Clinical Trials on Amiloidosis Beta2M

Total 962 results

University of Pennsylvania

Recruiting

Molecular Imaging of the Underlying Mechanism of Cardiotoxicity in Patients With Light Chain Amyloidosis Using PET/CT

Cardiac Amyloidosis

United States
French Cardiology Society
Pfizer; Henri Mondor University Hospital

Active, not recruiting

Prevalence and Post-surgical Outcomes of CARdiac Wild-type TransthyrEtin amyloidoSIs in Elderly Patients With Aortic steNosis Referred for Valvular Replacement. (AMYLOCARTESIAN)

Aortic Valve Stenosis | Amyloidosis | Aging | Heart Disease

France
Universitair Ziekenhuis Brussel

Recruiting

Prevalence of Wild-type TTR Cardiac Amyloidosis in Patients With Polyneuropathy of Unknown Cause.

Amyloidosis | Polyneuropathy

Belgium
University Hospital Inselspital, Berne

Active, not recruiting

ATTR Amyloidosis in Elderly Patients With Aortic Stenosis

Aortic Stenosis Symptomatic | Amyloidosis Cardiac

Switzerland
First Affiliated Hospital Xi'an Jiaotong University

Enrolling by invitation

The Diagnostic Pattern and Prognosis of Multiple Myeloma Patients With Myocardial Amyloidosis Were Evaluated by NMR Based Metabolomics

Multiple Myeloma | Amyloidosis Cardiac

China
Steen Hvitfeldt Poulsen

Completed

The Effect of Trimetazidine on Mitochondrial Function, Myocardial Performance, and Invasive Hemodynamics in Patients Diagnosed With Wild-Type Transthyretin Cardiac Amyloidosis (CACTuS - TMZ)

Transthyretin Amyloid Cardiopathy | Mitochondrial Pathology

Denmark
Fundación Pública Andaluza para la gestión de la...

Recruiting

Registry of Patients With Suspected Amyloidosis in Heart Failure (Regamic)

Heart Failure

Spain
Fundación Pública Andaluza para la gestión de la...

Unknown

Prevalence of Amyloidosis in Heart Failure (PREVAMIC) (PREVAMIC)

Heart Failure

Spain
University Hospital of Ferrara

Recruiting

Analysis of Calcium Score of Severe Aortic Stenosis in Patients With and Without Cardiac Amyloidosis (CAUSATIVE Study) (CAUSATIVE)

Aortic Stenosis, Severe | Amyloidosis Cardiac

Italy
University Hospital, Bordeaux
University of Bordeaux

Completed

Early and Systematic Screening in Chronic Neuropathy (TTR-FAP)

Amyloid Neuropathies, Familial

France
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation

Multiple Myeloma and Plasma Cell Neoplasm | Drug/Agent Toxicity by Tissue/Organ

United States
Insel Gruppe AG, University Hospital Bern
Luzerner Kantonsspital; Cantonal Hospital of St. Gallen; Triemli Hospital

Recruiting

Swiss Cardiac Amyloidosis REgistry (Swiss-CARE) (B-CARE)

Amyloid Cardiomyopathy

Switzerland
Philippe Meyer

Recruiting

Effect of Radiotherapy on ATTR Cardiac Amyloidosis : a Proof of Concept Study

Amyloid Cardiomyopathy

Switzerland
Massachusetts General Hospital

Completed

Characteristics of Patients With Amyloidosis & Heart Failure Being Evaluated for a Heart Transplant

Cardiomyopathy
Intellia Therapeutics

Recruiting

Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001

Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy | Wild-Type Transthyretin Cardiac Amyloidosis

United Kingdom, New Zealand, Sweden
Intellia Therapeutics

Active, not recruiting

Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM)

Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy | Wild-Type Transthyretin Cardiac Amyloidosis

France, United Kingdom, New Zealand, Sweden
Washington University School of Medicine
Karyopharm Therapeutics Inc

Recruiting

Selinexor and Lenalidomide for Consolidation and Maintenance Treatment in Multiple Myeloma Post-transplant

Multiple Myeloma | Myeloma-Associated Amyloidosis

United States
National Institute of Allergy and Infectious Diseases...

