Clinical Trials on Alternative Surgical Treatment for Aortic Valve Disease

Total 1973 results

Shanghai MicroPort Medical (Group) Co., Ltd.

Unknown

Safety and Efficacy Study of MicroPort's Transcatheter Aortic Valve and Delivery System for TAVI

Aortic Valve Stenosis | Aortic Valve Disease | Aortic Valve Calcification

China
Seung-Jung Park
CardioVascular Research Foundation, Korea

Completed

The Bicuspid Aortic Stenosis Following Transcatheter Aortic Valve Replacement Registry (Bicuspid TAVR)

Cardiovascular Diseases | Aortic Valve Stenosis | Heart Valve Diseases | Bicuspid

Korea, Republic of
Nantes University Hospital

Completed

Burden Comorbidities and Transcatheter Aortic Valve Implantation (TAVIQUAL)

Symptomatic Severe Aortic Valve Stenosis in Older Patients

France
Hospital Universitari Vall d'Hebron Research Institute

Not yet recruiting

Single Perclose Escalation Technique for Vascular Closure in TAVR

Aortic Valve Stenosis | Structural Valve Degeneration | Structural Valve Deterioration

Spain
Abbott Medical Devices

Completed

FlexNav EU CE Mark Study

Symptomatic Severe Aortic Stenosis

Denmark, Switzerland, United Kingdom, Italy
Abbott Medical Devices

Withdrawn

Assessment of St Jude Medical Portico Re-sheathable Transapical Aortic Valve System (Portico TA EU)

Severe Symptomatic Aortic Stenosis

United Kingdom
Sheba Medical Center

Unknown

Evaluation of Association Between Apical Dysfunction and Trans Apical Access for TAVR, in Patients With Severe Aortic Stenosis, Undergoing Trans Apical Trans Catheter Aortic Valve Replacement (TAP-TAVR).

Severe Symptomatic Aortic Stenosis

Israel
National Heart, Lung, and Blood Institute (NHLBI)

Withdrawn

Structural Heart and Valve Network PROSPECTIVE Registry

Heart Failure | Aortic Valve Stenosis | Mitral Valve Regurgitation | Heart Valve Disease | Tricuspid Valve Regurgitation

United States
LianBio LLC

Completed

Study Evaluating the Pharmacokinetics of Mavacamten in Healthy Adult Chinese Subjects

Hypertrophic Cardiomyopathy

China
HealthCore-NERI
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Valsartan for Attenuating Disease Evolution In Early Sarcomeric HCM (VANISH)

Hypertrophic Cardiomyopathy

United States, Canada
Sunnybrook Health Sciences Centre

Completed

Pilot Study of Cognitive and Functional Outcomes Following TAVI

Aortic Stenosis

Canada
Qilu Hospital of Shandong University

Recruiting

Effects of Levosimendan on Cardiac Function After TAVR in Patients With Heart Failure

Heart Failure | Aortic Stenosis, Severe

China
Abbott Medical Devices

Active, not recruiting

Portico NG Approval Study

Symptomatic Severe Aortic Stenosis

United States, Australia, Denmark, Italy, United Kingdom
Fundación EPIC

Recruiting

Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication

Aortic Valve Stenosis | Structural Valve Deterioration

Spain
Carilion Clinic

Terminated

Radial Versus Femoral Secondary Access During TAVI (R-TAVI)

Aortic Stenosis | Aortic Valve Disease | Vascular Access Complication

United States
National and Kapodistrian University of Athens
Centre Hospitalier Universitaire Saint Pierre

Recruiting

Rapid Atrial Pacing After TAVI to Predict Pacemaker Implantation

Aortic Valve Disease | Transcatheter Aortic Valve Implantation | TAVI

Belgium, Greece
RWTH Aachen University

Completed

Vitamin K Supplement for Inhibition of the Progress in Aortic Valve Calcification (08-002)

Aortic Valve Calcification

Germany
Venus MedTech (HangZhou) Inc.

