Clinical Trials on Advanced Solid Tumors in United Kingdom

Total 11342 results

National Cancer Institute (NCI)

Suspended

Biospecimen Collection in Identifying Genetic Changes in Patients With Breast, Prostate, Colorectal, Liver, or Kidney Cancer or Multiple Myeloma Undergoing Surgery

Malignant Solid Neoplasm | Multiple Myeloma | Breast Carcinoma | Colon Carcinoma | Kidney Carcinoma | Prostate Carcinoma | Liver Carcinoma | Invasive Carcinoma

United States
Pfizer

Completed

A Study Of PF-05082566 As A Single Agent And In Combination With Rituximab

Lymphoma, Follicular | Lymphoma, Large B-Cell, Diffuse | Lymphoma, Non-Hodgkin | Carcinoma, Renal Cell | Carcinoma, Non-Small-Cell Lung | Malignant Melanoma | Carcinoma, Squamous Cell of Head and Neck

United States, Australia, Japan, France, Italy
Dana-Farber Cancer Institute

Recruiting

InAdvance: Surveillance, Prevention, and Interception in a Population at Risk for Cancer

Lung Cancer | Cirrhosis | Barrett Esophagus | Hematologic Malignancy | Non-Alcoholic Fatty Liver Disease | Cancer Risk | Vulvar Intraepithelial Neoplasia | Childhood Cancer Survivors | Lung; Node | Non Alcoholic Steatohepatitis | Osteochondroma | Cancer Predisposition Syndrome | Hereditary Cancer Prediction | Adult... and other conditions

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of Tazemetostat to the Immunotherapy Drug, Pembrolizumab (MK-3475), in Advanced Urothelial Carcinoma

Metastatic Urothelial Carcinoma | Stage III Bladder Cancer AJCC v8 | Stage IV Bladder Cancer AJCC v8 | Locally Advanced Urothelial Carcinoma

United States, Canada
Southwest Oncology Group
National Cancer Institute (NCI)

Completed

S0001 RT and Carmustine With or Without O6BG in Patients With New Glioblastoma Multiforme or Gliosarcoma

Malignant Neoplasms of Eye, Brain and Other Parts of Central Nervous System

United States
Catherine Bollard

Active, not recruiting

Cytotoxic T Cells to Treat Relapsed EBV-positive Lymphoma (ALCI2)

Hodgkin Disease | Non Hodgkin Lymphoma | Leiomyosarcoma | Lymphoepithelioma | Severe Chronic Active EBV Infection Syndrome (SCAEBV)

United States
Verrica Pharmaceuticals Inc.
BioClinica, Inc.; Paidion Research, Inc.; Instat Consulting, Inc.

Completed

A Placebo-Controlled Study Using VP-102 in the Treatment of External Genital Warts (CARE-1)

Skin Diseases | Sexually Transmitted Diseases, Viral | Sexually Transmitted Diseases | Skin Diseases, Infectious | Warts | Papillomavirus Infections | Skin Diseases, Viral | Condylomata Acuminata

United States
ModernaTX, Inc.

Active, not recruiting

A Study of an Epstein-Barr Virus (EBV) Candidate Vaccine, mRNA-1189, in 12- to 30-Year-Old Healthy Adolescents and Adults

Epstein-Barr Virus Infection

United States
University of Washington
Patient-Centered Outcomes Research Institute

Completed

Improving Communication About Serious Illness (ICSI)

End Stage Liver Disease | Heart Failure | Critical Illness | Lung Neoplasms | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Kidney Failure, Chronic | Communication | Chronic Disease | Palliative Care | Advance Care Planning | Terminal Care

United States
Children's Hospital Medical Center, Cincinnati

Unknown

Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

Tufted Angioma | Microcystic Lymphatic Malformation | Kaposiform Hemangioendotheliomas | Capillary Venous Lymphatic Malformation | Venous Lymphatic Malformation | Mucocutaneous Lymphangiomatosis and Thrombocytopenia | Capillary Lymphatic Arterial Venous Malformations | PTEN Overgrowth Syndrome With... and other conditions

