Clinical Trials: SEARCH[STUDY] TILT[STUDY:STUDY-FIRST-POSTED] ( Infant Newborn Diseases [STUDY:ALL-FIELDS] )
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#
NCTID/Status
Study
Last Changed
1
NCT02643472
Completed
Completed
GPS (Giving Parents Support): Parent Navigation After NICU Discharge
Conditions: Premature Birth of Newborn; Family; Immature Newborn; Newborn Morbidity; Infant Newborn Disease
Intervention: Parent Navigator, Care Notebook
Conditions: Premature Birth of Newborn; Family; Immature Newborn; Newborn Morbidity; Infant Newborn Disease
Intervention: Parent Navigator, Care Notebook
June 20, 2019
2
NCT01289808
Terminated
Terminated
Reduced Infant Response To A Routine Care Procedure After Glucose 25% Analgesia
Conditions: Infant; Newborn Diseases
Intervention: Glucose 25%, Glucose 25%
Conditions: Infant; Newborn Diseases
Intervention: Glucose 25%, Glucose 25%
January 6, 2012
3
NCT03024710
Completed
Completed
Promotion of Complimentary Feeding Practices in Bangladesh
Conditions: Growth Disorders
Intervention: Intervention Cluster
Conditions: Growth Disorders
Intervention: Intervention Cluster
January 19, 2017
4
NCT01603888
Completed
Completed
Molecular Forms of Plasma and Urinary B-type Natriuretic Peptide and Its N-terminal Prohormone in Health and Disease in Pediatric Cardiology
Conditions: Heart Disease; Health
Intervention: No Intervention
Conditions: Heart Disease; Health
Intervention: No Intervention
November 26, 2017
5
NCT03920748
Recruiting
Recruiting
Evaluation of the Relationship Between Airway Measurements and Laryngoscopic View in Newborn and Infants
Conditions: Anesthesia Intubation Complication; Infant; Newborn
Intervention: Group D, Group E
Conditions: Anesthesia Intubation Complication; Infant; Newborn
Intervention: Group D, Group E
April 18, 2019
6
NCT01888471
Completed
Completed
Feasibility Study for Identifying Anti Capsular Antibody Protection Against Invasive Group B Streptococcus (GBS) Disease in Newborns of 0-6 Days Age (Early Onset Disease [EOD]) as Well as Among Infants of 7-90 Days Age (Late Onset Disease [LOD])
Conditions: Streptococcus Agalactiae
Intervention: Blood Sample, Vaginal Swab Sample
Conditions: Streptococcus Agalactiae
Intervention: Blood Sample, Vaginal Swab Sample
July 17, 2019
7
NCT02099149
Withdrawn
Withdrawn
Antibody Levels Associated With Reduced Risk of Invasive Group B Streptococcus Disease in Infants Aged Less Than 90 Days
Conditions: Invasive Group B Streptococcus Disease
Conditions: Invasive Group B Streptococcus Disease
July 23, 2014
8
NCT01108965
Completed
Completed
Study of Shunt Flow Sensor Accuracy in Extra-ventricular Drains.