Active, not recruiting

Natural History of Severe Allergic Inflammation and Reactions

PGM3 Deficiency | Eosinophilic and/or Atopic Dermatitis | OSMR Deficiency | Primary Localized Cutaneous Amyloidosis | Hereditary Alpha-tryptasemia

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Ixazomib With Cyclophosphamide and Dexamethasone in Patients With Previously Untreated Symptomatic Multiple Myeloma or Light Chain Amyloidosis

Amyloidosis | Plasma Cell Myeloma

United States
Pfizer

Completed

Safety and Efficacy Study of Fx-1006A in Patients With Familial Amyloidosis

Familial Amyloid Polyneuropathy

United Kingdom, Spain, United States, Argentina, Brazil, France, Germany, Portugal, Sweden
National Center for Research Resources (NCRR)
Indiana University School of Medicine

Unknown

Study of Systemic Amyloidosis Presentation and Prognosis

Amyloidosis

United States
Jordan Collaborating Cardiology Group

Not yet recruiting

Prevalence of ATTR Cardiac Amyloidosis in Patients Undergoing TAVR

Aortic Valve Stenosis | Severe Aortic Stenosis | ATTR Amyloidosis Wild Type | Middle East Studies
Centre Hospitalier Régional d'Orléans

Recruiting

Amyloidosis TTR Flow Reserve Evaluation (AMYTRE)

Amyloid Cardiomyopathy

France
Mathew S. Maurer
National Heart, Lung, and Blood Institute (NHLBI); Yale University; Boston Medical... and other collaborators

Recruiting

Screening for Cardiac Amyloidosis With Nuclear Imaging for Minority Populations (SCAN-MP)

Amyloid Cardiomyopathy, Transthyretin-Related

United States
Pfizer

Active, not recruiting

A Study to Learn About the Study Medicine Called Tafamidis 61mg in People Diagnosed With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin Amyloid Cardiomyopathy

Korea, Republic of
Pfizer

Completed

A Study to Assess the Safety and Efficacy Of Tafamidis In Chinese Participants With Transthyretin Amyloid Cardiomyopathy (ATTR-CM)

Transthyretin Amyloid Cardiomyopathy

China
Ionis Pharmaceuticals, Inc.

Completed

Extension Study Assessing Long Term Safety and Efficacy of IONIS-TTR Rx in Familial Amyloid Polyneuropathy (FAP)

Amyloidosis | Familial Amyloid Polyneuropathy | FAP | TTR | Transthyretin

United States, Spain, Argentina, Brazil, France, Germany, Italy, Portugal, United Kingdom
Aarhus University Hospital Skejby
Regional Hospital Holstebro

Completed

Prevalence of Wild Type Transthyretin Cardiac Amyloidosis in Patients Operated for Idiopathic Carpal Tunnel Syndrome (CACTuS)

Carpal Tunnel Syndrome | Amyloidosis Cardiac

Denmark
Ionis Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Amyloidosis | Familial Amyloid Polyneuropathy | FAP | TTR | Transthyretin

New Zealand, United States, Spain, Argentina, Brazil, France, Germany, Italy, Portugal, United Kingdom
Peking University People's Hospital

Recruiting

Daratumumab, Bortezomib, Cyclophosphamide, and Dexamethasone Therapy for Patients With MIDD

Monoclonal Gammopathy of Renal Significance

China
University of Leipzig

Active, not recruiting

Native T1 CMR Imaging for Diagnosis of Cardiac Amyloidosis (CMR for CA)

Heart Failure NYHA Class II | Heart Failure NYHA Class III | Heart Failure With Preserved Ejection Fraction | Hypertrophy, Left Ventricular | Heart Failure NYHA Class IV | Cardiac Amyloidosis | Heart Failure With Mid Range Ejection Fraction

Germany
Eidos Therapeutics, a BridgeBio company

Withdrawn

Efficacy and Safety of Acoramidis (AG10) in Subjects With Transthyretin Amyloid Polyneurophathy (ATTRibute-PN)

Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy
Barbara Ann Karmanos Cancer Institute

