Relationship of Obesity With GERD Among Nigerians

August 30, 2016 updated by: Olusegun Adekanle, Obafemi Awolowo University Teaching Hospital

Relationship Between Body Mass Index, Waist Circumference, Waist Hip Ratio and Erosive Gastroesophageal Reflux Disease in a Tertiary Centre in Nigeria: a Case Control Study

Obesity is a strong risk factor for GERD. This study assessed the role of obesity among patients having erosive GERD and controls.

Study Overview

Status

Completed

Conditions

Intervention / Treatment

Detailed Description

A case control study of patients with erosive GERD. Patients with erosive GERD who had upper gastro-intestinal endoscopy were graded using the Los Angeles classification. Patients and controls had measurements of body mass index (BMI), WC (waist circumference), Waist hip ratio (WHR), and hip circumference (HC). Bio-data was collected from both groups and data were analysed using descriptive and inferential statistics. A p value of equal to or less than 0.05 was considered significant.

Study Type

Observational

Enrollment (Actual)

160

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Eligibility Criteria

Ages Eligible for Study

18 years and older (Adult, Older Adult)

Accepts Healthy Volunteers

No

Genders Eligible for Study

All

Sampling Method

Non-Probability Sample

Study Population

Nigerians with dyspeptic symptoms

Description

Inclusion Criteria:

  • Patients with dyspepsia

Exclusion Criteria:

  • Patients that refused consent.
  • Patients with gastric cancer
  • Patients with gastric outlet obstruction
  • Pregnant women
  • Active gastrointestinal bleeding
  • Cigarette smokers
  • Patients on Naso-gastric tube.

Study Plan

This section provides details of the study plan, including how the study is designed and what the study is measuring.

How is the study designed?

Design Details

  • Observational Models: Case-Control
  • Time Perspectives: Prospective

Cohorts and Interventions

Group / Cohort
Intervention / Treatment
Erosive GERD
Gastroscopy examination.
Other: Gastroscopy
Upper gastrointestinal endoscopy procedure
Control population
Gastroscopy examination.
Other: Gastroscopy
Upper gastrointestinal endoscopy procedure

What is the study measuring?

Primary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Obesity associated with GERD
Time Frame: Immediate.
Measurement of anthropometric indices
Immediate.

Secondary Outcome Measures

Outcome Measure
Measure Description
Time Frame
Body mass index is associated with GERD
Time Frame: Immediate
Measurement of body mass index (kilogram per meter squared)
Immediate
Waist circumference is associated with GERD
Time Frame: Immediate
Measurement of waist circumference (centimeter)
Immediate
Waist hip ratio is associated with GERD
Time Frame: Immediate
Measurement of waist hip ratio
Immediate

Collaborators and Investigators

This is where you will find people and organizations involved with this study.

Sponsor

Obafemi Awolowo University Teaching Hospital

Study record dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Major Dates

Study Start

March 1, 2013

Primary Completion (Actual)

December 1, 2015

Study Completion (Actual)

December 1, 2015

Study Registration Dates

First Submitted

August 12, 2016

First Submitted That Met QC Criteria

August 30, 2016

First Posted (Estimate)

September 5, 2016

Study Record Updates

Last Update Posted (Estimate)

September 5, 2016

Last Update Submitted That Met QC Criteria

August 30, 2016

Last Verified

August 1, 2016

More Information

Terms related to this study

Keywords

Additional Relevant MeSH Terms

Other Study ID Numbers

  • ERC/2009/03/07

Plan for Individual participant data (IPD)

Plan to Share Individual Participant Data (IPD)?

No

This information was retrieved directly from the website clinicaltrials.gov without any changes. If you have any requests to change, remove or update your study details, please contact register@clinicaltrials.gov. As soon as a change is implemented on clinicaltrials.gov, this will be updated automatically on our website as well.

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