United States
Methodist Health System

Enrolling by invitation

Renal Autotransplantation; Case Series

Renal Tumor | Loin Pain-Hematuria Syndrome | Renal Vascular Disease | Nutcracker Syndrome, Renal | Pelvic Trauma | Congestion, Venous

United States
Barbara Ann Karmanos Cancer Institute

Completed

Anti-CD3 x Anti-Erbitux® Armed Activated T Cells (Phase Ib) for Gastrointestinal (GI Cancer)

Colorectal Cancer | Pancreatic Cancer | Colon Carcinoma | Cancer of Pancreas | Pancreatic Neoplasm | Malignant Neoplasm of Large Intestine | Cancer of Colon | Malignant Tumor of Colon

United States
Precigen, Inc
National Cancer Institute (NCI)

Active, not recruiting

Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis

Papillomavirus Infections | Recurrent Respiratory Papillomatosis | Papillomaviridae

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Peripheral Blood Lymphocyte Therapy to Prevent Lymphoproliferative Disorders Caused by Epstein-Barr Virus in Patients Who Have Undergone Transplantation

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm

United States
National Cancer Institute (NCI)

Completed

Cediranib Maleate and Cilengitide in Treating Patients With Progressive or Recurrent Glioblastoma

Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Recurrent Adult Brain Neoplasm

United States
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers

Intraocular Retinoblastoma | Recurrent Retinoblastoma | Extraocular Retinoblastoma

United States, Canada, Puerto Rico
National Cancer Institute (NCI)

Completed

Veliparib, Radiation Therapy, and Temozolomide in Treating Younger Patients With Newly Diagnosed Diffuse Pontine Gliomas

Glioblastoma | Gliosarcoma | Anaplastic Astrocytoma | Untreated Childhood Brain Stem Glioma | Giant Cell Glioblastoma | Untreated Childhood Anaplastic Astrocytoma | Untreated Childhood Giant Cell Glioblastoma | Untreated Childhood Glioblastoma | Untreated Childhood Gliosarcoma | Brain Stem Glioma | Untreated... and other conditions

United States
Dana-Farber Cancer Institute

Recruiting

Serial MRI Scans During Radiation Therapy (RELAY)

MRI | Glioblastoma | Esophageal Cancer | Prostate Cancer | Vulvar Cancer | Magnetic Resonance Imaging | Radiotherapy | Pediatric Glioblastoma Multiforme

United States
National Cancer Institute (NCI)

Completed

MK2206 in Treating Patients With Advanced Refractory Biliary Cancer That Cannot Be Removed by Surgery

Advanced Adult Hepatocellular Carcinoma | Localized Non-Resectable Adult Liver Carcinoma | Recurrent Adult Liver Carcinoma | Recurrent Gallbladder Carcinoma | Stage IV Distal Bile Duct Cancer | Stage IV Gallbladder Cancer | Unresectable Extrahepatic Bile Duct Carcinoma | Unresectable Gallbladder...

United States
Angle plc
MidLantic Urology, LLC

Terminated

Characterization of Circulating Tumor Cells (CTCs) in High Risk and Early Metastatic Prostate Cancer Patients Using Parsortix® System (CHARTER)

Prostate Cancer | Castration-resistant Prostate Cancer | Biochemically Recurrent Prostate Carcinoma | High Risk Prostate Carcinoma

United States
Icahn School of Medicine at Mount Sinai
Patient-Centered Outcomes Research Institute

Completed

Improving Goals of Care Discussion in Advanced Cancer Patients

Melanoma | Glioblastoma | Colorectal Cancer | Cancer of Pancreas | Cancer of Stomach | Head or Neck Cancer | Stage III | Esophageal | Stage IV | Lung Cancers | Pancreatic Cancers | Primary Stage IV Hepatobiliary

