Clinical Trials on Acute Monoblastic Leukemia

Total 18559 results

Stanford University
Genzyme, a Sanofi Company

Terminated

Allogeneic HCT Using Nonmyeloablative Host Conditioning With TLI & ATG vs SOC in AML

Leukemia | Leukemia, Myeloid | Acute Myeloid Leukemia (AML)

United States
Weill Medical College of Cornell University

Terminated

Pacritinib Combined With Decitabine or Cytarabine in Older Patients With AML (Pacritinib)

Acute Myeloid Leukemia (AML)

United States
Institute of Hematology & Blood Diseases Hospital

Completed

Efficacy Analysis of Comparison of CAMS（Chinese Academy of Medical Sciences）-2005 Trial and CAMS-2009 Trial for Pediatric Acute Myeloid Leukemia

Acute Myeloid Leukemia, Pediatric

China
Chunyan Ji
Qingdao University; Qianfoshan Hospital; Jinan Central Hospital; Jining Medical... and other collaborators

Unknown

Decitabine in Combination With Low-dose Cytarabine in Elderly Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia, Adult
Sanofi

Terminated

Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia (ISLAY)

T-cell Type Acute Leukemia-Precursor | T-lymphoblastic Lymphoma/Leukaemia

Hungary, United States, Finland, France, Italy, Lithuania, Russian Federation
The University of Hong Kong

Recruiting

The Acute Promyelocytic Leukaemia Asian Consortium (APL-AC) Project

Acute Promyelocytic Leukemia

Hong Kong
The University of Hong Kong

Recruiting

Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia

Acute Promyelocytic Leukemia

Hong Kong
First Affiliated Hospital Xi'an Jiaotong University
Tang-Du Hospital

Recruiting

Treatment of Non-high-risk Acute Promyelocytic Leukemia (APL) With Realgar-Indigo Naturalis Formula (RIF) (APL16)

Acute Promyelocytic Leukemia

China
Technische Universität Dresden
German Federal Ministry of Education and Research; Groupe Francophone des Myelodysplasies and other collaborators

Active, not recruiting

Study for Patients With Newly Diagnosed, High-risk Acute Promyelocytic Leukemia (TUD-APOLLO-064)

Acute Promyelocytic Leukemia

France, Germany, Italy, Netherlands, Spain
Shanghai Jiao Tong University School of Medicine
The First Affiliated Hospital with Nanjing Medical University; The First Affiliated... and other collaborators

Unknown

Combined Retinoic Acid,Arsenic Trioxide and Chemo for Newly-diagnosed APL

Acute Promyelocytic Leukemia

China
M.D. Anderson Cancer Center

Completed

All-trans Retinoic Acid, and Arsenic +/- Idarubicin

Acute Promyelocytic Leukemia

United States
Northwestern University
CytRx; Cephalon

Terminated

Tamibarotene and Arsenic Trioxide for Relapsed Acute Promyelocytic Leukemia

Acute Promyelocytic Leukemia

United States
PETHEMA Foundation

Completed

Treatment of Acute Promyelocytic Leukemia With All-Trans Retinoic Acid (ATRA) and Idarubicin (AIDA)

Acute Promyelocytic Leukemia

Spain
M.D. Anderson Cancer Center

Active, not recruiting

Venetoclax in Combination With Decitabine and Cedazuridine for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Recurrent Acute Biphenotypic Leukemia | Refractory Acute Biphenotypic Leukemia

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Completed

S1312, Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Acute Leukemia

Recurrent Adult Burkitt Lymphoma | Recurrent Adult Acute Lymphoblastic Leukemia | B-cell Adult Acute Lymphoblastic Leukemia | Acute Leukemias of Ambiguous Lineage | Philadelphia Chromosome Positive Adult Precursor Acute Lymphoblastic Leukemia

United States
Institute of Hematology & Blood Diseases Hospital
Bejing Institute for Stem Cell and Regenerative Medicine; Institute for Stem...

