
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In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
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In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
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Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
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conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
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Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.