Conditions: Hydrocephalus; Nervous System Diseases; Infant, Newborn Diseases
Conditions: Hydrocephalus; Nervous System Diseases; Infant, Newborn Diseases
May 25, 2016
9
NCT01765205
Completed
Completed
Newborn Screening for Critical Congenital Heart Disease
Conditions: Congenital Cardiovascular Malformation
Intervention: Pulse Oximetry Using The INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter
Conditions: Congenital Cardiovascular Malformation
Intervention: Pulse Oximetry Using The INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter
March 13, 2014
10
NCT00325273
Completed
Completed
Prevention Allergic Disease of Infant With Probiotics During Pregnancy and Neonatal Period
Conditions: Atopic Dermatitis; Allergic Rhinitis; Asthma
Intervention: Lactobacillus Rhamnosus GG
Conditions: Atopic Dermatitis; Allergic Rhinitis; Asthma
Intervention: Lactobacillus Rhamnosus GG
March 16, 2015
11
NCT03923374
Recruiting
Recruiting
Opioid Use Disorder in Pregnancy in Long-Term Maternal/Infant Outcomes
Conditions: Opioid-use Disorder; Opioid Use, Unspecified; Buprenorphine Dependence
Intervention: Subutex / Buprenorphine, Fetal & Neonatal MRI, DNA/Genetic/Pharmacokenetic Blood Draws
Conditions: Opioid-use Disorder; Opioid Use, Unspecified; Buprenorphine Dependence
Intervention: Subutex / Buprenorphine, Fetal & Neonatal MRI, DNA/Genetic/Pharmacokenetic Blood Draws
April 18, 2019
12
NCT03340259
Recruiting
Recruiting
Intestinal Colonization in Newborn Infants With Enterostomy
Conditions: Newborn Infants With Enterostomy by Congenital Malformations of the Gastrointestinal Tract, Necrotizing Enterocolitis and Spontaneous Intestinal Perforation
Intervention: Exposure(s) Of Interest: Enterostomy
Conditions: Newborn Infants With Enterostomy by Congenital Malformations of the Gastrointestinal Tract, Necrotizing Enterocolitis and Spontaneous Intestinal Perforation
Intervention: Exposure(s) Of Interest: Enterostomy
November 8, 2017
13
NCT01610765
Withdrawn
Withdrawn
A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease)
Conditions: Herpes Simplex Virus
Intervention: Novel Antiviral Drug, Placebo
Conditions: Herpes Simplex Virus
Intervention: Novel Antiviral Drug, Placebo
June 6, 2016
14
NCT02178267
Completed
Completed
Probiotics On Resistant Bacteria Colonization In Preterm Receiving Antibiotics
Conditions: Infant, Premature, Diseases
Intervention: Lactobacillus Reuteri (biogai AB, Sweden)
Conditions: Infant, Premature, Diseases
Intervention: Lactobacillus Reuteri (biogai AB, Sweden)
June 27, 2014
15
NCT02215226
Completed
Completed
GBS Sero-correlate of Protection
Conditions: Invasive Group B Streptococcus Disease
Conditions: Invasive Group B Streptococcus Disease
September 12, 2018
16
NCT04032522
Not yet recruiting
Not yet recruiting
Neonatal HIV Early Infant Diagnosis (EID) Versus Standard of Care EID- Long Term Impact on inFant hEalth (LIFE)
Conditions: HIV, Neonatal HIV Early-Infant-Diagnosis (EID), Point-of-Care Testing (PoC)
Intervention: Point-of Care (PoC) Neonatal HIV Early Infant Diagnosis (EID)
Conditions: HIV, Neonatal HIV Early-Infant-Diagnosis (EID), Point-of-Care Testing (PoC)
Intervention: Point-of Care (PoC) Neonatal HIV Early Infant Diagnosis (EID)
July 23, 2019
17
NCT01849120
Completed
Completed
NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery
Conditions: Congenital Heart Disease
Intervention: EQUANOX Advance 8004CB Sensor
Conditions: Congenital Heart Disease
Intervention: EQUANOX Advance 8004CB Sensor
April 12, 2017
18
NCT03985501
Not yet recruiting
Not yet recruiting
DREPAMASSE Study - Evaluation of a Newborn Screening for Sickle Cell Disease by Tandem Mass Spectrometry
Conditions: Sickle Cell Disease; Infant, Newborn, Disease; Drepanocytosis
Intervention: SCD Newborn Screening With The MS/MS Method From Zentech
Conditions: Sickle Cell Disease; Infant, Newborn, Disease; Drepanocytosis
Intervention: SCD Newborn Screening With The MS/MS Method From Zentech
June 12, 2019
19
NCT03253263
Recruiting
Recruiting
A Clinical Efficacy and Safety Study of SHP607 in Preventing Chronic Lung Disease in Extremely Premature Infants
Conditions: Retinopathy of Prematurity (ROP); Intraventricular Hemorrhage; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
Intervention: SHP607
Conditions: Retinopathy of Prematurity (ROP); Intraventricular Hemorrhage; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
Intervention: SHP607
May 29, 2019
20
NCT03655223
Enrolling by invitation
Enrolling by invitation
Early Check: Expanded Screening in Newborns
Conditions: Spinal Muscular Atrophy; Fragile X Syndrome; Fragile X - Premutation
Intervention: Confirmatory Testing
Conditions: Spinal Muscular Atrophy; Fragile X Syndrome; Fragile X - Premutation
Intervention: Confirmatory Testing
December 11, 2018
21
NCT00744419
Completed
Completed
Intravenous (IV) Pantoprazole for Gastroesophageal Reflux Disease (GERD) in Neonates and Infants
Conditions: Gastroesophageal Reflux
Intervention: Pantoprazole
Conditions: Gastroesophageal Reflux
Intervention: Pantoprazole
December 1, 2015
22
NCT02375854
Recruiting
Recruiting
Outcomes of Neonatal Acute Kidney Injury In Premature Infants
Conditions: Acute Kidney Injury; Chronic Kidney Disease
Intervention: Observation
Conditions: Acute Kidney Injury; Chronic Kidney Disease
Intervention: Observation
April 23, 2019
23
NCT02826694
Active, not recruiting
Active, not recruiting
North Carolina Newborn Exome Sequencing for Universal Screening
Conditions: Metabolism, Inborn Errors; Hearing Loss; Hereditary Disease
Intervention: Well Infant, Whole Exome Sequencing, Diagnosed, Whole Exome Sequencing
Conditions: Metabolism, Inborn Errors; Hearing Loss; Hereditary Disease
Intervention: Well Infant, Whole Exome Sequencing, Diagnosed, Whole Exome Sequencing
March 4, 2019
24
NCT03535311
Recruiting
Recruiting
Estimating Insertion Length of Umbilical Catheters in Newborn Infants
Conditions: Infant, Newborn, Diseases
Intervention: Measurement Of Sternal-notch To Umbilicus Distance
Conditions: Infant, Newborn, Diseases
Intervention: Measurement Of Sternal-notch To Umbilicus Distance
July 16, 2018
25
NCT03721640
Recruiting
Recruiting
Evaluation of the Neonatal Autonomic Stress During Intubations Under Propofol in a Population of Premature Infants Under 33 w'GA
Conditions: Hyaline Membrane Disease; Preterm Infant
Intervention: Electrocardiogram
Conditions: Hyaline Membrane Disease; Preterm Infant
Intervention: Electrocardiogram
March 1, 2019
26
NCT02422511
Active, not recruiting
Active, not recruiting
Genomic Sequencing for Childhood Risk and Newborn Illness
Conditions: Hereditary Disease; Genetic Predisposition to Disease
Intervention: Genomic Sequencing, Family History Report
Conditions: Hereditary Disease; Genetic Predisposition to Disease
Intervention: Genomic Sequencing, Family History Report
May 14, 2019
27
NCT00787865
Active, not recruiting
Active, not recruiting
Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease
Conditions: Krabbe Disease
Conditions: Krabbe Disease
December 4, 2018
28
NCT02692326
Completed
Completed
Impact of Cyclic Prolonged Parenteral Nutrition in Neonates
Conditions: Cholestasis in Newborn
Intervention: Cyclic Parenteral Nutrition
Conditions: Cholestasis in Newborn
Intervention: Cyclic Parenteral Nutrition
February 22, 2016
29
NCT01466062
Completed
Completed
Clinical Study of Palivizumab in Japanese Newborns, Infants and Young Children at the Age of 24 Months or Less With Immunocompromised Medical Conditions
Conditions: Respiratory Syncytial Virus Infection
Intervention: Palivizumab
Conditions: Respiratory Syncytial Virus Infection
Intervention: Palivizumab
June 13, 2013
30
NCT03481452
Not yet recruiting
Not yet recruiting
April 2, 2018
31
NCT03956511
Completed
Completed
Integrated Prediction of Extubation Outcome by the Spontaneous Breathing Trial in Newborn Infants
Conditions: Infant, Newborn, Diseases; Airway Morbidity
Intervention: Spontaneous Breathing Trial
Conditions: Infant, Newborn, Diseases; Airway Morbidity
Intervention: Spontaneous Breathing Trial
May 17, 2019
32
NCT01722760
Completed
Completed
Tidal Neonatal NO, Vitamins A and D, and Infant Lung Disease - The AD-ON Study
Conditions: Term Delivery With Preterm Labor, Third Trimester; Term Delivery With Preterm Labor, Unspecified Trimester; Bronchopulmonary Dysplasia
Intervention: Measurements
Conditions: Term Delivery With Preterm Labor, Third Trimester; Term Delivery With Preterm Labor, Unspecified Trimester; Bronchopulmonary Dysplasia
Intervention: Measurements
November 5, 2015
33
NCT00327977
Completed
Completed
Hypoxemia in Infants After Palliative Surgery
Conditions: Congenital Disorders
Conditions: Congenital Disorders
November 25, 2014
34
NCT02781545
Active, not recruiting
Active, not recruiting
Motor Development of Children That Have Surgery as Newborns for Complex Congenital Heart Disease
Conditions: Heart Defects, Congenital
Conditions: Heart Defects, Congenital
July 6, 2019
35
NCT01514253
Unknown status
Unknown status
Reduced Infant Response to a Routine Care Procedure After Glucose 25% Analgesia in Comparison to Materna RTF Stage 1
Conditions: Infant, Newborn, Diseases
Intervention: Glucose 25%, Materna RTF Stage 1, Water For Injection
Conditions: Infant, Newborn, Diseases
Intervention: Glucose 25%, Materna RTF Stage 1, Water For Injection
January 20, 2012
36
NCT01088945
Completed
Completed
Safe Passages: Ensuring Quality Transitions From NICU (Neonatal Intensive Care Unit) to Ambulatory Care
Conditions: Infant, Premature, Diseases
Intervention: Enhanced Discharge Process
Conditions: Infant, Premature, Diseases
Intervention: Enhanced Discharge Process
July 24, 2015
37
NCT01982357
Suspended
Suspended
Measurement of Neonatal Microvascular Hemodynamics Using Non-invasive Optical Technologies
Conditions: Infant, Premature, Diseases
Intervention: Laser Speckle Imaging And Diffuse Optical Spectroscopy
Conditions: Infant, Premature, Diseases
Intervention: Laser Speckle Imaging And Diffuse Optical Spectroscopy
February 21, 2019
38
NCT00136370
Unknown status
Unknown status
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn
Conditions: Infant, Newborn, Diseases; Sepsis; Puerperal Infection
Intervention: Chlorhexidine, Birth Canal Wipe, Sterile Water External Genital Wipe
Conditions: Infant, Newborn, Diseases; Sepsis; Puerperal Infection
Intervention: Chlorhexidine, Birth Canal Wipe, Sterile Water External Genital Wipe
September 21, 2007
39
NCT02270476
Recruiting
Recruiting
Longitudinal Observational Study on the Course of Cystic Fibrosis Lung Disease in Patients Following Newborn Screening
Conditions: Cystic Fibrosis Lung Disease
Conditions: Cystic Fibrosis Lung Disease
May 14, 2018
40
NCT00061828
Recruiting
Recruiting
A Prospective Database of Infants With Cholestasis
Conditions: Biliary Atresia; Neonatal Cholestasis
Conditions: Biliary Atresia; Neonatal Cholestasis
August 6, 2019
41
NCT02068807
Completed
Completed
Evaluation of Antioxidant Activity of Oral Lutein in Preterm and Term Newborn
Conditions: Infant, Newborn, Diseases; Other Lipid Storage Disorders
Intervention: Lutein Drops, Glucose Drops
Conditions: Infant, Newborn, Diseases; Other Lipid Storage Disorders
Intervention: Lutein Drops, Glucose Drops
February 24, 2014
42
NCT01475357
Completed
Completed
Intestinal Function in Neonates With Complex Congenital Heart Disease
Conditions: Congenital Heart Defects; Growth Failure
Intervention: Arm 1: NPO By Mouth Pre-operative, Arm 2: Fresh Breast Milk Pre-operative
Conditions: Congenital Heart Defects; Growth Failure
Intervention: Arm 1: NPO By Mouth Pre-operative, Arm 2: Fresh Breast Milk Pre-operative
October 14, 2014
43
NCT00855361
Completed
Completed
A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in New Born Infants With Gastroesophageal Reflux Disease (GERD)
Conditions: Gastroesophageal Reflux
Intervention: Rabeprazole Sodium
Conditions: Gastroesophageal Reflux
Intervention: Rabeprazole Sodium
April 26, 2013
44
NCT00113464
Completed
Completed
Developing Newborn Screening for Infants With Primary Immunodeficiency
Conditions: Immune System Diseases