Unknown

Safety and Performance of TAVI of Venus MedTech Aortic Valve Prosthesis (Venus-A)

Aortic Valve Stenosis | Aortic Valve Calcification

China
Modarres Hospital

Completed

Comparison of Aortic Root Dimension Changes During Cardiac Cycle Between the Patients With and Without Aortic Valve Calcification Using ECG-gated 64-slice and Dual-source 256-slice Computed Tomography Scanners: Results of a Multicenter Study

Aortic Valve Calcification

Iran, Islamic Republic of
Therenva
Centre Hospitalier Universitaire Dijon; University Hospital, Brest; Rennes University... and other collaborators

Unknown

Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut Workstation (COM-ENDO)

Aortic Aneurysm | Iliac Artery Stenosis | Iliac Aneurysm | Stenoses, Aortic

France
East and North Hertfordshire NHS Trust
Royal Brompton & Harefield NHS Foundation Trust

Not yet recruiting

Avr Thrombosis OutcoMe Study (ATOM)

Aortic Stenosis

United Kingdom
Erasmus Medical Center

Recruiting

Anxiety Reduction in TAVI Using Virtual Reality Trial (ART-VR)

Anxiety | Aortic Stenosis, Severe

Netherlands
Universitätsklinikum Hamburg-Eppendorf
Institut universitaire de cardiologie et de pneumologie de Québec, University...

Recruiting

Anatomic Stenosis Severity as a Prognostic Marker in Patients With Low-Flow Low-Gradient Aortic Stenosis Undergoing TAVI (ATLAS TAVI)

Low-Flow, Low-Gradient Aortic Stenosis

Israel, Denmark, Germany, Netherlands, France, United Kingdom, Canada
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute; University of Colorado, Denver; Emory University and other collaborators

Not yet recruiting

Promoting Shared Decision Making for Severe Aortic Stenosis (IMPACT SDM)

Aortic Stenosis

United States
University of Edinburgh

Recruiting

The Scottish Aortic Stenosis LongiTudinal Imaging and biomarkeR (SALTIRE) Programme (SALTIRE)

Aortic Stenosis

United Kingdom
Edwards Lifesciences

Active, not recruiting

PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic Stenosis (P3)

Aortic Stenosis

United States, Australia, Japan, Canada, New Zealand
Peijia Medical Technology (Suzhou) Co., Ltd.
General Hospital of Shenyang Military Region; West China Hospital; Second Affiliated... and other collaborators

Active, not recruiting

Safety and Efficacy of TaurusOne® Transcatheter Aortic Valve System in Patients With Severe Calcific Aortic Stenosis

Aortic Stenosis

China
Edwards Lifesciences

Active, not recruiting

A Clinical Trial of Transcatheter Aortic Valves in Dialysis Patients (Japan)

Aortic Stenosis

Japan
Edwards Lifesciences

Active, not recruiting

SAPIEN 3 Ultra EU PMS

Aortic Stenosis | Aortic Valve Stenosis

Portugal, Spain, Switzerland, Italy, United Kingdom, Finland, France, Germany, Austria, Norway
Avicena LLC

Withdrawn

Vivio AS (Aortic Stenosis) Algorithm Optimization Study

Aortic Stenosis

United States
Mayo Clinic

Completed

Prehabilitation to Improve Functional and Clinical Outcomes in Patients With Aortic Stenosis (TAVR-FRAILTY)

Aortic Stenosis

United States
Segeberger Kliniken GmbH

Completed

A Comparison of Transcatheter Heart Valves in High Risk Patients With Severe Aortic Stenosis: The CHOICE Trial (CHOICE)

Aortic Stenosis

Germany
Institute of Cardiology, Warsaw, Poland

Unknown

"Cardiac Rehabilitation in Patients With Hypertrophic Cardiomyopathy".

