Clinical Trials: SEARCH[Study] TILT[Study:StudyFirstPostDate] AREA[BasicSearch] Infant Newborn Diseases
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Completed
Conditions: Premature Birth of Newborn; Family; Immature Newborn; Newborn Morbidity; Infant Newborn Disease
Intervention: Parent Navigator, Care Notebook
Terminated
Conditions: Infant; Newborn Diseases
Intervention: Glucose 25%, Glucose 25%
Completed
Conditions: Growth Disorders
Intervention: Intervention Cluster
Completed
Conditions: Heart Disease; Health
Intervention: No Intervention
Recruiting
Conditions: Anesthesia Intubation Complication; Infant; Newborn
Intervention: Group D, Group E
Completed
Conditions: Streptococcus Agalactiae
Intervention: Blood Sample, Vaginal Swab Sample
Withdrawn
Conditions: Invasive Group B Streptococcus Disease
Completed
Conditions: Hydrocephalus; Nervous System Diseases; Infant, Newborn Diseases
Completed
Conditions: Congenital Cardiovascular Malformation
Intervention: Pulse Oximetry Using The INVOS (In Vivo Optical Spectroscopy) Cerebral/Somatic Oximeter
Completed
Conditions: Atopic Dermatitis; Allergic Rhinitis; Asthma
Intervention: Lactobacillus Rhamnosus GG
Recruiting
Conditions: Opioid-use Disorder; Opioid Use, Unspecified; Buprenorphine Dependence
Intervention: Subutex / Buprenorphine, Fetal & Neonatal MRI, DNA/Genetic/Pharmacokenetic Blood Draws
Recruiting
Conditions: Newborn Infants With Enterostomy by Congenital Malformations of the Gastrointestinal Tract, Necrotizing Enterocolitis and Spontaneous Intestinal Perforation
Intervention: Exposure(s) Of Interest: Enterostomy
Withdrawn
Conditions: Herpes Simplex Virus
Intervention: Novel Antiviral Drug, Placebo
Completed
Conditions: Infant, Premature, Diseases
Intervention: Lactobacillus Reuteri (biogai AB, Sweden)
Not yet recruiting
Conditions: Sickle Cell Disease; Infant, Newborn, Disease; Drepanocytosis
Intervention: SCD Newborn Screening With The MS/MS Method From Zentech
Completed
Conditions: Invasive Group B Streptococcus Disease
Recruiting
Conditions: HIV, Neonatal HIV Early-Infant-Diagnosis (EID), Point-of-Care Testing (PoC)
Intervention: Point-of Care (PoC) Neonatal HIV Early Infant Diagnosis (EID)
Not yet recruiting
Conditions: Meconium Aspiration Syndrome; Infant, Newborn, Disease; Neonatal Resuscitation
Intervention: Endotracheal Suctioning, No Endotracheal Suctioning
Completed
Conditions: Congenital Heart Disease
Intervention: EQUANOX Advance 8004CB Sensor
Recruiting
Conditions: Retinopathy of Prematurity (ROP); Intraventricular Hemorrhage; Bronchopulmonary Dysplasia; Chronic Lung Disease of Prematurity
Intervention: SHP607
Enrolling by invitation
Conditions: Spinal Muscular Atrophy; Fragile X Syndrome; Fragile X - Premutation
Intervention: Confirmatory Testing
Completed
Conditions: Gastroesophageal Reflux
Intervention: Pantoprazole
Recruiting
Conditions: Acute Kidney Injury; Chronic Kidney Disease
Recruiting
Conditions: Infant, Newborn, Diseases
Intervention: Measurement Of Sternal-notch To Umbilicus Distance
Active, not recruiting
Conditions: Metabolism, Inborn Errors; Hearing Loss; Hereditary Disease
Intervention: Well Infant, Whole Exome Sequencing, Diagnosed, Whole Exome Sequencing
Recruiting
Conditions: Hyaline Membrane Disease; Preterm Infant
Intervention: Electrocardiogram
Active, not recruiting
Conditions: Hereditary Disease; Genetic Predisposition to Disease
Intervention: Genomic Sequencing, Family History Report
Active, not recruiting
Conditions: Krabbe Disease
Completed
Conditions: Cholestasis in Newborn
Intervention: Cyclic Parenteral Nutrition
Completed
Conditions: Respiratory Syncytial Virus Infection
Intervention: Palivizumab
Not yet recruiting
Completed
Conditions: Infant, Newborn, Diseases; Airway Morbidity
Intervention: Spontaneous Breathing Trial
Completed
Conditions: Term Delivery With Preterm Labor, Third Trimester; Term Delivery With Preterm Labor, Unspecified Trimester; Bronchopulmonary Dysplasia
Intervention: Measurements
Unknown status
Conditions: Infant, Newborn, Diseases
Intervention: Glucose 25%, Materna RTF Stage 1, Water For Injection
Completed
Conditions: Congenital Disorders
Active, not recruiting
Conditions: Heart Defects, Congenital
Completed
Conditions: Infant, Premature, Diseases
Intervention: Enhanced Discharge Process
Completed
Conditions: Infant, Newborn, Diseases; Other Lipid Storage Disorders
Intervention: Lutein Drops, Glucose Drops
Suspended
Conditions: Infant, Premature, Diseases
Intervention: Laser Speckle Imaging And Diffuse Optical Spectroscopy
Unknown status
Conditions: Infant, Newborn, Diseases; Sepsis; Puerperal Infection
Intervention: Chlorhexidine, Birth Canal Wipe, Sterile Water External Genital Wipe
Recruiting
Conditions: Cystic Fibrosis Lung Disease
Recruiting
Conditions: Biliary Atresia; Neonatal Cholestasis
Active, not recruiting
Conditions: Gastroesophageal Reflux Disease
Intervention: Study
Completed
Conditions: Congenital Heart Defects; Growth Failure
Completed
Conditions: Gastroesophageal Reflux
Intervention: Rabeprazole Sodium
Completed
Conditions: Immune System Diseases
Unknown status
Conditions: Infant, Premature, Diseases
Intervention: Hammock Positioning
Terminated
Conditions: Premature Newborn; Necrotizing Enterocolitis
Intervention: Citrulline Samples
Completed
Conditions: Cystic Fibrosis Lung Disease
Intervention: 6% Hypertonic Saline (HS), 4mL, 0.9% Isotonic Saline (IS), 4mL
Unknown status
Conditions: Newborn; Infection
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Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
Clinical trial records are often updated after they have been published. The first received, last updated, start, and end dates are all displayed in the full text view of the clinical trial.
Specify a From date to find the most recent trials. Specify both From and To dates to find trials submitted during a certain period. If no dates are given, all trials will be included.
Dates should be given in a MM/DD/YYYY format, as in 1/1/2006 or 8/17/2004.
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In Phase 1 (Phase I) clinical trials, researchers test a new drug or treatment in a small group of people (20-80) for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
In Phase 2 (Phase II) clinical trials, the study drug or treatment is given to a larger group of people (100-300) to see if it is effective and to further evaluate its safety.
In Phase 3 (Phase III) clinical trials, the study drug or treatment is given to large groups of people (1,000-3,000) to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
In Phase 4 (Phase IV) clinical trials, post marketing studies delineate additional information including the drug's risks, benefits, and optimal use.
These phases are defined by the Food and Drug Administration in the Code of Federal Regulations.
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Examples:
97-h-0197
ia0006
actg 076
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
A search in this area will check only the sponsor field. To also look for collaborators, use the Sponsor/Collaborators search box.
When the Exact Match checkbox is checked, the sponsor name in the study must exactly match the sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the sponsor is decided by the data provider.
Searching this area will look in both the sponsor field and in the collaborators field. To only look in the sponsor field, use the Sponsor (Lead) search box.
When the Exact Match checkbox is checked, the name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Examples:
National Cancer Institute
Mayo Clinic
Bristol-Myers Squibb
Use this box to specify an outcome measure used to evaluate trial results.
Examples:
weight loss
heart failure
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Examples:
clofibrate
cyclosporine
vitamin e
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Examples:
lupus
heart attack
leukemia
risk factors for breast cancer
There are three types of studies available in ClinicalTrials.gov:
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The inclusion of study results is a relatively new feature of ClinicalTrials.gov. Collection of results began in September of 2008. Almost all older studies and some newer studies do not include results. As time goes on, there will be more results available.
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Full list of all possible recruitment status values:
Open recruitment status values:
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Available for expanded access.
Closed recruitment status values:
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Multiple terms can be separated by an AND (all uppercase).
Examples:
type ii diabetes
veterans affairs medical center
heart attacks in older adults
nhlbi AND heart disease
Cisplatin AND safety study
Help Topics:
Basic Search:
Medical terms are often several words long, such as Percutaneous Coronary Intervention. To only find studies where the words are together as a phrase, put the term in quotes (e.g., "Percutaneous Coronary Intervention"). If you search for a multi-word term without quotes, studies with all words together as a phrase will appear higher in the results list than studies where the words are separated and spread throughout the document. For example, a search for Heart Attack will list a study about,
A search for "Heart Attack" would not find the second study. Synonyms are known for some terms and are used where possible. For example, a search for Heart Attack will also find occurrences of Myocardial Infarction.
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Recruitment:
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Values are color coded (as shown) in the search results.
Studies With Results, or
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Interventions:
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Sponsor/Collaborators:
When the Exact Match checkbox is checked, the sponsor/collaborator name in the study must exactly match the name in the search. For example, if unchecked, a search for Merck in the sponsor/collaborator field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Sponsor (Lead):
It is common for several organizations to collaborate by providing funding, facilities, experimental treatments, etc. Which organization is considered the "sponsor" is decided by the data provider.
When the Exact Match checkbox is checked, the lead sponsor name in the study must exactly match the lead sponsor name in the search. For example, if unchecked, a search for Merck in the lead sponsor field will find Merck, Merck KGaA, Dupont Merck, and Merck Sharp & Dohme. When checked, only Merck, with no other words in the name, will be found.
Study IDs:
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Location Terms:
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Age Group:
Phase:
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Safety Issue:
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Refine Search:
Add terms to empty fields to search within your current result. You can also add terms to fields that contain terms. For best results, use an AND (all upper case) as a separator between terms in the same field.
For example:
heart attack AND aspirin
heart attack AND aspirin AND older adults
heart attack AND aspirin AND older adults AND California
When you are done making changes, click Search to display the new results.
Search Expressions:
For example:
heart disease AND stroke AND California
Use OR (all upper case) to find study records that contain either term connected by OR.
For example:
heart disease OR heart attack
Use NOT (all upper case) to find study records that do not contain the term following NOT.
For example:
Likewise, AND, OR, NOT, and parentheses can be used to create more complicated search expressions.
For example:
( heart disease OR heart attack ) AND ( stroke OR clot )
Note that the use of AND and OR as logical operators can be confusing.
An appropriate search for a list such as,
To search for AND as a word, instead of using it as an operator, put it in quotes.
Likewise, you can quote OR, NOT, and parentheses.