Conditions: Immune System Diseases
June 30, 2017
45
NCT02668107
Unknown status
Unknown status
Electromyographic Activity of Preterm Newborns Submitted to Hammock Positioning
Conditions: Infant, Premature, Diseases
Intervention: Hammock Positioning
Conditions: Infant, Premature, Diseases
Intervention: Hammock Positioning
August 15, 2017
46
NCT01062828
Terminated
Terminated
Defining Normal Citrulline Levels as a Diagnostic Tool for Screening of Gastrointestinal Disease in Premature Infants
Conditions: Premature Newborn; Necrotizing Enterocolitis
Intervention: Citrulline Samples
Conditions: Premature Newborn; Necrotizing Enterocolitis
Intervention: Citrulline Samples
August 24, 2017
47
NCT01619657
Completed
Completed
Preventive Inhalation of Hypertonic Saline in Infants With Cystic Fibrosis
Conditions: Cystic Fibrosis Lung Disease
Intervention: 6% Hypertonic Saline (HS), 4mL, 0.9% Isotonic Saline (IS), 4mL
Conditions: Cystic Fibrosis Lung Disease
Intervention: 6% Hypertonic Saline (HS), 4mL, 0.9% Isotonic Saline (IS), 4mL
October 25, 2017
48
NCT01388439
Completed
Completed
Pharmacokinetics of Oseltamivir in Newborns and Infants
Conditions: Prematurity of Fetus
Intervention: Oseltamivir
Conditions: Prematurity of Fetus
Intervention: Oseltamivir
July 5, 2011
49
NCT01439048
Completed
Completed
Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants
Conditions: Premature Birth
Conditions: Premature Birth
August 27, 2015
50
NCT02486263
Active, not recruiting
Active, not recruiting
Neonatal Gastro-Esophageal Reflux Disease (GERD) Management Trial
Conditions: Gastroesophageal Reflux Disease
Intervention: Study
Conditions: Gastroesophageal Reflux Disease
Intervention: Study
April 19, 2019
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Last Updated
The last updated date is the most recent date when changes to a clinical trial were
submitted to ClinicalTrials.gov. There is often a delay of a few days before the
updated trial is available on the clinical trials website.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Specify a From date to find the most recently changed trials. Specify both From and To dates to find trials changed during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
First Received
The first received date is the date when the clinical trial was first submitted
to ClinicalTrials.gov. There is often a delay of a few days before the
trial is available on the clinical trials website.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Safety Issue
If selected, restricts search results to those studies which have
an outcome measure designated as a safety issue. Note that this is a
poor estimate of the safety of a treatment or intervention, but it is
all we have now.
Funded By
Studies are supported by one or more organizations called sponsors.
Support includes contributions of facilities, expertise, and/or financial resources.
All sponsors in the database have been assigned one of the following organization types:
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
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Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
National Institutes of Health (NIH)
Other U.S. Federal Agency - Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDC), Department of Veterans Affairs (VA), etc.
Industry - the pharmaceutical companies
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Click the check box to the left of each organization type that you wish to include in your search. You can select more than one organization type. If you do not select any type, all types will be included.
Study Phase
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Most clinical trials are designated as phase 1, 2, 3, or 4, based on the type of questions
that study is seeking to answer:
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
Click the check box to the left of each study phase that you wish to include in your search. You can select more than one study phase. If you do not select a any phase, all phases will be included.
Age Group
Studies may be designed for participants of particular ages:
Children (birth-17 yrs old)
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Gender
Searches can be restricted to studies which accept female or male participants.
Location Terms
If you are interested in a specific city (such as Los Angeles) or facility
name (such as the Mayo Clinic), enter it as a location term. Not all studies
include this level of detail, but if they do, this will find them.
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Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
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Study IDs
Each trial is assigned one or more identification numbers by the institute, agency,
or organization sponsoring the trial. In addition, clinical trials assigns a
unique NCT identifier of the form NCTxxxxxxxx where each x is a numeric digit.
Use this box to search for a trial by NCT identifier or any other study
identification numbers.
Examples:
Examples:
NCT00001789
97-h-0197
ia0006
actg 076
97-h-0197
ia0006
actg 076
Sponsor (Lead)
Use this box to specify the name of an institute, organization, or company that is
conducting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Sponsor/Collaborators
Use this box to specify institutes, organizations, or companies that are
conducting or otherwise supporting a trial.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Outcome Measures
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Outcome measures are used to evaluate trial results. For example, an obesity treatment
might be evaluated by a measure of weight loss after 6 months. Measures can also be used
to quantify side effects, such as number of myocardial infarctions,
number of patients with heart arrhythmia, number of suicides, etc.
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
suicide
Interventions
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Interventions refer to the drug, vaccine, procedure, device, or other potential treatment being studied.
Interventions can also include less intrusive possibilities such as surveys, education, and interviews.
Use this box to specify drugs, devices, procedures, or vaccines used in a trial.
Examples:
clofibrate
cyclosporine
vitamin e
Conditions
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Conditions usually refer to a disease, disorder, syndrome, illness, or injury. In ClinicalTrials.gov,
conditions include any health issue worth studying, such as lifespan, quality of life, health risks, etc.
Use this box to specify the conditions being studied.
Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
Study Type
There are three types of studies available in ClinicalTrials.gov:
There are three types of studies available in ClinicalTrials.gov:
Interventional:
Observational:
Expanded Access:
Studies where individuals are assigned to receive specific interventions.
Participants may receive diagnostic, therapeutic or other types of interventions.
Assignment of the intervention may or may not be random.
Individuals are tracked and biomedical and/or health outcomes are assessed.
Observational:
Studies without an intervention.
Studies where biomedical and/or health outcomes are assessed in a pre-defined group of individuals.
Participants may receive diagnostic, therapeutic, or other interventions, but the investigator
does not assign specific interventions to the participants of the study.
Expanded Access:
Records describing the procedure for obtaining an experimental drug or device for patients who
are failing on currently available treatments for their condition and also are unable to
participate in ongoing clinical trials. Expanded Access records are used to register all
types of non-protocol access to experimental treatments, including protocol exception,
single-patient IND, treatment IND, compassionate use, emergency use, continued access and parallel track.
Study Results
Searches can be restricted to studies with or without results.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
Recruitment Status
Also known as Enrollment Status.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Not all clinical trials in this database are accepting new participants. If you are looking for studies that are currently recruiting participants, will be recruiting in the future, or are about drugs that are available for expanded access, select Open Studies in the recruitment menu.
If you are interested in all trials, whether they are recruiting new participants or not, leave the menu with All Studies selected.
Trials may not be recruiting because they are full, completed, or halted for various reasons. In addition, some trials have very restrictive eligibility requirements and must seek participants by invitation only. To see these studies, Select Closed Studies in the recruitment menu.
Full list of all possible recruitment status values:
Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Search Terms
Use this box to specify general search terms found anywhere in the trial record.
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help for Searching clinical trials
Help Topics:
Basic Search:
On the Basic Search page, enter a word or word(s) that you want to use to find studies.
These may include diseases, interventions, and/or locations.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
Use of a Pacemaker Following a Heart Attack.
higher than the study,
Heart Defects and Transient Ischemic Attacks
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
Advanced Search:
Many searches are a single term and can be performed with a few words in the
search box. But, sometimes you need more control. Click on the Advanced Search tab
(if starting a new search) or Refine Search tab (if modifying an existing search)
to show additional search fields.
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Recruitment:
Interventions:
Outcomes Measures:
Sponsor/Collaborators:
Sponsor (Lead):
Study IDs:
Country/State:
Location Terms:
Gender:
Age Group:
Phase:
Funded By:
Safety Issue:
First Received:
Last Updated:
The additional search fields can be used to limit your search results. Note that it is not necessary to fill in all the fields, only those that are needed for your search. If you are finding too few studies, consider clearing a field and searching again.
Search Terms:
Performs a general search in all sections of the study record, including title,
description, conditions, interventions, locations, etc. Terms in this field are
searched the same as Basic Search.
Recruitment:
Limits search results to studies that are open or closed. New volunteers may be
able to participate in open studies, but not closed studies.
Open recruitment status values:
Closed recruitment status values:
Values are color coded (as shown) in the search results.
Study Results:Open recruitment status values:
Recruiting,
Not yet recruiting, or
Available for expanded access.
Not yet recruiting, or
Available for expanded access.
Closed recruitment status values:
Active, not recruiting,
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Completed,
Terminated,
Suspended,
Withdrawn,
Enrolling by invitation,
Temporarily not available for expanded access,
No longer available for expanded access,
Approved for marketing, or
Unknown.
Values are color coded (as shown) in the search results.
Limits search results based on whether the study has results or not:
Study Type:
All Studies,
Studies With Results, or
Studies Without Results
The inclusion of Study Results is a new feature of ClinicalTrials.gov.
Only a few studies have results available.Studies With Results, or
Studies Without Results
Limits search results to any of the following study types:
Conditions:
Interventional,
Observational, or
Expanded Access
Observational, or
Expanded Access
Performs a search on fields describing the diseases or conditions being studied.
Interventions:
Performs a search on fields listing the drugs or interventions being studied.
Outcomes Measures:
Performs a search on fields listing the outcome measures used to quantify study results.
Sponsor/Collaborators:
Performs a search on fields listing the sponsor and collaborators of a study.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
Performs a search on the sponsor field of a study.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
Performs a search on fields listing ID numbers.
Country/State:
Trials are often conducted at many locations around the world.
Select up to three locations to find trials conducted in
specific countries. Some countries (currently limited to the
United States, Canada, and Australia), locations can be narrowed
further by selecting a state (e.g., United States, Alabama).
Location Terms:
Finds studies in specific locations such as a city (Los Angeles) or facility (Mayo Clinic).
Not all studies include this level of detail, but if they do, this will find them.
Gender:
Limits search results to those studies that accept female or male participants.
Age Group:
Limits search results to those studies that include at least one of the specified age
ranges. More than one age group can be selected.
Phase:
Limits search results to studies that are labeled with at least one of the specified
phases. More than one Phase can be selected.
Funded By:
Limits search results to studies that have at least one sponsor of the specified types.
More than one sponsor type can be selected.
Safety Issue:
Limits search results to studies that have at least one outcome measure designated as a safety issue.
First Received:
Limits search results to studies that were received by clinical trials within a
specified date range. The "From" or "To" field can be left blank.
Last Updated:
Limits search results to studies that were modified within a
specified date range. The "From" or "To" field can be left blank.
Refine Search:
Searches display a list of studies found (List Results tab). If you are not content with
the search results, click on the Refine Search tab at the top of the list to modify your
search.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
When you are done making changes, click Search to display the new results.
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
Use AND (all upper case) to find study records that contain all terms connected by AND.
For example:
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.
For example:
prostate cancer AND radiation
heart disease AND stroke AND California
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
Aspirin OR ibuprofen
heart disease OR heart attack
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Immunodeficiency NOT AIDS
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
prostate cancer AND NOT ( radiation OR homeopathic remedies )
( heart disease OR heart attack ) AND ( stroke OR clot )
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
Ear, Nose, and Throat Conditions
is the expression
( Ear OR Nose OR Throat ) AND Conditions
Fortunately, search will do a pretty good job of finding the right studies either way.To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.