Cardiac Rehabilitation

Poland
Asan Medical Center
Merck Sharp & Dohme LLC

Terminated

Effect of Bisoprolol on Progression of Aortic Stenosis (BLAST)

Aortic Stenosis

Korea, Republic of
University Hospital, Toulouse

Completed

The Plasma Serotonin and Aortic Stenosis: a Pilot Study. (SERAOPI)

Aortic Stenosis

France
Seoul St. Mary's Hospital

Unknown

18F-NaF Uptake and Aortic Stenosis Progression

Aortic Stenosis
Duke University

Terminated

Utility of Exercise-induced N-terminal (NT) Pro-brain Natriuretic Peptide Levels in Predicting Prognosis in Asymptomatic Aortic Stenosis (AS-BNP)

Aortic Stenosis

United States
Rigshospitalet, Denmark

Unknown

Acute Haemodynamic Effects of Treatment With Angiotensin Converting Enzyme (ACE)-Inhibitors in Patients With Symptomatic Aortic Stenosis

Aortic Stenosis

Denmark
The Cleveland Clinic

Terminated

Speckle Tracking Imaging in Patients With Low Ejection Fraction Aortic Stenosis (SPArKLE-AS) (SPArKLE-AS)

Aortic Stenosis

United States
Marvin Eng
William Beaumont Hospitals

Enrolling by invitation

Supra-Annular vs. Annular ValvEs for Small Annuli (SAVE)

Aortic Valve Stenosis | Implantation, Heart Valve Prosthesis

United States
Hospital Universitari Son Dureta
Laboratorios BIOMED SA

Unknown

Value of Oral Phytate (InsP6) in the Prevention of Progression of the Cardiovascular Calcifications (CALCIFICA)

Aortic Stenosis | Heart Valve Disease

Spain
University Hospital, Montpellier

Completed

Post TAVI Coronary REVASCularisation Guided by Myocardial Perfusion Imaging: a Prospective Open Label Pilot Study: The REVASC-TAVI Study (REVASC-TAVI)

Stable Coronary Disease | Severe and Symptomatic Aortic Stenosis

France
Assiut University

Completed

Phase Contrast in Valvular Heart Disease

Valvular Heart Disease (Aortic and Mitral Valves)

Egypt
RWTH Aachen University

Completed

Examination of Valve Insufficiency Before and After MitraClip or TAVI Procedure by 3D Echocardiography Compared to MRI (3D_TTE_TAVI)

Aortic Stenosis | Mitral Valve Insufficiency | Development of Standardized Assessment TAVI and MitraClip Procedures by Echocardiography

Germany
Catharina Ziekenhuis Eindhoven

Completed

Pre- and Post TAVI Cognitive Functioning and Intraoperative Carotid Flow Measurements

Cognitive Impairment | Aortic Stenosis, Severe | Older People--Abuse of

Netherlands
Sahajanand Medical Technologies Limited
Qmed Consulting A/S

Recruiting

Hydra Single-centre Experience - Copenhagen, Denmark

Aortic Valve Stenosis

Denmark
Fundación EPIC

Recruiting

Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI Implantation (FAST TRACK)

Aortic Valve Stenosis | Aortic Valve Disease | Heart Valve Diseases

Spain
Ole De Backer

Recruiting

Re-hospitalisation After Transcatheter Aortic Valve Implantation (HOSPITAVI)

Aortic Valve Stenosis | Aortic Valve Disease

Denmark
Guilherme Attizzani, MD

Recruiting

MRI in Transcatheter Aortic Valve Replacement Patients (MRI in TAVR)

Aortic Valve Stenosis

United States
Leipzig Heart Science gGmbH
Heart Center Leipzig - University Hospital

Recruiting

RanDOmized stUdy Comparing Both Latest Generation Self-Expanding Valves and a Minimalist approaCH vs. Standard Of Care In transCathEter Aortic Valve Implantation (DOUBLE-CHOICE)

Aortic Valve Stenosis

Germany

Clinical Trials on Alternative Surgical Treatment for Aortic Valve Disease

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