Completed

COVID-19 VAX Booster Dosing in Patients With Hematologic Malignancies

Multiple Myeloma | AL Amyloidosis | Chronic Lymphocytic Leukemia

United States
Alnylam Pharmaceuticals

Completed

The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis in Participants Who Have Already Been Treated With ALN-TTR02 (Patisiran)

Amyloidosis

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Netherlands, Portugal, Spain, Sweden, Taiwan, United Kingdom, Germany, France, Korea, Republic of, Brazil, Mexico, Turkey
Brigham and Women's Hospital

Unknown

24 Month Open Label Study of the Tolerability and Efficacy of Inotersen in TTR Amyloid Cardiomyopathy Patients

Amyloidosis

United States
Oregon Health and Science University
Ionis Pharmaceuticals, Inc.

Recruiting

carDIo-ttranSSfOrm nucLEar Imaging Study (DISSOLvE)

Amyloidosis | Transthyretin Amyloid Cardiomyopathy

United States
University of Trieste
Pfizer

Unknown

Unmasking the Prevalence of AC in an Unselected Echocardiographic Population (AC-TIVE)

Amyloid Cardiomyopathy

Italy
University Hospital, Toulouse

Terminated

Transthyretin Cardiac Amyloidosis in Patients With Idiopathic Carpal Tunnel Syndrome Referred for Release Surgery (PRATHYC)

Carpal Tunnel Syndrome | Transthyretin Amyloidosis

France
Pfizer

Completed

An Extension of Study Fx-005 Evaluating Long-Term Safety And Clinical Outcomes Of Fx-1006A In Patients With Transthyretin Amyloid Polyneuropathy

Familial Amyloid Polyneuropathy | ATTR-PN

Sweden, Brazil, Germany, Argentina, France, Portugal
University Hospital, Bordeaux

Completed

Neuropathy in Patients Monitored for Wild-type TTR Cardiac Amyloidosis (Non-mutated) (N-SAC)

Wild-type Amyloid Cardiopathy

France
AstraZeneca

Recruiting

EPIC-ATTR: A Study to Evaluate the Effect of Eplontersen on the Transthyretin Reduction and Long-term Safety in Chinese Subjects With Transthyretin Amyloid Cardiomyopathy (EPIC-ATTR)

Transthyretin Amyloid Cardiomyopathy

China
Pfizer

Recruiting

A Study to Learn About Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy (ATTR-CM) in India

Transthyretin Amyloid Cardiomyopathy

India
Brigham and Women's Hospital

Not yet recruiting

ION-682884 in Patients With TTR Amyloid Cardiomyopathy

Transthyretin Amyloid Cardiopathy

United States
Columbia University

Completed

SGLT2 Inhibitors in Transthyretin Amyloid Cardiomyopathy

Transthyretin Amyloid Cardiomyopathy

United States
Alnylam Pharmaceuticals

Completed

DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis

Familial Amyloidotic Cardiomyopathy (FAC)

United States, France, Spain, United Kingdom, Belgium, Brazil
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Daratumumab After Stem Cell Transplant in Treating Patients With Multiple Myeloma

Plasma Cell Myeloma | Secondary Amyloidosis

United States
Pfizer

Completed

The Effect Of Tafamidis For The Transthyretin Amyloid Polyneuropathy Patients With V30M Or Non-V30M Transthyretin

Transthyretin Familial Amyloid Polyneuropathy

Japan
Alexion Pharmaceuticals, Inc.

Recruiting

Study of ALXN2220 Versus Placebo in Adults With ATTR-CM (DepleTTR-CM)

Transthyretin Amyloid Cardiomyopathy

United States, Spain, United Kingdom, Norway, Israel, China, Korea, Republic of, Belgium, France, Germany, Italy, Japan, Australia, Argentina, Austria, Taiwan, Switzerland, Canada, Sweden, Poland, Denmark, Turkey, Brazil, Netherlands, G... and more
Neurimmune AG

Completed

First-in-Human Study of NI006 in Patients With Amyloid Transthyretin Cardiomyopathy

Amyloid Transthyretin Cardiomyopathy

Germany, France, Netherlands, Spain
Boston University

Completed

Safety and Effect of Doxycycline in Patients With Amyloidosis

Amyloidosis

United States

Clinical Trials on Amiloidosis Beta2M

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