Recruiting

Safety and Preliminary Efficacy of JK500 Cell Injection in Relapsed/Refractory Pediatric Acute Myeloid Leukemia

Refractory Leukemia | Relapsed Leukemia | Acute Myeloid Leukemia, Childhood

China
University of California, Irvine
Pfizer; Jazz Pharmaceuticals

Recruiting

CPX-351 and Glasdegib for Newly Diagnosed Acute Myelogenous Leukemia With MDS Related Changes or Therapy-related Acute Myeloid Leukemia

Acute Myeloid Leukemia With Myelodysplasia-Related Changes | Acute Myelogenous Leukemia (AML) Due to Therapy

United States
Therapeutic Advances in Childhood Leukemia Consortium
Ambit Biosciences Corporation

Completed

AC220 for Children With Relapsed/Refractory ALL or AML

Lymphoblastic Leukemia, Acute, Childhood | Myelogenous Leukemia, Acute, Childhood

United States
Therapeutic Advances in Childhood Leukemia Consortium
Gateway for Cancer Research

Completed

A Phase I Study of 5-Azacytidine in Combination With Chemotherapy for Children With Relapsed or Refractory ALL or AML

Lymphoblastic Leukemia, Acute, Childhood | Myelogenous Leukemia, Acute, Childhood

United States, Canada, Australia
University Hospital, Bordeaux

Recruiting

Impact of Optical Genome Mapping in Acute Myeloblastic Leukemia (COALA)

Acute Myeloblastic Leukemia

France
Igenica Biotherapeutics, Inc.

Completed

A Phase I Study of IGN523 in Subjects With Relapsed or Refractory AML

Acute Myeloid Leukemia | Acute Myelogenous Leukemia

United States
Acute Leukemia French Association
Assistance Publique - Hôpitaux de Paris

Withdrawn

ALFA-0703 Study in Older Patients With Acute Myeloblastic Leukemia (AML) (ALFA-0703)

Acute Myeloid Leukemia

France
Technische Universität Dresden

Completed

AML96 - Risk-Adapted and Randomized Postremission-Therapy for Adult Acute Myeloid Leukemia Patients

Leukemia, Nonlymphoblastic, Acute

Germany
Second Affiliated Hospital of Xi'an Jiaotong University
Nanjing Legend Biotech Co.

Terminated

Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute Leukemia

Acute Myeloid Leukemia | Acute Leukemia | Acute Leukemia in Relapse | Relapsed or Refractory Acute Leukemia

China
Memorial Sloan Kettering Cancer Center
Astellas Pharma US, Inc.

Recruiting

A Study of Gilteritinib in Combination With Ivosidenib or Enasidenib in People With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML)

United States
Grupo Argentino de Tratamiento de la Leucemia Aguda

Recruiting

RWE of 1st Line Treatment in Adults With AML From 18 to 70 Years Old.

Acute Myeloid Leukemia, Adult

Argentina
Acute Leukemia French Association

Recruiting

Prospective Non-interventional Study of Adult Patients With Acute Myeloid Leukemia (AML) (ALFAPPP)

Acute Myeloid Leukemia (AML)

France
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Recruiting

A Study of SKLB1028 Versus Salvage Chemotherapy in Patients With Relapsed or Refractory (R/R) AML With FLT3-Mutated (ALIVE)

Acute Myeloid Leukemia (AML)

China
AbbVie
Roche-Genentech

Active, not recruiting

A Study of Oral Venetoclax Tablets and Oral Azacitidine Versus Oral Azacitidine as Maintenance Therapy in Adult Participants With Acute Myeloid Leukemia in First Remission After Conventional Chemotherapy (VIALE-M)

Acute Myeloid Leukemia (AML)

United States, Australia, Canada, China, Czechia, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Puerto Rico, Russian Federation, Spain, Taiwan, Turkey, United Kingdom
AbbVie
Genentech, Inc.

Active, not recruiting

A Study of Venetoclax in Combination With Azacitidine Versus Azacitidine in Treatment Naïve Participants With Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy (Viale-a)

Acute Myeloid Leukemia (AML)

United States, Australia, Austria, Belgium, Brazil, Canada, China, Croatia, Czechia, Denmark, Finland, France, Germany, Hungary, Israel, Italy, Japan, Korea, Republic of, Norway, Poland, Portugal, Puerto Rico, Russian Federation, South... and more
Nantes University Hospital

Completed

Monocentric Phase 1 Study With Escalation of Doses of Tocilizumab in Combination With Chemotherapy (Idarubicin and Cytarabine) in Patients With Acute Myeloblastic Leukemia (AML) (Tocilam)

Acute Myeloid Leukemia (AML)

France
Dana-Farber Cancer Institute
National Institute of Nursing Research (NINR)

Completed

Feasibility Pilot Exploring Variability in Biomarkers and PROs in AML

Acute Myeloid Leukemia (AML)

United States
Gruppo Italiano Trapianto di Midollo Osseo

Completed

Busulfan (BU) Plus Fludarabine Vs Intravenous BU Plus Cyclophosphamide as Conditioning Regimens Prior Allogeneic Hematopoetic Stem Cells Transplant (HSCT) in AML (GITMO-AMLR2)

Acute Myeloid Leukemia (AML)

Italy, Israel
Karyopharm Therapeutics Inc

Completed

Selinexor (KPT-330) in Older Patients With Relapsed AML (SOPRA)

Acute Myeloid Leukemia (AML)

Canada, United States, Israel, Netherlands, Denmark, Spain, France, Italy, United Kingdom, Germany, Poland
AbbVie
Merck Sharp & Dohme LLC

Terminated

A Study of Venetoclax and Dinaciclib (MK7965) in Patients With Relapsed/Refractory Acute Myeloid Leukemia

Cancer - Acute Myeloid Leukemia

United States, Australia, Spain
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia

Relapsed Acute Myeloid Leukemia

United States
Novartis Pharmaceuticals

Completed

Healthcare Resource Utilization in Adults Diagnosed With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML)

Finland
Association for Training, Education, and Research...

Completed

Sequential Conditioning in Haploidentical Transplantation for Refractory Acute Myeloid Leukemia (SET-HAPLO)

Refractory Acute Myeloid Leukemia

France
AbbVie

Completed

A Study of Oral Venetoclax Tablet in Combination With Subcutaneous Low-Dose Cytarabine (LDAC) Injection to Assess Adverse Events in Adult Japanese Participants With Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia (AML)

Japan
Wake Forest University Health Sciences

Terminated

Leukemia Stem Cell Detection in Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

United States
Hoffmann-La Roche

Terminated

A Study of Idasanutlin With Cytarabine Versus Cytarabine Plus Placebo in Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML) (MIRROS)

Leukemia, Myeloid, Acute

Italy, Korea, Republic of, Belgium, Australia, United States, Canada, United Kingdom, Spain, Netherlands, France, Germany, New Zealand, Israel, Norway, Russian Federation, Switzerland, Austria, Finland, Panama
AbbVie
Astellas Pharma Inc; Genentech, Inc.

Completed

A Study to Assess Safety and Efficacy of Venetoclax in Combination With Gilteritinib in Participants With Relapsed/Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

United States
Golden Biotechnology Corporation

Completed

Evaluate Efficacy and Safety/Tolerability Profiles of Antroquinonol in Acute Myeloid Leukemia (AML) Adult Patients

Leukemia, Myeloid, Acute

Russian Federation
Bayer

Completed

BAY1436032 in Patients With Mutant IDH1(mIDH1) Advanced Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute

United States, Germany
Michael Boyiadzis
Merck Sharp & Dohme LLC

Withdrawn

Phase 0- Pilot Study of Pembrolizumab on Immune Cells in Patient With Refractory Acute Myeloid Leukemia

Refractory Acute Myeloid Leukemia

United States
Fondazione Policlinico Universitario Agostino Gemelli...
Associazione Italiana per la Ricerca sul Cancro

Unknown

Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75

Acute Myeloid Leukemia, Adult

Italy
Astellas Pharma Inc

Completed

Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of ASP2215 in Japanese Patients With Relapsed or Refractory Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML)

Japan
University of Ulm
German Federal Ministry of Education and Research

Completed

Study of Low-Dose Cytarabine and Etoposide With or Without All-Trans Retinoic Acid in Older Patients Not Eligible for Intensive Chemotherapy With Acute Myeloid Leukemia and NPM1 Mutation

Acute Myeloid Leukemia (AML)

Germany
Assiut University

Unknown

Cd11b and Cd56 as Prognostic Markers in Acute Myeloid Leukemia

Adult Acute Myeloid Leukemia
Sanofi

Withdrawn

Open Label Study of Sargramostim Among Patients Receiving Myelosuppressive Induction Chemotherapy for Acute Myelogenous Leukemia

Acute Myeloid Leukemia NOS

Clinical Trials on Acute Monoblastic Leukemia

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