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Alpelisib and Enzalutamide in Treating Patients With Androgen Receptor and PTEN Positive Metastatic Breast Cancer

Anatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditions

United States
YM BioSciences

Completed

Phase 2 Study of Nimotuzumab in Pediatric Recurrent Diffuse Intrinsic Pontine Glioma

Recurrent Diffuse Pontine Gliomas

United States, Canada, Israel
National Cancer Institute (NCI)

Completed

Bortezomib in Treating Patients With Advanced Cancer and Kidney Dysfunction

Stage III Multiple Myeloma | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse... and other conditions

United States
Ohio State University

Completed

Physiological Brain Atlas Development

Depression | Parkinson Disease | Obsessive Compulsive Disorder | Dystonia | Tremors

United States
Memorial Sloan Kettering Cancer Center
Columbia University; Genentech, Inc.; University of California, San Francisco

Completed

Hypofractionated Stereotactic Radiotherapy With Bevacizumab in the Treatment of Recurrent Malignant Glioma

Glioblastoma | Brain Cancer | Anaplastic Astrocytoma (AA) | Anaplastic Oligodendroglioma (AO) | MALIGNANT GLIOMA | Anaplastic Oligo-astrocytoma (AOA) | Anaplastic Mixed Gliomas | Malignant Glioma NOS

United States
Massachusetts General Hospital
Merck Sharp & Dohme LLC; Eisai Inc.

Not yet recruiting

Lenvatinib and Pembrolizumab Combination Therapy In HPV-associated Recurrent Respiratory Papilloma Patients With Laryngeal, Tracheal, and/or Pulmonary Involvement

Human Papilloma Virus | Recurrent Respiratory Papillomatosis

United States
Baylor College of Medicine
National Institute on Minority Health and Health Disparities (NIMHD)

Enrolling by invitation

Prospective Evaluation of Self-Testing to Increase Screening (PRESTIS)

Cervical Cancer | Human Papillomavirus Infection

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI); Oregon Health and Science University; Kaiser... and other collaborators

Completed

CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers

Breast Carcinoma | Cervical Carcinoma | Colorectal Carcinoma | Malignant Neoplasm | Human Papillomavirus Infection | Health Status Unknown

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Nivolumab and Ipilimumab in People With Aggressive Pituitary Tumors

Pituitary | Pituitary Tumor | Pituitary Cancer | Pituitary Carcinoma

United States
Julie Krystal
Janssen Pharmaceuticals

Recruiting

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Glioblastoma Multiforme | Gliosarcoma | Anaplastic Astrocytoma | Pleomorphic Xanthoastrocytoma | Pilocytic Astrocytoma | Diffuse Intrinsic Pontine Glioma | Low-grade Glioma | DIPG | Brainstem Glioma | Optic Nerve Glioma | Pilomyxoid Astrocytoma | Glioma, Astrocytic

United States
AstraZeneca
Merck Sharp & Dohme LLC; GOG Foundation; Myriad Genetic Laboratories, Inc.

Active, not recruiting

Olaparib Maintenance Monotherapy in Patients With BRCA Mutated Ovarian Cancer Following First Line Platinum Based Chemotherapy. (SOLO-1)

Advanced Ovarian Cancer | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete Response | BRCA Mutation | First Line Platinum Chemotherapy

Korea, Republic of, France, Italy, United States, Israel, Canada, China, Brazil, United Kingdom, Poland, Australia, Japan, Netherlands, Russian Federation, Spain
Nielsen BioSciences, Inc.

