Clinical Trials on Advanced Gastric and Gastro-esophageal Junction Adenocarcinoma

Total 3558 results

AstraZeneca

Completed

PPI Sequencing Study

Gastro-Oesophageal Reflux Disease

United Kingdom
Ashwin Somasundaram
EMD Serono; University of North Carolina, Chapel Hill

Completed

Trial of mFOLFOX6 + Trastuzumab + Avelumab in Gastric and Esophageal Adenocarcinomas

Gastric Adenocarcinoma | Metastasis | Esophageal Adenocarcinoma | HER-2 Gene Amplification

United States
West China Hospital
Beijing YouAn Hospital; Guangzhou First People's Hospital; Renmin Hospital of... and other collaborators

Not yet recruiting

Preemptive TIPS for Gastric Variceal Bleeding in Patients With Cirrhosis

Portal Hypertension | Portosystemic Shunt | Gastric Varices Bleeding
Air Force Military Medical University, China

Unknown

Interventional Devascularization Plus HVPG-Guided Carvedilol Therapy vs TIPS

Liver Cirrhoses | Gastric Varices Bleeding
Chinese University of Hong Kong

Recruiting

Effect of Routine Anterior Crural Repair in De-Novo Gastroesophageal Reflux After Laparoscopic Sleeve Gastrectomy

Obesity | Gastro Esophageal Reflux Disease

China
Institut d'Investigacions Biomèdiques August Pi...
Hospital Clinic of Barcelona; Germans Trias i Pujol Hospital; Hospital Universitario... and other collaborators

Unknown

TIPS in Fundal Variceal Bleeding (the TFB Study) (TFB)

Bleeding Gastric Varices | Portal Hypertension

Spain
St. James's Hospital, Ireland

Unknown

Classification of Adenocarcinoma of the Esophagogastric Junction

Barrett Esophagus | Siewert Type II Adenocarcinoma of Esophagogastric Junction | Oesophagus Cancer | Siewert Type I Adenocarcinoma of Esophagogastric Junction | Siewert Type III Adenocarcinoma of Esophagogastric Junction

Ireland
Stanford University

Terminated

Assessment of a Serious Illness Conversation Guide (SICG) in Advanced Gastro-Intestinal Cancers

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Neuroendocrine Tumors | Cholangiocarcinoma | Gastrointestinal Cancer | GIST, Malignant

United States
Asian Institute of Gastroenterology, India

Recruiting

EUS Guided Coil Embolization for Primary Prophylaxis of Gastric Varices (EUS)

Gastric Varices Bleeding

India
Indiana University

Completed

Impact of EUS Guided Treatment of Gastric Varices

Gastric Varices Bleeding

United States
Fundacion Miguel Servet

Unknown

Pressure and Flow Study Before and After Treatments for EMD. The pFlow Study (pFlow)

Esophageal Motility Disorders | Gastro-esophageal Reflux

Spain
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

Recurrent Esophageal Carcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Stage IV Esophageal Cancer AJCC v7 | Metastatic Esophageal Squamous Cell Carcinoma | Metastatic Esophageal Adenocarcinoma | Recurrent Gastroesophageal Junction Adenocarcinoma | Recurrent Esophageal Adenocarcinoma and other conditions

United States
Shen Lin

Recruiting

Prospectively Predict the Efficacy of Treatment of Gastrointestinal Tumors Based on Peripheral Multi-omics Liquid Biopsy

Immunotherapy | Advanced Gastric Adenocarcinoma

China
University of Southern California
National Cancer Institute (NCI); New York University

Completed

Study of 5-Fluorouracil and Leucovorin and Intra-abdominal Floxuridine Chemoradiation in Patients With Fully Resected Locally Advanced Gastric Adenocarcinoma

Gastric Cancer | Gastric Adenocarcinoma

United States
Unity Health Toronto

Withdrawn

Primary Prevention of Gastric Varices Bleed

Endoscopic Ultrasound | Gastric Varices Bleeding
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Camrelizumab Combined With Chemotherapy and Radiotherapy Perioperative Treatment of Esophageal Gastric Junction Adenocarcinoma

Gastroesophageal Junction Adenocarcinoma (Siewert II-III)

China
Kaohsiung Veterans General Hospital.

Recruiting

Balloon-occluded Retrograde Transvenous Obliteration for Gastric Variceal Rebleeding

Liver Decompensation | Gastric Varices Bleeding

Taiwan
Tianjin Medical University Cancer Institute and...

Recruiting

Continuation of Serplulimab Plus Chemotherapy After First Progression in Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma: an Open-label, Randomised Phase II Trial

Gastric Cancer (GC) Gastroesophageal Junction Cancer (GEJ)

China
Johannes Gutenberg University Mainz
Pfizer

Completed

Efficacy and Safety of Sunitinib in Metastatic Gastric Cancer

Gastric Adenocarcinoma | Barrett Esophagus

Germany
Peking University Cancer Hospital & Institute

Recruiting

Clinical Study of Pabolizumab for Neoadjuvant Immunotherapy of Locally Advanced Microsatellite-unstable Gastric Adenocarcinoma

Gastric Cancer | Gastric Adenocarcinoma

China
Federation Francophone de Cancerologie Digestive
AstraZeneca

Active, not recruiting

Clinical Trial Evaluating FOLFIRI + Durvalumab vs FOLFIRI + Durvalumab and Tremelimumab in Second-line Treatment of Patients With Advanced Gastric or Gastro-oesophageal Junction Adenocarcinoma

Gastric Cancer | Gastric Adenocarcinoma

France
West China Hospital

Unknown

Acute Gastric Variceal Bleeding: Endoscopic Treatment Versus BRTO

Gastric Varices

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Taladegib, Paclitaxel, Carboplatin, and Radiation Therapy in Treating Patients With Localized Esophageal or Gastroesophageal Junction Cancer

Gastroesophageal Junction Adenocarcinoma | Stage IB Esophageal Adenocarcinoma AJCC v7 | Stage II Esophageal Adenocarcinoma AJCC v7 | Stage IIA Esophageal Adenocarcinoma AJCC v7 | Stage IIB Esophageal Adenocarcinoma AJCC v7 | Stage IIIA Esophageal Adenocarcinoma AJCC v7 | Stage IIIB Esophageal...

United States
West China Hospital

Recruiting

The Use of Propranolol for the Prevention of Worsening of Esophageal Varices in Patients With Isolated Gastric Varices

Portal Hypertension | Liver Cirrhoses | Gastric Varix

China
West China Hospital

Completed

Secondary Prophylaxis of Gastric Variceal Bleed

Gastric Varices

China
Bambino Gesù Hospital and Research Institute
Nestlé Health Science Spain

Not yet recruiting

Health, Economic Analysis and Clinical Aspects of Patients With Neurological Disabilities in Enteral Nutrition With Dedicated Formula. The Role of Nissen's Fundoplication in the Management of Gastroesophageal Reflux

Gastro-Esophageal Reflux | Fundoplication

Italy
Manchester University NHS Foundation Trust

Completed

A Validation Study of the Dx-pH Probe in Children for the Detection of Extra-oesophageal Reflux

Gastro-oesophageal Reflux

United Kingdom
Obafemi Awolowo University Teaching Hospital

Completed

Relationship of Obesity With GERD Among Nigerians

Gastro-esophageal Reflux Disease With Ulceration.
Centre Hospitalier Departemental Vendee

Recruiting

Evaluation of Omentopexy on Gastro-oesophageal Reflux Following Sleeve Gastrectomy (Sleevepexie)

Obesity

France
Henan Cancer Hospital

Recruiting

Camrelizumab Combined With Apatinib for Advanced Gastric or Esophagogastric Adenocarcinoma

Advanced Gastric Carcinoma

China
Peking University
Taiho Pharmaceutical Co., Ltd.

Unknown

Phase III Study to Compare Perioperative Chemotherapy of Oxaliplatin Combined With S-1(SOX) Versus SOX or Oxaliplatin With Capecitabine (XELOX) as Post-operative Chemotherapy in Locally Advanced Gastric Adenocarcinoma With D2 Dissection

Advanced Gastric Carcinoma

China
Instituto Ecuatoriano de Enfermedades Digestivas

Unknown

EUS-guided Combined Therapy Versus Beta Blocker Therapy in Primary Prophylaxis o GOV II and IGV I

Cirrhosis | GastroIntestinal Bleeding | Gastric Varix

Ecuador
Dr. Gordon Buduhan
University of Toronto; London Health Sciences Centre; CancerCare Manitoba

Recruiting

Preoperative Chemotherapy vs. Chemoradiation in Esophageal / GEJ Adenocarcinoma (POWERRANGER)

Esophageal Cancer | Adenocarcinoma, Esophageal | Adenocarcinoma, Gastroesophageal Junction

Canada
Universidade de Passo Fundo

Completed

Spirulina Platensis for PPI Withdrawal (SpAReDPPI)

Dyspepsia | Gastro Esophageal Reflux Disease | Rebound Acid Hypersecretion
Xijing Hospital of Digestive Diseases
First Affiliated Hospital Xi'an Jiaotong University; Henan Provincial People... and other collaborators

Recruiting

Comparison of Different Operations for Siewert Type II Adenocarcinoma of Esophagogastric Junction

Siewert Type II Adenocarcinoma of Esophagogastric Junction

China
Taipei Veterans General Hospital, Taiwan

Recruiting

Antibiotic Prophylaxis in Patients Undergoing GVO (ABX-GV)

Sepsis | Fever | Liver Cirrhoses | Gastric Varix

Taiwan
Precirix

Terminated

A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer

Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment

United States, Canada
The Affiliated Nanjing Drum Tower Hospital of Nanjing...

Not yet recruiting

A Study of Creatine Combined With Curcumin in the Intervention of Early Cachexia in Upper Gastrointestinal Tumors

Stage IV Gastric Cancer | Stage IV Esophageal Cancer | Stage IIIA Gastric Cancer | Stage IIIB Gastric Cancer | Stage III Esophageal Cancer
Zhejiang Cancer Hospital

Recruiting

Tirelizumab in Combination With Chemoradiation in Patients With Unresectable Gastric Cancer or Gastroesophageal Junction Adenocarcinoma

Locally Advanced Gastric Cancer

China
H. Lee Moffitt Cancer Center and Research Institute
AstraZeneca

Completed

Cisplatin and Irinotecan Chemotherapy, Followed by ZD 1839 (Iressa) in Patients With Esophageal or Gastric Carcinomas

Gastric Cancer | Esophageal Cancer

United States, Puerto Rico
Baxter Healthcare Corporation

Completed

Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices

Esophageal and/or Gastric Varices

Germany
Region Skane

Completed

Paracetamol Absorption Technique as a Method for Measuring Gastric Tube Outlet

Esophagectomy | Esophageal and/or Cardia Cancer | Gastric Pull-up Reconstruction

Sweden
Krankenhaus Nordwest
Deutsche Krebshilfe e.V., Bonn (Germany)

Recruiting

HIPEC + FLOT vs. FLOT Alone in Patients With Gastric Cancer and GEJ (PREVENT) (PREVENT)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Germany
Institut für Klinische Krebsforschung IKF GmbH...
Roche Pharma AG

Recruiting

Study of Atezolizumab + FLOT vs. FLOT Alone in Patients With GC/GEJ and High Immune Responsiveness (DANTE)

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

Germany, Switzerland
Hoffmann-La Roche

Active, not recruiting

A Study of Atezolizumab and Trastuzumab in Combination With Capecitabine and Oxaliplatin in Patients With HER2 Positive Locally Advanced Resectable Gastric Cancer of Adenocarcinoma of Gastroesophageal Junction

Gastric Cancer | Gastroesophageal Junction Adenocarcinoma

China
Nanfang Hospital, Southern Medical University

Completed

JNT Versus TNT to Guided OGT-overlap Oesophagojejunostomy

Gastric/Gastroesophageal Junction (g/Gej) Cancer

China
Shanghai Zhongshan Hospital

Unknown

Efficacy and Safety of Anlotinib Hydrochloride Combined With Nivolumab in the Treatment of Gastric and Esophageal Cancer (OASIS)

Gastric Adenocarcinoma | Esophageal Squamous Cell Carcinoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

CD8+ T Cell Therapy and Pembrolizumab in Treating Patients With Metastatic Gastrointestinal Tumors

Metastatic Pancreatic Adenocarcinoma | Stage IV Pancreatic Cancer AJCC v6 and v7 | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Cholangiocarcinoma | Metastatic... and other conditions

United States
Qilu Hospital of Shandong University

Enrolling by invitation

Effect of Re-education on Rebleeding Rate After Endoscopic Treatment in Liver Cirrhosis

Liver Cirrhosis | Bleeding | Gastric Variceal Bleeding | Esophageal Varices Bleeding

China
Instituto Ecuatoriano de Enfermedades Digestivas

Completed

Angiography for Evaluation of the Feeder Vessel in EUS-guided Coils and Cyanoacrylate Therapy for Gastric Varices

Gastric Varices

Ecuador

Clinical Trials on Advanced Gastric and Gastro-esophageal Junction Adenocarcinoma

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