Recruiting

Candin for the Treatment of Common Warts

Common Warts (Verruca Vulgaris)

United States
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Study of the Disease Process of Lymphangioleiomyomatosis

Pneumothorax | Tuberous Sclerosis | Lung Disease | Lymphangioleiomyomatosis

United States
NYU Langone Health
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas

neurofibromatosis1 (NF1) | Recurrent or Progressive Optic Pathway Gliomas (OPG) | Recurrent or Progressive Low-grade Glioma

United States
M.D. Anderson Cancer Center

Recruiting

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Prehabilitation for Stage IIIC-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

Stage IIIC Fallopian Tube Cancer AJCC v8 | Stage IIIC Ovarian Cancer AJCC v8 | Stage IIIC Primary Peritoneal Cancer AJCC v8 | Stage IV Fallopian Tube Cancer AJCC v8 | Stage IV Ovarian Cancer AJCC v8 | Stage IV Primary Peritoneal Cancer AJCC v8 | Advanced Ovarian Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Docetaxel, Cisplatin and Fluorouracil in Treating Patients With Previously Untreated Stage II-IV Nasal Cavity and Paranasal Sinus Cancer

Sinonasal Undifferentiated Carcinoma | Locally Advanced Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma | Nasal Cavity and Paranasal Sinus Poorly Differentiated Carcinoma | Stage II Nasal Cavity and Paranasal Sinus Cancer AJCC v8 | Stage III Nasal Cavity and Paranasal Sinus Cancer... and other conditions

United States
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma... and other conditions

United States
National Cancer Institute (NCI)

Terminated

BMS-247550 in Treating Patients With Liver or Gallbladder Cancer

Advanced Adult Primary Liver Cancer | Localized Extrahepatic Bile Duct Cancer | Localized Gallbladder Cancer | Localized Resectable Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer | Recurrent Extrahepatic Bile Duct Cancer | Recurrent... and other conditions

United States
Georgetown University
Solstice Neurosciences

Completed

Myobloc Atrophy Study (MAS)

Stroke | Brain Injury | Tumor | Spinal Cord Injury (SCI) | Spasticity Secondary to Either a Disorder or Trauma

United States
National Cancer Institute (NCI)

Terminated

Oblimersen and Gemcitabine in Treating Patients With Advanced Solid Tumor or Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Terminated

SB-715992 in Treating Patients With Metastatic or Unresectable Solid Tumors or Hodgkin's or Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Recruiting

Bevacizumab in Adults With Recurrent Respiratory Papillomatosis (RRP)

Pathologic Processes | Infections | Neoplasms | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Neoplasms by Histologic Type | Neoplasms, Glandular and Epithelial | Recurrence | Disease Attributes | Papilloma | DNA Virus Infections | Papillomavirus Infections | Tumor Virus Infections | Neoplasms...

United States
Indiana University
National Cancer Institute (NCI); Indiana University Health; Eskenazi Health

Active, not recruiting

Facilitating Adaptive Coping With Fear of Recurrence Among Breast Cancer Survivors

Breast Cancer | Anxiety | Breast Neoplasm | Breast Carcinoma | Fear | Cancer of Breast | Malignant Tumor of Breast | Malignant Neoplasm of Breast | Mammary Cancer | Mammary Neoplasms, Human | Human Mammary Carcinoma | Mammary Carcinoma, Human

United States
Mayo Clinic

Completed

Copeptin as a Biomarker for Central Diabetes Insipidus Development Following Pituitary Surgery

Pituitary Tumor | Sellar and Suprasellar Masses

United States
Medical College of Wisconsin

Completed

Dexmedetomidine and Propofol for Pediatric MRI Sedation

Headache | Neurofibromatoses | Abdominal Neoplasm | Tumor | Seizure Disorder | Hydrocephalus | Spine Deformity

United States
St. Jude Children's Research Hospital

Completed

Treatment of Burkitt Lymphoma/Leukemia and B Large Cell NHL

Non-Hodgkin Lymphoma | Acute Lymphoblastic Leukemia, Mature B-Cell

United States
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Vinblastine and Methotrexate in Treating Children With Desmoid Tumors

Desmoid Tumor

United States, Australia, Canada

Clinical Trials on Advanced Solid Tumors in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kyrgyzstan

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations